Course
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Credits
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Scientific Disciplinary Sector Code
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Contact Hours
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Exercise Hours
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Laboratory Hours
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Personal Study Hours
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Type of Activity
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Language
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20410536 -
CELL BIOLOGY AND GENETIC ELEMENTS
(objectives)
The course aims to provide basic knowledge on the morpho-functional organization of animal cells and tissues, with particular attention to mammals. In addition, the students will be provided with the theoretical and practical skills for understanding the fundamental mechanisms of both Mendelian and non-Mendelian inheritance of characters and of environmental mutagenesis. The course also aims to provide students with basic knowledge relating to the development and anatomy of vertebrates from an evolutionary point of view. The basic information for understanding the differentiation and morphogenesis processes will be provided. The students will acquire basic knowledge on animal cells and tissues, on formal genetics and environmental mutagenesis for understanding chromosomal aberrations and, finally, on the general principles of animal development, from gametogenesis to organ formation. The students will also acquire the theoretical and practical skills necessary for the recognition at the macro- and microscopic level of anatomical and embryonic structures of vertebrates.
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CIANFANELLI VALENTINA
( syllabus)
The course is divided into 3 modules: (1) Cellular biology – Prof. Marco Colasanti Stem cells, differentiation and cell death; plasma membrane and membrane transport; DNA, nucleus, cell cycle, mitosis and meiosis; cellular organelles, proteins, cytoplasmic pathway, secretory pathway, vesicular trafficking; mitochondria and energy; cytoskeleton; cellular junctions; elements of histology. (2) Elements of Genetics – Prof. Antonella Sgura/Dr. Francesco Berardinelli Basic elements of genetics: organization of chromatin, hetero and euchromatin, the gene, the allele. The chromosome: structure and function. Homologous chromosomes, sister chromatids. Cell division: mitosis and meiosis. Defects of cell division and its consequences. Mendel and the concept of gene. Mendel's laws, numerical exercises. The chromosomal basis of inheritance, X-linked characters, numerical exercises(3) Developmental Biology/Comparative Anatomy – Dr. Valentina Cianfanelli General principles of developmental biology and comparative anatomy. Classification, General characters and phylogenetic relationships among the main taxa of vertebrates. From a single cell to a multicellular organism: differentiation and morphogenesis. Sexual reproduction. Gametes. Fecundation: recognition of gametes at a distance and by contact. General information on the various stages of development: segmentation, gastrulation, organogenesis. Protostomes and deuterostomes. Comparing the stages of development in echinoderms, amphibians, birds, and mammals. Germ layers. Neurulation. Organogenesis. Comparative anatomy of the organic systems of vertebrates. Eco-Devo: environment and developmental biology.
( reference books)
1) Cytology and Histology: (1) Miscellaneous authors. Biologia - Cellula e Tessuti, Colombo&Olmo eds, edi-ermes; (2) Molecole, Cellule e Organismi - Coordination by: E. Ginelli, M. Malcovati. EdiSES
2) Elements of Genetics: Campbell. Biologia e genetica, Urry, Cain, Wasserman, Minorsky and Orr. Pearson
3) Developmental Biology: Menegola et al. "Manuale di Biologia dello Sviluppo Animale", EdiSES
4) Comparative anatomy: Giavini, Menegola, “Manuale di Anatomia Comparata”, EdiSES
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SGURA ANTONELLA
( syllabus)
plasma membrane and membrane transport; DNA, nucleus, cell cycle, mitosis and meiosis; cellular organelles, proteins, cytoplasmic pathway, secretory pathway, vesicular trafficking; mitochondria and energy; cytoskeleton; cellular junctions; epithelial tissue; nerve tissue; muscle tissue; connective tissue; bone tissue; Blood; immunity. (2) Elements of Genetics. Basic elements of genetics: organization of chromatin, hetero and euchromatin, the gene, the allele. The chromosome: structure and function. Homologous chromosomes, sister chromatids. Cell division: mitosis and meiosis. Defects of cell division and its consequences. Mendel and the concept of gene. Mendel's laws, numerical exercises. Extension of Mendelian genetics (incomplete dominance, codominance, multiple alleles, pleiotropy, epistasis). The chromosomal basis of inheritance, X-linked characters, crossing over and linkage maps, two-point cross, three-point cross, numerical exercises. Basic concepts of population genetics, numerical exercises. The molecular basis of heredity, semi-conservative DNA replication. Numerical and structural chromosomal aberrations. (3) Developmental Biology and Comparative Anatomy. (Developmental Biology). From a single cell to a multicellular organism: differentiation and morphogenesis. Sexual reproduction. Gametogenesis. Structural differences between the egg and the sperm. Fertilization: recognition of gametes at a distance and by contact. General information on the various stages of development: segmentation, gastrulation, organogenesis. Protostomes and deuterostomes. Early stages of development of echinoderms, cephalochordates, amphibians, birds, and mammals. Neurulation and the formation of encephalic vesicles. The mesoderm and the fate of the regions into which it is divided. The extraembryonic annexes: amnios, chorion, allantoid and yolk sac. The placenta. (Comparative Anatomy). Origin of vertebrates. The first agnates and the appearance of gnathostomes. Diversity and evolutionary success of aquatic vertebrates read based on their anatomy and reproductive biology. Origin of tetrapods and conquest of the emerged lands. Chondroichthyes, osteichthyes, amphibians, reptiles, birds and mammals. Comparative anatomy of the organic systems of vertebrates: integumentary, respiratory, digestive and circulatory and uro-genital systems.
