Degree Course: Ecosystems Biodiversity and Management Syllabus for A.Y. 2015/2016

Italian version

FIRST YEAR

First semester

Course	Credits	Scientific Disciplinary Sector Code	Contact Hours	Exercise Hours	Laboratory Hours	Personal Study Hours	Type of Activity	Language
20401643 - STATISTICAL ANALYSIS FOR ECOLOGY AND SYSTEMATICS (objectives) HYPOTHESIS FORMULATION AND TESTING. DESCRIPTIVE AND THEORETICAL STATISTICS. DEMOGRAPHIC DYNAMICS. MATHEMATICAL MODELS IN ECOLOGY. PRACTICE USE OF SOME STATISTICAL SOFTWARES. - LUISELLI LUCA MARIA	6	SECS-S/02	48	-	-	-	Core compulsory activities	ITA
20402500 - PLANT BIODIVERSITY (objectives) APPRECIATE THE BEAUTY OF PLANTS IN A DEFINITE FRAME OF TAXOMOMIC HIERARCHY; KNOWLEDGE OF THE MORPHOLOGICAL CHARACTERS USEFUL TO SYSTEMATICS AND PHYLOGENESIS; RECOGNIZE WITH EMPHASIS THE MAIN AND MOST IMPORTANT PLANTS IN ITALY; USE OF TECHNIQUES AND SKILLS FOR THE FLORA STUDIES: HERBARIUM, ANALYTICAL KEYS, SURVEY IN FIELD, ETC.
20402500-1 - MODULO 1 - LUCCHESE FERNANDO (syllabus) METHODS AND PRINCIPLES OF PLANT SYSTEMATICS (1 CREDIT). DEFINITION OF PLANT SYSTEMATICS AS THE BIODIVERSITY STUDY AND EVOLUTIONARY HISTORY OF THE PLANTS. CLASSIFICATION. USE OF CHARACTERS: MORPHOLOGY, CHEMISTRY, EMBRIOLOGY, CHROMOSOMES, GENETICS; GOOD AND BAD CHARACTERS. MOLECULAR SYSTEMATICS. SPECIATION PROCESSES: SPECIES CONCEPT AND DEFINITION, GENE FLOW, INTROGRESSION, HYBRIDIZATION, GEOGRAPHIC AND GENETIC ISOLATION, APOMIXY, POLYPLOIDY. BIOGEOGRAPHY AND ECOLOGY OF PLANTS. SKILLS FOR THE SYSTEMATICS STUDY: BOTANICAL GARDENS, HERBARIA, LIBRARY, ANALYTICAL KEYS, NOMENCLATURE CODEX. GAMETOPHYTE AND SPOROPHYTE HISTORY AND EVOLUTION. MOLECULAR PHYLOGENESIS TECHNIQUES AND APG SYSTEMATICS: OLD AND NEW IN PLANT SYSTEMATICS. SYSTEMATICS AND DISTRIBUTION OF PTERIDOPHYTA (1 CREDIT), EVOLUTION FROM PSYLOPHITES TO FERNS. SYSTEMATICS AND DISTRIBUTION OF GYMNOSPERMAE (1 CREDIT), EVOLUTION FROM GYNKOACEAE TO GNETACEAE. SYSTEMATICS AND DISTRIBUTION OF ANGIOSPERMAE (2 CREDITS). TECNIQUES FOR THE LABORATORY STUDY OF MORPHOLOGICAL CHARACTERS (MICROSCOPY AND DISSECTION), FLORAL FORMULAS, AND IN FIELD (LENS). COLLECT MATERIAL FROM FIELD AND IDENTIFICATION. EXCURSION IN FIELD AND SPECIES IDENTIFICATION. (reference books) CD LECTURES STRASSBURGER, BOTANICA SISTEMATICA VOL 2°, DELFINO. PIGNATTI S., 1982. FLORA D’ITALIA, 1-2-3 VOL, ED. EDAGRICOLE	5	BIO/02	40	-	-	-	Core compulsory activities	ITA
20402500-2 - MODULO 2 - LUCCHESE FERNANDO (syllabus) METHODS AND PRINCIPLES OF PLANT SYSTEMATICS (1 CREDIT). DEFINITION OF PLANT SYSTEMATICS AS THE BIODIVERSITY STUDY AND EVOLUTIONARY HISTORY OF THE PLANTS. CLASSIFICATION. USE OF CHARACTERS: MORPHOLOGY, CHEMISTRY, EMBRIOLOGY, CHROMOSOMES, GENETICS; GOOD AND BAD CHARACTERS. MOLECULAR SYSTEMATICS. SPECIATION PROCESSES: SPECIES CONCEPT AND DEFINITION, GENE FLOW, INTROGRESSION, HYBRIDIZATION, GEOGRAPHIC AND GENETIC ISOLATION, APOMIXY, POLYPLOIDY. BIOGEOGRAPHY AND ECOLOGY OF PLANTS. SKILLS FOR THE SYSTEMATICS STUDY: BOTANICAL GARDENS, HERBARIA, LIBRARY, ANALYTICAL KEYS, NOMENCLATURE CODEX. GAMETOPHYTE AND SPOROPHYTE HISTORY AND EVOLUTION. MOLECULAR PHYLOGENESIS TECHNIQUES AND APG SYSTEMATICS: OLD AND NEW IN PLANT SYSTEMATICS. SYSTEMATICS AND DISTRIBUTION OF PTERIDOPHYTA (1 CREDIT), EVOLUTION FROM PSYLOPHITES TO FERNS. SYSTEMATICS AND DISTRIBUTION OF GYMNOSPERMAE (1 CREDIT), EVOLUTION FROM GYNKOACEAE TO GNETACEAE. SYSTEMATICS AND DISTRIBUTION OF ANGIOSPERMAE (2 CREDITS). TECNIQUES FOR THE LABORATORY STUDY OF MORPHOLOGICAL CHARACTERS (MICROSCOPY AND DISSECTION), FLORAL FORMULAS, AND IN FIELD (LENS). COLLECT MATERIAL FROM FIELD AND IDENTIFICATION. EXCURSION IN FIELD AND SPECIES IDENTIFICATION. (reference books) CD LECTURES STRASSBURGER, BOTANICA SISTEMATICA VOL 2°, DELFINO. PIGNATTI S., 1982. FLORA D’ITALIA, 1-2-3 VOL, ED. EDAGRICOLE	1	BIO/02	-	10	-	-	Core compulsory activities	ITA