( reference books)
1) Cytology and Histology: Miscellaneous authors. Biologia - Cellula e Tessuti, Colombo&Olmo eds, edi-ermes. 2) Elements of Genetics: Campbell. Biologia e genetica, Urry, Cain, Wasserman, Minorsky and Orr. Pearson 3) Developmental Biology: Menegola et al. "Manuale di Biologia dello Sviluppo Animale", EdiSES 4) Comparative anatomy: Stingo "Anatomia Comparata", Edi-Ermes
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BERARDINELLI FRANCESCO
( syllabus)
Inglese The course is divided into 3 modules: (1) Cellular biology– Prof. Marco Colasanti Stem cells, differentiation and cell death; plasma membrane and membrane transport; DNA, nucleus, cell cycle, mitosis and meiosis; cellular organelles, proteins, cytoplasmic pathway, secretory pathway, vesicular trafficking; mitochondria and energy; cytoskeleton; cellular junctions; elements of histology. (2) Elements of Genetics – Prof. Antonella Sgura/Dr. Francesco Berardinelli Basic elements of genetics: organization of chromatin, hetero and euchromatin, the gene, the allele. The chromosome: structure and function. Homologous chromosomes, sister chromatids. Cell division: mitosis and meiosis. Defects of cell division and its consequences. Mendel and the concept of gene. Mendel's laws, numerical exercises.The chromosomal basis of inheritance, X-linked characters, numerical exercises. (3) Developmental Biology/Comparative Anatomy – Dr. Valentina Cianfanelli General principles of developmental biology and comparative anatomy. Classification, General characters and phylogenetic relationships among the main taxa of vertebrates. From a single cell to a multicellular organism: differentiation and morphogenesis. Sexual reproduction. Gametes. Fecundation: recognition of gametes at a distance and by contact. General information on the various stages of development: segmentation, gastrulation, organogenesis. Protostomes and deuterostomes. Comparing the stages of development in echinoderms, amphibians, birds, and mammals. Germ layers. Neurulation. Organogenesis. Comparative anatomy of the organic systems of vertebrates. Eco-Devo: environment and developmental biology.
( reference books)
1) Cytology and Histology: (1) Miscellaneous authors. Biologia - Cellula e Tessuti, Colombo&Olmo eds, edi-ermes; (2) Molecole, Cellule e Organismi - Coordination by: E. Ginelli, M. Malcovati. EdiSES 2) Elements of Genetics: Campbell. Biologia e genetica, Urry, Cain, Wasserman, Minorsky and Orr. Pearson 3) Developmental Biology: Menegola et al. "Manuale di Biologia dello Sviluppo Animale", EdiSES 4) Comparative anatomy: Giavini, Menegola, “Manuale di Anatomia Comparata”, EdiSES
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6
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BIO/06
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40
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10
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-
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-
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Core compulsory activities
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3
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BIO/18
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16
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10
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-
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-
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Core compulsory activities
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ITA |
20410540 -
INTEGRATED COURSE OF BIOCHEMISTRY, MOLECULAR BIOLOGY AND MICROBIOLOGY
(objectives)
The module of General and Environmental Microbiology aims to provide the basic principles of the structure, function and evolution of microbial cells, with particular regard to bacteria. The knowledge and skills acquired in this module will represent a reference framework for understanding the role of microorganisms in natural and anthropic environments and for the study of the biotechnological applications of microorganisms for environmental protection and sustainability. The module aims at the acquisition of Cultural Competences, i.e. basic knowledge, on (i) the structural, functional and metabolic diversity present in the microbial world, (ii) the mechanisms responsible for the structure and the functioning of bacterial cells, (iii) the processes driving the evolution of bacterial species, (iv) the structure, diversity and life cycles of viruses, (v) the methods and approaches for the study of microbial communities, (vi) the role and effects of microorganisms in the environment. The module also aims at the acquisition of Methodological Competences, i.e. the understanding, through both theoretical lessons and practical activities, of the scientific bases and methodological approaches for the study of bacteria in natural environments and in the laboratory, and for the characterization of complex microbial populations by culture and molecular techniques. A further aim is also the acquisition of the ability to interpret microbiological data and analyse the scientific literature to obtain information on the structure and function of microorganisms, with the final goal to understand natural or artificial events involving microorganisms. The second module of the course: Elements of Biochemistry aims to provide the basic notions related to the structure and function of biological macromolecules, enzymatic catalysis and cell metabolism. These notions are necessary for the continuation of studies on