20402501 - VERTEBRATE DIVERSITY (objectives) AFTER THE COURSE, THE STUDENTS SHOULD BE ABLE TO: 1) DESCRIBE IN PHYLOGENETIC TERMS THE MORPHOLOGICAL, BIOGEOGRAPHICAL AND ECOLOGICAL TRAITS OF THE FOCAL GROUPS OF VERTEBRATES SELECTED FOR THE COURSE (CF. THE ELECTRONIC FILES GIVEN BY THE PROFESSOR); 2) ASSIGN A GIVEN SPECIES OF VERTEBRATE TO ITS HIGHER TAXONOMIC GROUPS AND DISCUSS ITS PHYLOGENETIC POSITION; 3) BE ABLE TO RECOGNIZE AT SPECIES LEVEL THE VERTEBRATES OF THE EUROPEAN FAUNA, WITH SPECIAL REGARD TO THE SPECIES OF CONSERVATION CONCERN OR ECONOMIC INTEREST (FISHERY, ACQUACULTURE, HUNTING, PET TRADE, PEST MANAGEMENT, ECC.); 4) WORKING FOR PUBLIC AND PRIVATE AGENCIES ON NATIONAL AND INTERNATIONAL PROJECTS FOCUSED ON BIODIVERSITY CONSERVATION, WILDLIFE MANAGEMENT AND SUSTAINABLE EXPLOITATION OF ANIMAL RESOURCES.
20402501-1 - MODULO 1 - CARPANETO GIUSEPPE (syllabus) THE COURSE IS AN INTRODUCTION TO THE STUDY OF DIVERSITY AND EVOLUTION OF VERTEBRATES (FISHES, AMPHIBIANS, REPTILES, BIRDS AND MAMMALS) IN SPACE AND TIME, THROUGH A PHYLOGENETIC AND BIOGEOGRAPHIC PERSPECTIVE. A NUMBER OF SELECTED TAXONOMIC GROUPS OF EACH CLASS OF VERTEBRATES ARE DISCUSSED IN TERMS OF EVOLUTIONARY HISTORY, PHYLOGENETIC RECONSTRUCTION, ECOLOGICAL AND GEOGRAPHICAL DISTRIBUTION, ETHOLOGICAL ASPECTS, SHORT AND LONG TERM TURNOVER, RARITY AND EXTINCTION IN RELATION TO INTERSPECIFIC COMPETITION, CLIMATIC CHANGES AND HUMAN IMPACT ON ECOSYSTEMS. THE SELECTED TAXONOMIC GROUPS ARE TREATED IN THE ELECTRONIC FILES GIVEN BY THE PROFESSOR. WITHIN THEM THE STUDENT WILL IDENTIFY THE MOST REPRESENTATIVE SPECIES OF THE EUROPEAN FAUNA WHICH MAY BE A TOPIC TO BE DISCUSSED DURING THE EXAM, WITH THE RECOGNITION OF SPECIES BELONGING TO THE ITALIAN FAUNA OR TO THE FAUNA OF HIS OWN COUNTRY (ERASMUS STUDENTS). NUMBER OF CREDITS: 5 CREDITS OF LECTURES (40 HOURS) + 1 CREDIT OF FIELD SURVEY (AROUND 10 HOURS IN THREE SELECTED MEDITERRANEAN HABITATS), WITH A SPECIAL ATTENTION TO TERRESTRIAL VERTEBRATES. (reference books) - HICKMAN CP ET AL. 2008/2012. DIVERSITÀ ANIMALE. MCGRAW-HILL, MILANO (FOURTH OR FIFTEENTH EDIZIONS). (STUDY THE LAST FIVE CHAPTERS, DEALING WITH VERTEBRATES). - FIELD GUIDES TO THE IDENTIFICATION OF MAMMALS, BIRDS, REPTILES, AMPHIBIANS AND FISHES OF EUROPE (ASK THE PROFESSOR THE NEW EDITIONS AVAILABLE IN EACH LANGUAGE). - ELECTRONIC FILES GIVEN BY THE PROFESSOR. The professor receives every day from 15:00 to 18:30 by appointment via email: giuseppe.carpaneto@uniroma3.it	5	BIO/05	40	-	-	-	Core compulsory activities	ITA
20402501-2 - MODULO 2 - CARPANETO GIUSEPPE (syllabus) THE COURSE IS AN INTRODUCTION TO THE STUDY OF DIVERSITY AND EVOLUTION OF VERTEBRATES (FISHES, AMPHIBIANS, REPTILES, BIRDS AND MAMMALS) IN SPACE AND TIME, THROUGH A PHYLOGENETIC AND BIOGEOGRAPHIC PERSPECTIVE. A NUMBER OF SELECTED TAXONOMIC GROUPS OF EACH CLASS OF VERTEBRATES ARE DISCUSSED IN TERMS OF EVOLUTIONARY HISTORY, PHYLOGENETIC RECONSTRUCTION, ECOLOGICAL AND GEOGRAPHICAL DISTRIBUTION, ETHOLOGICAL ASPECTS, SHORT AND LONG TERM TURNOVER, RARITY AND EXTINCTION IN RELATION TO INTERSPECIFIC COMPETITION, CLIMATIC CHANGES AND HUMAN IMPACT ON ECOSYSTEMS. THE SELECTED TAXONOMIC GROUPS ARE TREATED IN THE ELECTRONIC FILES GIVEN BY THE PROFESSOR. WITHIN THEM THE STUDENT WILL IDENTIFY THE MOST REPRESENTATIVE SPECIES OF THE EUROPEAN FAUNA WHICH MAY BE A TOPIC TO BE DISCUSSED DURING THE EXAM, WITH THE RECOGNITION OF SPECIES BELONGING TO THE ITALIAN FAUNA OR TO THE FAUNA OF HIS OWN COUNTRY (ERASMUS STUDENTS). NUMBER OF CREDITS: 5 CREDITS OF LECTURES (40 HOURS) + 1 CREDIT OF FIELD SURVEY (AROUND 10 HOURS IN THREE SELECTED MEDITERRANEAN HABITATS), WITH A SPECIAL ATTENTION TO TERRESTRIAL VERTEBRATES. (reference books) - HICKMAN CP ET AL. 2008/2012. DIVERSITÀ ANIMALE. MCGRAW-HILL, MILANO (FOURTH OR FIFTEENTH EDIZIONS). (STUDY THE LAST FIVE CHAPTERS, DEALING WITH VERTEBRATES). - FIELD GUIDES TO THE IDENTIFICATION OF MAMMALS, BIRDS, REPTILES, AMPHIBIANS AND FISHES OF EUROPE (ASK THE PROFESSOR THE NEW EDITIONS AVAILABLE IN EACH LANGUAGE). - ELECTRONIC FILES GIVEN BY THE PROFESSOR. The professor receives every day from 15:00 to 18:30 by appointment via email: giuseppe.carpaneto@uniroma3.it	1	BIO/05	-	10	-	-	Core compulsory activities	ITA
20402502 - CONSERVATION BIOLOGY (objectives) THE MAIN FORMATIVE TARGETS ARE: 1) TO ACQUIRE AN ECOLOGICAL AND BIOGEGRAPHIC APPROACH TO THE CONSERVATION BIOLOGY OF PLANT AND ANIMAL POPULATIONS AND SPECIES, AND OF ECOSYSTEMS.(2) TO ACQUIRE BASIC KNOWLEDGE ON THE POPULATION ECOLOGY AND GENETICS APPLIED TO THE CONSERVATION OF BIODIVERSITY, AND ANALYSE PROBLEMS CONCERNING HUMAN AND NATURE INTERACTIONS. (3) TO ACQUIRE A FIELD AND LAB EXPERIMENTAL EXPERIENCE ON CONSERVATION BIOLOGY; 4) TO LEAD THE STUDENTS TOWARDS A SELF-EVALUATION OF THEIR OWN COMPETENCE WHITIN CONSERVATION BIOLOGY. - BOLOGNA MARCO ALBERTO (syllabus) THE COURSE CONSISTS OF A MODULE OF LESSONS AND SOME FIELD AND LAB PRACTICES CONCERNING POPULATION AND COMMUNITYECOLOGY AND GENETICS. LESSONS ARE DEVOTED TO STUDY THE FOLLOWING SUBJECTS OF GENERAL, PLANT AND ANIMAL CONSERVATION BIOLOGY: (A) ORGANISATION OF THE COURSE. PRINCIPLES AND PROBLEMS OF CONSERVATION BIOLOGY AT INTERNATIONAL AND NATIONAL LEVELS. DESTRUCTION, TRANSFORMATIONA NAD CONSERVATION OF TERRESTRIAL, FRESHWATER AND MARINE HABITATS. (B) LEVELS OF BIODIVERSITY, FROM MOLECULES TO ECOSYSTEMS, AND THEIR CONSERVATION. (C) BIOGEOGRAPHIC, ECOLOGICAL AND HUMAN CAUSES OF POPULATION AND ECOSYSTEM FRAGMENTATION. EFFETCTS OF FRAGMENTATION: REDUCTION OF INDIVIDUALS, POPULATIONS AND GENE FLOW; EXTINCTION. (D)ECOLOGY OF POPULATIONS AND COMMUNITIES APPLIED TO THE CONSERVATION OF PLANT AND ANIMAL SPECIES: MONITORING, MAINTENANCE, RESTORATION (RESTOCKING, REPLANTING, REINTRODUCTION); IN SITU AND EX SITU PROJECTS). (E) CONSERVATION GENETICS OF PLANT AND ANIMAL SPECIES: MOLECULAR SYSTEMATICS APPLIED TO CONSERVATION; ESTIMATE OF GENETIC DIVERSITY AND INBRREEDING LEVEL IN ENDANGERED POPULATIONS. (F) AUTOCTHONOUS AND ALLOCTONOUS POPULATIONS AND SPECIES; BIOGEOGRAPHIC, ECOLOGICAL AND GENETIC POLLUTION, ERADICATION AND PATROL. (G) ECOLOGICAL NETWORKS, PROTECTED AND NOT PROTECTED AREAS. (H) CONSERVATION CATEGORIES, EUROPEAN AND ITALIAN RULES ON PROTECTED AREAS, RED LISTS. ETHICS OF CONSERVATION AND EDUCATION. (reference books) PRIMACK R.B. & BOITANI L. 2012.BIOLOGIA DELLA CONSERVAZIONE. ZANICHELLI (WITH WEBSITE) The