the functioning of eukaryotic and prokaryotic organisms in the context of the Degree Course. The Educational Objectives are the acquisition of cultural skills, i.e. basic knowledge about the structure and function of biological macromolecules (nucleic acids, proteins, carbohydrates, lipids) and the mechanisms that regulate the synthesis and degradation of biological macromolecules. Furthermore, the module aims to provide basic knowledge on the mechanisms by which genetic information is conserved, transmitted and expressed properties. The Educational Objectives are also the acquisition of Methodological Competences, or the acquisition, through practical laboratory activity, of the scientific and methodological bases of the most important experimental techniques in the field of Biochemistry and Molecular Biology and the acquisition, through the elaboration and display of individual papers, of the ability to find in the scientific literature information on the structure and function of biological macromolecules capable of contextualizing, analyzing and critically interpreting natural or artificial events involving biological macromolecules.
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ELEMENTS OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
(objectives)
The second module of the course: Elements of Biochemistry aims to provide the basic notions related to the structure and function of biological macromolecules, enzymatic catalysis and cell metabolism. These notions are necessary for the continuation of studies on the functioning of eukaryotic and prokaryotic organisms in the context of the Degree Course. The Educational Objectives are the acquisition of cultural skills, i.e. basic knowledge about the structure and function of biological macromolecules (nucleic acids, proteins, carbohydrates, lipids) and the mechanisms that regulate the synthesis and degradation of biological macromolecules. Furthermore, the module aims to provide basic knowledge on the mechanisms by which genetic information is conserved, transmitted and expressed properties. The Educational Objectives are also the acquisition of Methodological Competences, or the acquisition, through practical laboratory activity, of the scientific and methodological bases of the most important experimental techniques in the field of Biochemistry and Molecular Biology and the acquisition, through the elaboration and display of individual papers, of the ability to find in the scientific literature information on the structure and function of biological macromolecules capable of contextualizing, analyzing and critically interpreting natural or artificial events involving biological macromolecules.
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GALLO VALENTINA
( syllabus)
The course aims to provide students with basic knowledge of cell biochemistry and metabolism. Carbohydrates, lipids, amino acids, and proteins: protein structure and examples of structure-function relationships. Enzymes and enzymatic catalysis: definition of the active site and substrate specificity; the Michaelis-Menten equation, enzyme inhibition. Introduction to aerobic and anaerobic metabolism. Metabolism of carbohydrates, lipids, and nitrogenous compounds. Energy production in mitochondria.
The course also aims to provide basic knowledge of molecular biology. Specifically, the syllabus includes the study of purine and pyrimidine nucleotides; the structure and function of nucleic acids; the structure of prokaryotic and eukaryotic chromosomes; replication, transcription, translation; recombinant DNA technology, and genetically modified organisms.
( reference books)
Massimo Stefani, Niccolò Taddei. Chimica, Biochimica e Biologia Applicata Zanichelli Editore
Francesco Amaldi, Piero Benedetti, Graziano Pesole, Paolo Plevani BIOLOGIA MOLECOLARE Casa Editrice Ambrosiana
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3
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BIO/10
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24
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-
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-
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-
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Core compulsory activities
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3
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BIO/11
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24
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-
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-
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-
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Core compulsory activities
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ITA |
20410883 -
FUNDAMENTALS OF PALAEONTOLOGY
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ANGELONE CHIARA
( syllabus)
Introduction to the history of Palaeontology (2h). Taphonomy (2h). Systematics: classification. The species concept. different taxonomy schools (2h). Palaeoecology: marine palaeoecology. Elements of continental palaeoecology. Palaeoichnology (4h). Biostratigraphy: biozones. Biostratigraphic correlations (4h). Evolution: fossils and evolution. Lamark’s and Neo-lamarckist’s evoluton theory. Darwin’s evolution theory. Microevolution. Synthetic and Punctuated Equilibria theories. Macroevolution. Extinction. Adaptive radiation (8h). Palaeobiogeography: the historical biogeography: dispersion and vicariance. The ecological biogeography. Plate tectonics and palaeobiogeography (2h).