power point files may be downloaded from the website: https://www.scienze.uniroma3.it/courses/4/details/2018/didactic_activities/1575 The professor receives every day from 15:00 to 18:30 by appointment via email: marcoalberto.bologna@uniroma3.it - CUTINI MAURIZIO (syllabus) THE COURSE CONSISTS OF A MODULE OF LESSONS AND SOME FIELD AND LAB PRACTICES CONCERNING POPULATION AND COMMUNITYECOLOGY AND GENETICS. LESSONS ARE DEVOTED TO STUDY THE FOLLOWING SUBJECTS OF GENERAL, PLANT AND ANIMAL CONSERVATION BIOLOGY: (A) ORGANISATION OF THE COURSE. PRINCIPLES AND PROBLEMS OF CONSERVATION BIOLOGY AT INTERNATIONAL AND NATIONAL LEVELS. DESTRUCTION, TRANSFORMATIONA NAD CONSERVATION OF TERRESTRIAL, FRESHWATER AND MARINE HABITATS. (B) LEVELS OF BIODIVERSITY, FROM MOLECULES TO ECOSYSTEMS, AND THEIR CONSERVATION. (C) BIOGEOGRAPHIC, ECOLOGICAL AND HUMAN CAUSES OF POPULATION AND ECOSYSTEM FRAGMENTATION. EFFETCTS OF FRAGMENTATION: REDUCTION OF INDIVIDUALS, POPULATIONS AND GENE FLOW; EXTINCTION. (D)ECOLOGY OF POPULATIONS AND COMMUNITIES APPLIED TO THE CONSERVATION OF PLANT AND ANIMAL SPECIES: MONITORING, MAINTENANCE, RESTORATION (RESTOCKING, REPLANTING, REINTRODUCTION); IN SITU AND EX SITU PROJECTS). (E) CONSERVATION GENETICS OF PLANT AND ANIMAL SPECIES: MOLECULAR SYSTEMATICS APPLIED TO CONSERVATION; ESTIMATE OF GENETIC DIVERSITY AND INBRREEDING LEVEL IN ENDANGERED POPULATIONS. (F) AUTOCTHONOUS AND ALLOCTONOUS POPULATIONS AND SPECIES; BIOGEOGRAPHIC, ECOLOGICAL AND GENETIC POLLUTION, ERADICATION AND PATROL. (G) ECOLOGICAL NETWORKS, PROTECTED AND NOT PROTECTED AREAS. (H) CONSERVATION CATEGORIES, EUROPEAN AND ITALIAN RULES ON PROTECTED AREAS, RED LISTS. ETHICS OF CONSERVATION AND EDUCATION. (reference books) P RIMACK R.B. & BOITANI L. 2012.BIOLOGIA DELLA CONSERVAZIONE. ZANICHELLI (WITH WEBSITE) - MANCINI EMILIANO (syllabus) THE COURSE CONSISTS OF A MODULE OF LESSONS AND SOME FIELD AND LAB PRACTICES CONCERNING POPULATION AND COMMUNITYECOLOGY AND GENETICS. LESSONS ARE DEVOTED TO STUDY THE FOLLOWING SUBJECTS OF GENERAL, PLANT AND ANIMAL CONSERVATION BIOLOGY: (A) ORGANISATION OF THE COURSE. PRINCIPLES AND PROBLEMS OF CONSERVATION BIOLOGY AT INTERNATIONAL AND NATIONAL LEVELS. DESTRUCTION, TRANSFORMATIONA NAD CONSERVATION OF TERRESTRIAL, FRESHWATER AND MARINE HABITATS. (B) LEVELS OF BIODIVERSITY, FROM MOLECULES TO ECOSYSTEMS, AND THEIR CONSERVATION. (C) BIOGEOGRAPHIC, ECOLOGICAL AND HUMAN CAUSES OF POPULATION AND ECOSYSTEM FRAGMENTATION. EFFETCTS OF FRAGMENTATION: REDUCTION OF INDIVIDUALS, POPULATIONS AND GENE FLOW; EXTINCTION. (D)ECOLOGY OF POPULATIONS AND COMMUNITIES APPLIED TO THE CONSERVATION OF PLANT AND ANIMAL SPECIES: MONITORING, MAINTENANCE, RESTORATION (RESTOCKING, REPLANTING, REINTRODUCTION); IN SITU AND EX SITU PROJECTS). (E) CONSERVATION GENETICS OF PLANT AND ANIMAL SPECIES: MOLECULAR SYSTEMATICS APPLIED TO CONSERVATION; ESTIMATE OF GENETIC DIVERSITY AND INBRREEDING LEVEL IN ENDANGERED POPULATIONS. (F) AUTOCTHONOUS AND ALLOCTONOUS POPULATIONS AND SPECIES; BIOGEOGRAPHIC, ECOLOGICAL AND GENETIC POLLUTION, ERADICATION AND PATROL. (G) ECOLOGICAL NETWORKS, PROTECTED AND NOT PROTECTED AREAS. (H) CONSERVATION CATEGORIES, EUROPEAN AND ITALIAN RULES ON PROTECTED AREAS, RED LISTS. ETHICS OF CONSERVATION AND EDUCATION. (reference books) P RIMACK R.B. & BOITANI L. 2012.BIOLOGIA DELLA CONSERVAZIONE. ZANICHELLI (WITH WEBSITE)	6	BIO/07	48	-	-	-	Core compulsory activities	ITA