The origin of life (2h) The Cambrian "explosion" (2h) Selection of fossil organisms (20h)
( reference books)
AAVV, 2020 - Manuale di Paleontologia. Fondamenti e applicazioni. Idelson-Gnocchi; Raffi S. & Serpagli E., 1993 - Introduzione Alla Paleontologia. U.T.E.T.; Benton M.J. & Harper D.A.T., 2009 - Introduction to Paleobiology and the fossil record, Wiley-Blackwell.
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6
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GEO/01
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48
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-
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-
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Core compulsory activities
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ITA |
20410537 -
INTEGRATED COURSE OF MINERALOGY AND PETROGRAPHY
(objectives)
The first didactic unit (mineralogy and georesources) aims to provide the student with a basic knowledge of geological mineralogy, an introduction to the exploitation of mineral resources with the connected environmental sustainability issues, and the use of geological materials in science, art and technology. The second didactic unit (petrography) aims to provide knowledge of the behavior and properties of metamorphic and sedimentary igneous rocks in the evolution of planet Earth. The expected learning outcomes are the students’ ability to recognize and contextualize rocks and minerals in the territory, to have perception of their meaning in terms of genesis and geological evolution, and to understand their human use in the context of respect for the environment.
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PETROGRAPHY
(objectives)
The second didactic unit (petrography) aims to provide knowledge of the behavior and properties of metamorphic and sedimentary igneous rocks in the evolution of planet Earth. The expected learning outcomes are the students’ ability to recognize and contextualize rocks and minerals in the territory, to have perception of their meaning in terms of genesis and geological evolution, and to understand their human use in the context of respect for the environment.
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VONA ALESSANDRO
( syllabus)
PART I – THE GEOLOGICAL CONTEXT Lesson I – Composition and Structure of the Earth Lesson II – Plate Tectonics and the Rock Cycle
PART II – IGNEOUS ROCKS Lesson III – The Nature of Magma Lesson IV – Occurrence and Classification of Igneous Rocks Lesson V – Magma Generation, Ascent, and Differentiation Lesson VI – Rock Melting and Magma Crystallization Lesson VII – Volcanism
PART III – SEDIMENTARY ROCKS Lesson VIII – Sediment Formation, Transport, and Lithification Lesson IX – Classification of Sedimentary Rocks
PART IV – METAMORPHIC ROCKS Lesson X – The Metamorphic Process and Metamorphic Rocks
PART V – ROCK IDENTIFICATION IN THIN SECTION (LABORATORY OF OPTICAL PETROGRAPHY)
( reference books)
MINERALOGIA E PETROGRAFIA – C. Klein, A.R. Philpotts (Zanichelli) MATERIALE DIDATTICO (Testi, Grafici ed Esercizi) DISTRIBUITO DAL DOCENTE
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3
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GEO/07
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20
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-
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5
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-
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Basic compulsory activities
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3
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GEO/07
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20
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-
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5
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-
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Core compulsory activities
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ITA |
Optional group:
Insegnamenti a scelta II o III anno - (show)
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12
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20410603 -
Environmental mutagenesis
(objectives)
To provide knowledge on mutagenesis and repair of genetic damage starting from the concepts of classical and molecular cytogenetics. To provide theoretical and practical skills for the execution of genotoxicity tests and for the criteria for the identification of bioindicator organisms suitable for environmental biomonitoring, aimed at assessing the genotoxic risk in different environmental matrices.
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BERARDINELLI FRANCESCO
( syllabus)
Gene and chromosomal mutations, DNA repair systems, effects of genome alterations in somatic and germline cells. Physical mutagens, chemical mutagens, and their metabolism. Genotoxic pollutants in air, water, and soil matrices. In vitro tests in prokaryotic and eukaryotic cells, in vivo tests on model organisms. Application of mutagenesis tests to environmental biomonitoring and human population biomonitoring. Basics of environmental legislation.
( reference books)
Genomica e Mutagenesi Ambientale - Various Authors - Edited by Lucia Migliore - Zanichelli
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6
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BIO/18
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48
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-
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-
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-
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Elective activities
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ITA |
20410396 -
DIDACTIC OF MATHEMATICS
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6
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MAT/04
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56
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-
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-
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-
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Elective activities
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ITA |
20402348 -
INTRODUCTION TO SEDIMENTOLOGY
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6
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GEO/02
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48
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-
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-
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-
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Elective activities
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ITA |
20402347 -
INTRODUCTION TO TECTONICS
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Derived from
20402347 INTRODUZIONE ALLA TETTONICA in Scienze geologiche L-34 N0 FUNICIELLO FRANCESCA
( syllabus)
INTRODUCTION. GENERAL FOUNDATIONS. CRUST (OCEANIC AND CONTINENTAL), LITHOSPHERE (OCEANIC AND CONTINENTAL) AND MANTLE: OVERVIEW ON COMPOSITION, STRUCTURE, RHEOLOGY, THERMAL PROFILE. TECTONICS: HISTORICAL BACKGROUND. PLATE MARGINS. EXTENSIONAL TECTONICS: GEOMETRY AND KINEMATICS OF NORMAL FAULTS, ORIGIN OF RIFT SYSTEMS, RIFTING MODELS, AND EVOLUTION OF A RIFTING SYSTEM, SEDIMENTATION/TOPOGRAPHY AND MAGMATISM ASSOCIATED TO RIFTING, MID-OCEAN RIDGES, PASSIVE MARGINS. COMPRESSIVE TECTONICS: GEOMETRY, KINEMATICS AND DYNAMICS OF CONVERGENT AND COLLISIONAL MARGINS, OBLIQUE CONVERGENCE, ARCHITECTURE, KINEMATICS AND MECHANICS OF COLLISIONAL BELTS. STRIKE-SLIP TECTONICS: TRANSFORM AND STRIKE-SLIP FAULTS AND RELATED GEODYNAMICS, TRANSPRESSION AND TRANSTENSION, PULL-APART BASINS. HOT SPOT AND MANTLE PLUMES. HAZARD LINKED TO TECTONIC PROCESSES: DEFINITION OF RISK, EARTHQUAKES, MEGA-EARTHQUAKES, TSUNAMI, VOLCANOES, LAND-SLIDES. INTEGRATION: GEOMAPAPP, SEISMIC METHODS, ANALOG MODELING, NUMERICAL MODELING AS TOOLS TO STUDY TECTONIC PROCESSES.
( reference books)
- EARTH STRUCTURE: AN INTRODUCTION TO STRUCTURAL GEOLOGY AND TECTONICS (SECOND EDITION). B. A. VAN DER PLUIJM , S. MARSHAK (NORTON & COMPANY, 2004) - PLATE BOUNDARY ZONES. S. STEIN, J.T. FREYMUELLER, ED. AGU GEODYNAMIC SERIES, VOL. 30, 2002. - DYNAMIC EARTH, PLATES, PLUMES AND MANTLE CONVECTION, DAVIES, G.F., CAMBRIDGE UNIVERSITY PRESS, 1999. - GEODYNAMICS: SECOND EDITION, TURCOTTE, D. L. AND SCHUBERT, G., JOHN WILEY & SONS, NEW YORK, 2002. - GEOLOGIA STRUTTURALE. H. FOSSEN, ZANICHELLI 2020. - BIBLIO PROVIDED DURING THE COURSE
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6
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GEO/03
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40
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-
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12
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Elective activities
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ITA |
20402176 -
VERTEBRATE PALEONTOLOGY
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Derived from
20402176 PALEONTOLOGIA DEI VERTEBRATI in Geologia e Tutela dell'Ambiente LM-74 ANGELONE CHIARA
( syllabus)
Introduction, chordates, basal vertebrates: 3h "Agnatha" and the origin of lower jaw: 3h Chondrychtyes and e osteichthyes: 3h Sarcopterygians and the origin of tetrapods: 3h Amphibia: 3h Anapsida: 3h Diapsida: 3h Dinosauria: 3h Pterosauria vs. Aves: 3h Sinapsida: 3h Mesozoic mammals-Metatheria: 3h Afrotheria and Xenartra: 3h Boreoeutheria: 3h Laurasiatheria: 3h Euarchontoglires: 3h Primates: 3h
( reference books)
The reference textbook is: Benton M.J. (2014) - Vertebrate Palaeontology. Blackwell Publishing
Additional references to be discussed during the classes will be selected among the most recent and/or controversial.
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6
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GEO/01
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48
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-
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-
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-
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Elective activities
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ITA |
20402395 -
GEORESOURCES AND GEOMATERIALS
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6
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GEO/06
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48
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-
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-
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-
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Elective activities
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ITA |
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