Second semester

Course	Credits	Scientific Disciplinary Sector Code	Contact Hours	Exercise Hours	Laboratory Hours	Personal Study Hours	Type of Activity	Language
20401641 - PLANT ECOLOGY (objectives) MAJOR GOALS OF THIS COURSE ARE: TO INTENSIFY A KNOWLEDGE OF THE MAIN FEATURES OF PLANT COMMUNITIES; TO GET THE MASTERY OF THE MAIN METODOLOGIES OF VEGETATION STUDY; TO ACQUIRE THE ABILITY TO INTERPRET ECOSYSTEMS PHENOMENA AND CORRELATE THEM WITH VEGETATION DYNAMICS; TO DEVELOP THE INTERPRETATION OF ECOLOGICAL DATA AND READ THE SPECIFIC PAPER IN PLANT ECOLOGY, GEOBOTANY AND PHYTOGEOGRAPHY.
20401641-2 - MODULO 2 - CANEVA GIULIA (syllabus) DEFINITION OF THE DIFFERENT GOALS OF THE PLANT ECOLOGY AND RELATIONSHIP WITH OTHER ENVIRONMENTAL SUBJECT; DEFINITION OF PLANT COMMUNITIES. CLIMATE-SOIL-VEGETATION EQUILIBRIUM; ZONAL, EXTRAZONAL, AZONAL VEGETATION. THE CONCEPT OF POTENTIAL NATURAL VEGETATION. CLIMATE AND BIOCLIMATE; CLIMATIC INDICES AND DIAGRAMS. ZONE AND VEGETATION BELT. LABORATORY: CLIMATIC INDICES AND DIAGRAMS; BIOLOGICAL AND CHOROLOGICAL SPECTRA VEGETATION MAPS MAIN FEATURES OF THE VEGETATION; STRUCTURE AND PHYSIOGNOMY, BIOLOGICAL FORM AND LIFE FORM, DISTRIBUTION AND CHOROLOGICAL TYPES, VEGETATION DYNAMICS. DIFFERENT METHODS OF VEGETATION STUDY; SYNCRONIC AND DIACRONIC APPROACHS. VEGETATION MAPPING. HUMAN IMPACT AND EFFECT ON VEGETATION. CLIMATIC INDICES AND DIAGRAMS; BIOLOGICAL AND CHOROLOGICAL SPECTRA VEGETATION MAPS (reference books) BRECKLE S.-W., 2002. WALTER’S VEGETATION OF THE EARTH. SPRINGER. GIACOMINI V., FENAROLI L., 1958. LA FLORA. TCI. PIGNATTI S., (ED.), 1995. ECOLOGIA VEGETALE. UTET. PIGNATTI S., 1976. GEOBOTANICA. UTET. VAN DER MAAREL E. (ED.), 2005. VEGETATION ECOLOGY. BLACKWELL PUBLISH. - CUTINI MAURIZIO	2	BIO/03	-	20	-	-	Core compulsory activities	ITA
20401641-1 - MODULO 1 - CANEVA GIULIA (syllabus) DEFINITION OF THE DIFFERENT GOALS OF THE PLANT ECOLOGY AND RELATIONSHIP WITH OTHER ENVIRONMENTAL SUBJECT; DEFINITION OF PLANT COMMUNITIES. CLIMATE-SOIL-VEGETATION EQUILIBRIUM; ZONAL, EXTRAZONAL, AZONAL VEGETATION. THE CONCEPT OF POTENTIAL NATURAL VEGETATION. CLIMATE AND BIOCLIMATE; CLIMATIC INDICES AND DIAGRAMS. ZONE AND VEGETATION BELT. LABORATORY: CLIMATIC INDICES AND DIAGRAMS; BIOLOGICAL AND CHOROLOGICAL SPECTRA VEGETATION MAPS MAIN FEATURES OF THE VEGETATION; STRUCTURE AND PHYSIOGNOMY, BIOLOGICAL FORM AND LIFE FORM, DISTRIBUTION AND CHOROLOGICAL TYPES, VEGETATION DYNAMICS. DIFFERENT METHODS OF VEGETATION STUDY; SYNCRONIC AND DIACRONIC APPROACHS. VEGETATION MAPPING. HUMAN IMPACT AND EFFECT ON VEGETATION. CLIMATIC INDICES AND DIAGRAMS; BIOLOGICAL AND CHOROLOGICAL SPECTRA VEGETATION MAPS (reference books) BRECKLE S.-W., 2002. WALTER’S VEGETATION OF THE EARTH. SPRINGER. GIACOMINI V., FENAROLI L., 1958. LA FLORA. TCI. PIGNATTI S., (ED.), 1995. ECOLOGIA VEGETALE. UTET. PIGNATTI S., 1976. GEOBOTANICA. UTET. VAN DER MAAREL E. (ED.), 2005. VEGETATION ECOLOGY. BLACKWELL PUBLISH.	4	BIO/03	32	-	-	-	Core compulsory activities	ITA
20401642 - ANIMAL ECOLOGY (objectives) THE MAIN FORMATIVE TARGETS ARE: 1) TO ACQUIRE AN EVOLUTIONARY APPROACH IN THE STUDY OF ANIMAL ECOLOGY; 2) TO ACQUIRE BASIC KNOWLEDGE ON AUTOECOLOGY, SYNECOLOGY AND POPULATION ECOLOGY; 3) TO ACQUIRE AN EXPERIMENTAL FIELD EXPERIENCE IN THE COLLECTION AND ANALYSIS OF FIELD DATA ON POPULATION AND COMMUNITY ECOLOGY; 4) TO LEAD THE STUDENTS TOWARDS A SELF-EVALUATION OF THEIR OWN COMPETENCE WHITIN ANIMAL ECOLOGY.
20401642-2 - MODULO 2 - VIGNOLI LEONARDO (syllabus) Cultural skills (Knowledge of:) The course offers the conceptual bases for (A) understanding the bases of population ecology (B) understanding the community ecology (C) understanding the behavioural ecology (D) understanding the macroecology (E) an evolutionary approach to the study of animal ecology. Methodological skills (Knowing how to perform:) acquire the critical thinking through readings and discussions, in order to correctly evaluate a research hypothesis, choose research tools and interpret results. SYLLABUS THE COURSE CONSISTS OF A PRELIMINARY MODULE OF LESSONS AND ONE OR TWO FINAL RESIDENTIAL STAGES IN A NATURAL ENVIRONMENT, INCLUDING BOTH THEORETICAL LESSONS AND SEVERAL FIELD PRACTICES CONCERNING ASPECTS OF POPULATION AND COMMUNITY ECOLOGY, HABITAT PREFERENCE AND RESOURCE PARTITIONING BY THE SPECIES. THE PRELIMINARY MODULE IS DEVOTED TO STUDY THE FOLLOWING SUBJECTS: (a) STRUCTURAL LEVELS OF ANIMAL DIVERSITY. (a) ANIMAL ADAPTATIONS TO THE ECOLOGICAL CHARACTERISTICS OF BIOMES. (b) ANIMAL COMMUNITY ECOLOGY: INTRA- AND INTER-SPECIFIC RELATIONSHIPS; EXAMPLES OF ANIMAL COMMUNITIES OF AQUATIC AND TERRESTRIAL HABITATS; QUALITATIVE AND QUANTITATIVES METHODS FOR ANALYSING ANIMAL COMMUNITY; DIVERSITY, EVENESS AND DOMINANCE, INDICES; (c) ANIMAL POPULATION ECOLOGY: STRUCTURE, DYNAMICS, REGULATION, AGE CLASSES, SEX-RATIO; ESTIMATION OF POPULATIONS SIZE AND DENSITY, CAPTURE AND RECAPTURE METHODS; (d) AUTOECOLOGY: RESEARCH METHODS AND DATA ANALYSES; DEFINITION OF ECOLOGICAL NICHE AND STUDY CASES: REPRODUCTIVE, TROPHIC, SPATIAL (HOME RANGE, TERRITORY), TEMPORAL (PHENOLOGY, LYFE CYCLES), NICHES. THE COURSE PROVIDES, IN ADDITION TO THE RESIDENTIAL STAGE (CA. 6 HOURS A DAY OF PRACTICES IN NATURE AND 2 HOURS A DAY OF LECTURES), ALSO 2-3 EXERCISES IN NATURE OF A SINGLE DAY, INTERVALED TO THE FRONTAL LESSONS IN THE FIRST MODULE. (reference books) NOTES AND POWER POINTS ARE PROVIDED BY THE TEACHER. THE FOLLOWING TEXTBOOKS HELP TO STUDY SOME ASPECTS OF THE PROGRAMME: - RICKLEFS R.E., 1997. ECOLOGIA. ZANICHELLI; - BOITANI L. & FULLER T.K. (EDS.), 2000. RESEARCH TECHNIQUES IN ANIMAL ECOLOGY. CONTROVERSIES AND CONSEQUENCES. COLUMBIA UNIVERSITY PRESS, N.Y.; - KREBS J.R. & DAVIES N.B., 2002. ECOLOGIA E COMPORTAMENTO ANIMALE. BOLLATI BORINGHIERI; - GOTELLI, N.J. AND A.M. ELLISON. 2004. A PRIMER OF ECOLOGICAL STATISTICS. SINAUER ASSOCIATES, INC., SUNDERLAND, MA.; - GOTELLI, N.J. 2008. A PRIMER OF ECOLOGY. 4TH EDITION. SINAUER ASSOCIATES, INC., SUNDERLAND, MA. - HENDERSON, P.A. 2003. PRACTICAL METHODS IN ECOLOGY. BLACKWELL SCIENCE LTD Students are provided with a document that lists for each lesson topic which textbook and which chapters are most relevant for the study, and for each topic it lists recent scientific papers for further study. Students are also provided with PDFs of lessons and of scientific papers suggested. - BOLOGNA MARCO ALBERTO (syllabus) SIGNAL PERCEPTION AND TRANSDUCTION PATHWAYS IN PLANT CELLS: RECEPTORS, MEDIATORS AND MODALITY OF TRANSDUCTION. SIGNALING PATHWAYS UPON HORMONE OR LIGHT PERCEPTION. CELL WALL AT THE INTERFACE BETWEEN INTRACELLULAR AND EXTRACELLULAR ENVIRONMENT: CELL SURFACE SENSORS AND RECEPTORS. ROLE OF REACTIVE OXYGEN SPECIES IN SIGNAL TRANSDUCTION. PHENOTYPIC PLASTICITY IN RESPONSES TO ABIOTIC STRESSES (DROUGHT, FLOODING, SALT STRESS, HIGH AND LOW TEMPERATURE, HIGH LIGHT). SECONDARY METABOLISM AND DEFENCE STRATEGY AGAINST WOUNDING OR PATHOGEN ATTACK. INNATE IMMUNITY AND EFFECTOR TRIGGERED IMMUNITY. LOCAL AND SYSTEMIC DEFENCE RESPONSES. PLANT COMPOUNDS AS SOURCE OF DRUGS, NUTRACEUTICAL FOOD OR NATURAL HERBICIDES. BASIC KNOWLEDGE IN PHYTOREMEDIATION. (reference books) SCIENTIFIC ARTICLES WILL BE PROVIDED BY THE TEACHER AND DISCUSSED AT LESSONS.	2	BIO/05	-	20	-	-	Core compulsory activities	ITA
20401642-1 - MODULO 1 - VIGNOLI LEONARDO (syllabus) Cultural skills (Knowledge of:) The course offers the conceptual bases for (A) understanding the bases of population ecology (B) understanding the community ecology (C) understanding the behavioural ecology (D) understanding the macroecology (E) an evolutionary approach to the study of animal ecology. Methodological skills (Knowing how to perform:) acquire the critical thinking through readings and discussions, in order to correctly evaluate a research hypothesis, choose research tools and interpret results. SYLLABUS THE COURSE CONSISTS OF A PRELIMINARY MODULE OF LESSONS AND ONE OR TWO FINAL RESIDENTIAL STAGES IN A NATURAL ENVIRONMENT, INCLUDING BOTH THEORETICAL LESSONS AND SEVERAL FIELD PRACTICES CONCERNING ASPECTS OF POPULATION AND COMMUNITY ECOLOGY, HABITAT PREFERENCE AND RESOURCE PARTITIONING BY THE SPECIES. THE PRELIMINARY MODULE IS DEVOTED TO STUDY THE FOLLOWING SUBJECTS: (a) STRUCTURAL LEVELS OF ANIMAL DIVERSITY. (a) ANIMAL ADAPTATIONS TO THE ECOLOGICAL CHARACTERISTICS OF BIOMES. (b) ANIMAL COMMUNITY ECOLOGY: INTRA- AND INTER-SPECIFIC RELATIONSHIPS; EXAMPLES OF ANIMAL COMMUNITIES OF AQUATIC AND TERRESTRIAL HABITATS; QUALITATIVE AND QUANTITATIVES METHODS FOR ANALYSING ANIMAL COMMUNITY; DIVERSITY, EVENESS AND DOMINANCE, INDICES; (c) ANIMAL POPULATION ECOLOGY: STRUCTURE, DYNAMICS, REGULATION, AGE CLASSES, SEX-RATIO; ESTIMATION OF POPULATIONS SIZE AND DENSITY, CAPTURE AND RECAPTURE METHODS; (d) AUTOECOLOGY: RESEARCH METHODS AND DATA ANALYSES; DEFINITION OF ECOLOGICAL NICHE AND STUDY CASES: REPRODUCTIVE, TROPHIC, SPATIAL (HOME RANGE, TERRITORY), TEMPORAL (PHENOLOGY, LYFE CYCLES), NICHES. THE COURSE PROVIDES, IN ADDITION TO THE RESIDENTIAL STAGE (CA. 6 HOURS A DAY OF PRACTICES IN NATURE AND 2 HOURS A DAY OF LECTURES), ALSO 2-3 EXERCISES IN NATURE OF A SINGLE DAY, INTERVALED TO THE FRONTAL LESSONS IN THE FIRST MODULE. (reference books) NOTES AND POWER POINTS ARE PROVIDED BY THE TEACHER. THE FOLLOWING TEXTBOOKS HELP TO STUDY SOME ASPECTS OF THE PROGRAMME: - RICKLEFS R.E., 1997. ECOLOGIA. ZANICHELLI; - BOITANI L. & FULLER T.K. (EDS.), 2000. RESEARCH TECHNIQUES IN ANIMAL ECOLOGY. CONTROVERSIES AND CONSEQUENCES. COLUMBIA UNIVERSITY PRESS, N.Y.; - KREBS J.R. & DAVIES N.B., 2002. ECOLOGIA E COMPORTAMENTO ANIMALE. BOLLATI BORINGHIERI; - GOTELLI, N.J. AND A.M. ELLISON. 2004. A PRIMER OF ECOLOGICAL STATISTICS. SINAUER ASSOCIATES, INC., SUNDERLAND, MA.; - GOTELLI, N.J. 2008. A PRIMER OF ECOLOGY. 4TH EDITION. SINAUER ASSOCIATES, INC., SUNDERLAND, MA. - HENDERSON, P.A. 2003. PRACTICAL METHODS IN ECOLOGY. BLACKWELL SCIENCE LTD Students are provided with a document that lists for each lesson topic which textbook and which chapters are most relevant for the study, and for each topic it lists recent scientific papers for further study. Students are also provided with PDFs of lessons and of scientific papers suggested.	4	BIO/05	32	-	-	-	Core compulsory activities	ITA

SECOND YEAR

First semester

Course

Credits

Scientific Disciplinary Sector Code

Contact Hours

Exercise Hours

Laboratory Hours

Personal Study Hours

Type of Activity

Language

20401644 - ENVIRONMENTAL LAW (objectives)

- DE LEONARDIS FRANCESCO

IUS/10

Core compulsory activities

ITA

Optional group: OPZIONALI - (show)

20401076 - BIOTECNOLOGIE DEI MICRORGANISMI
20401076-2 - MODULO 2 - Derived from 20401076 BIOTECNOLOGIE DEI MICRORGANISMI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	2	CHIM/11	-	-	20	-	Related or supplementary learning activities	ITA
20401076-1 - MODULO 1 - Derived from 20401076 BIOTECNOLOGIE DEI MICRORGANISMI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	4	CHIM/11	32	-	-	-	Related or supplementary learning activities	ITA
20401221 - METODOLOGIE MOLECOLARI IN GENETICA E CITOGENETICA
20401282 - PHYSICAL CHEMISTRY FOR THE LIFE SCIENCE (objectives) THE MAJOR GOALS FOR THIS COURSE ARE CENTERED AROUND ACQUIRING A DEEP UNDERSTANDING OF THERMODYNAMIC AND KINETIC THEORIES, APPLIED TO BIOCHEMICAL PROBLEMS. THE COURSE WILL START BY THE RIGOROUS DEFINITION OF THERMODYNAMIC PRINCIPLES AND STATE FUNCTIONS, THEN THE STUDENTS WILL BE ABLE TO APPLY THESE AND RELATED CONCEPTS TO UNDERSTAND THE PHYSICO-CHEMICAL MECHANISMS OF THE MAIN BIOLOGICAL TRANSFORMATIONS. - Derived from 20401282 CHIMICA FISICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 BATTOCCHIO CHIARA (syllabus) PRINCIPI DELLA TERMODINAMICA. POTENZIALI TERMODINAMICI: ENERGIA INTERNA, ENTALPIA, ENTROPIA, ENERGIA LIBERA DI GIBBS. TERMODINAMICA DELLE SOLUZIONI: POTENZIALE CHIMICO, SOLUZIONI IDEALI, REALI ED ELETTROLITICHE. POTENZIALE ELETTROCHIMICO. PRESSIONE OSMOTICA. COSTANTE DI EQUILIBRIO. CINETICA CHIMICA. ELEMENTI DI CINETICA ENZIMATICA. STUDIO DI PROCESSI BIOCHIMICI COMPLESSI: TRASPORTO ATTRAVERSO LE MEMBRANE. ENZIMI. TRASFERIMENTO DI ELETTRONI NEI SISTEMI BIOLOGICI (reference books) PETER ATKINS, JULIO DE PAULA: CHIMICA FISICA BIOLOGICA (VOL.1). ED. ZANICHELLI	6	CHIM/02	48	-	-	-	Related or supplementary learning activities	ITA
20401283 - GENETICA UMANA
20401660 - CHIMICA ANALITICA
20401660-2 - MODULO 2 - Derived from 20401660 CHIMICA ANALITICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	2	CHIM/01	-	20	-	-	Related or supplementary learning activities	ITA
20401660-1 - MODULO 1 - Derived from 20401660 CHIMICA ANALITICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	4	CHIM/01	32	-	-	-	Related or supplementary learning activities	ITA
20401662 - PHARMACOLOGY (objectives) THE AIM OF THE COURSE IS TO PROVIDE STUDENTS WITH A SOUND KNOWLEDGE OF THE FOLLOWING TOPICS: 1) PHARMACOKINETICS AND PHARMACODYNAMICS OF THE MAIN CLASSES OF DRUGS; 2) ADVERSE DRUG REACTIONS AND DRUG-DRUG INTERACTIONS; 3) PRINCIPLES OF DRUG ACTION AT THE CELLULAR, SUBCELLULAR AND MOLECULAR LEVELS; 4) PRINCIPLES OF CLINICAL AND PRECLINICAL PHARMACOLOGY. - Derived from 20401662 FARMACOLOGIA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 TREZZA VIVIANA (syllabus) INTRODUZIONE: NATURA DEI FARMACI, FORME FARMACEUTICHE, CLASSIFICAZIONE DEI FARMACI. SPERIMENTAZIONE PRECLINICA E CLINICA. PRINCIPI DI FARMACOLOGIA GENERALE- FARMACOCINETICA: PROCESSI DI ASSORBIMENTO, DISTRIBUZIONE, BIOTRASFORMAZIONE ED ELIMINAZIONE DEI FARMACI. PRINCIPALI PARAMETRI FARMACOCINETICI. FARMACODINAMICA: MECCANISMI D’AZIONE NON RECETTORIALI E RECETTORIALI; RECETTORI DEI FARMACI E LORO CLASSIFICAZIONE; LEGAME RECETTORE-FARMACO E PROCESSI DI TRASDUZIONE DEL SEGNALE; AGONISTI ED ANTAGONISTI RECETTORIALI. NEUROTRASMETTITORI E NEUROMODULATORI. FARMACOLOGIA SPECIALE- MECCANISMI D'AZIONE, EFFETTI FARMACOLOGICI ED EFFETTI COLLATERALI DELLE PRINCIPALI CLASSI DI FARMACI: FARMACI ATTIVI A LIVELLO DEL SISTEMA NERVOSO AUTONOMO; FARMACI DEL SISTEMA NERVOSO CENTRALE; FARMACI DELL’APPARATO CARDIOVASCOLARE, DEL SANGUE E DEL RENE; FARMACI DELL'APPARATO RESPIRATORIO; FARMACI DELL'INFIAMMAZIONE; FARMACI DELL’APPARATO DIGERENTE; FARMACI ANTINEOPLASTICI; CHEMIOTERAPICI ANTIMICROBICI. PRINCIPI DI TOSSICOLOGIA (reference books) S.G. CELLA, DI GIULIO AM., GORIO A., SCAGLIONE F. FARMACOLOGIA GENERALE E SPECIALE PER LE LAUREE SANITARIE, PICCIN, 2010; F. ROSSI, V. CUOMO, C. RICCARDI “FARMACOLOGIA. PRINCIPI DI BASE ED APPLICAZIONI TERAPEUTICHE”, ED. MINERVA MEDICA, TORINO, 2005; KATZUNG B.C.: "FARMACOLOGIA GENERALE E CLINICA" ED. PICCIN, PADOVA, 2003. MATERIALE DIDATTICO FORNITO DAL DOCENTE. Power-point files of the lessons will be provided To get an appointment with the Professor, email to: viviana.trezza@uniroma3.it	6	BIO/14	48	-	-	-	Related or supplementary learning activities	ITA
20401664 - MICROBIAL GENETICS (objectives) TRAINING IN THE CRITICAL READING OF SCIENTIFIC PAPERS; REINFORCEMENT OF THE DISCIPLINE’S HISTORICAL-EPISTEMOLOGICAL FOUNDATION; KNOWLEDGE-BUILDING IN THEORETICAL, METHODOLOGICAL. AND TECHNICAL ASPECTS OF GENETIC SPERIMENTATION ON MICRO-ORGANISMS; REINFORCING OF MASTERY OF CRUCIAL ISSUES (BIOLOGICAL CYCLE; GENOME ORGANIZATION AND EXPRESSION; HEREDITARY AND EVOLUTIONARY MECHANISMS OF PHAGES, BACTERIA, AND ASCOMYCETES; TRAINING IN BASIC TECHNICAL AND METHODOLOGICAL SKILLS CONCERNING GENETIC EXPERIMENTATION ON MICRO-ORGANISMS (i.e. EXPERIMENTAL DATA COLLECTION, PRESENTATION, AND INTERPRETATION); TRAINING STUDENTS TO SELF-ASSESS KNOWLEDGE/SKILLS, AND TO ENGAGE IN SCIENTIFIC DEBATE. - Derived from 20401664 GENETICA DEI MICRORGANISMI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 CASALINO MARIA ASSUNTA, COZZI RENATA (syllabus) SONO PRESENTATI E DISCUSSI 10-15 ARTICOLI SCIENTIFICI CHE MARCANO LE TAPPE RILEVANTI DELL'ITINERARIO STORICO ED EPISTEMOLOGICO DI RICERCHE DEDICATE A DUE TEMATICHE CHE POSSONO VARIARE DI ANNO IN ANNO (AD ESEMPIO: ORIGINE DELLA MUTAZIONE SPONTANEA, ORIGINE ED EVOLUZIONE DEL CODICE GENETICO, REGOLAZIONE PER ATTENUAZIONE). GLI ARTICOLI PRESCELTI CONSENTONO DI TRATTARE ESTESAMENTE ARGOMENTI CRUCIALI CHE HANNO GODUTO DI CONTRIBUTI SIGNIFICATIVI GRAZIE ALLA RICERCA NEL SETTORE, QUALI LE BASI DELLA GENETICA MOLECOLARE, LA MUTAZIONE, I MECCANISMI FISICO-CHIMICI DELL'EREDITÀ, FISIOLOGIA E GENETICA DI BATTERIOFAGI, BATTERI E ASCOMICETI. (reference books) GLI ARTICOLI SCIENTIFICI OGGETTO DEL CORSO SONO DISTRIBUITI IN FOTOCOPIA. I TESTI CONSIGLIATI PER LA CONSULTAZIONE E L'APPROFONDIMENTO SONO DISPONIBILI PRESSO IL LABORATORIO: G.S. STENT "GENETICA MOLECOLARE" ZANICHELLI (1977), U.N. STREIPS, R.E. YASBIN "MODERN MICROBIAL GENETICS" WILEY-LISS (2002). I MATERIALI DI DOCUMENTAZIONE PER LE ATTIVITÀ DI LABORATORIO SONO DISTRIBUITI NEL CORSO DELLE ATTIVITÀ MEDESIME.	6	BIO/18	48	-	-	-	Related or supplementary learning activities	ITA
20401665 - MANAGEMENT AND PLANNING OF HISTORICAL GARDENS AND ARCHAEOLOGICAL SITES (objectives) STUDY THE RELATIONSHIP BETWEEN MAN & NATURE IN THE ANCIENT TIME. STUDY BIODETERIORATION RELATED TO THE VEGETATION IN THE ARCHAEOLOGICAL AREAS. ANALYSE HOW WAS THE PLANNING OF ARCHAEOLOGICAL PARKS IN ITALY AND DESCRIBE THE PROBLEMS OF MANAGEMENT. STUDY HISTORICAL PARKS, GIVING EXAMPLES FROM THE ASSYRO-BABYLONIANS, EGYPTIANS, GREEK-ROMANS, MEOIOEVAL TIMES TO MODERN AND CONTEMPORARY AGE. DESCRIBE THE PROBLEMS OF MANAGEMENTS OF HISTORICAL GARDENS. GIVE PRACTICAL FIELD EXAMPLES, VISITING AREAS SUCH AS COLOSSEUM AND HORTI FARNESIANI ON THE PALATINE, ARCHAEOLOGICAL AREAS IN THE APPIA ANTICA, AND OTHER HISTORICAL PARKS IN THE CENTRAL ITALY.
20401665-1 - MODULO 1 - CANEVA GIULIA	5	BIO/03	40	-	-	-	Related or supplementary learning activities	ITA
20401665-2 - MODULO 2 - CANEVA GIULIA	1	BIO/03	-	10	-	-	Related or supplementary learning activities	ITA
20401668 - ENVIRONMENTAL MICROBIOLOGY (objectives) THE MAIN AIMS OF THE COURSE ARE: 1) RECOGNIZE MAJOR GROUPS OF MICROORGANISMS AND UNDERSTAND FACTORS INFLUENCING THEIR ENVIRONMENTAL DISTRIBUTION AND INTERACTIONS WITH HIGHER ORGANISMS; 2) LEARN ABOUT ROLES PLAYED BY MICROBES IN SOIL FORMATION, MINERAL WEATHERING, CARBON AND NITROGEN CYCLING; 3) LEARN ABOUT CULTURE-BASED AND CULTURE-INDEPENDENT MICROBIOLOGICAL METHODS; 4) GAIN LITERACY IN CRITICAL READING AND ANALYSIS OF SCIENTIFIC LITERATURE IN THE FIELD OF ENVIRONMENTAL MICROBIOLOGY.
20401669 - EXPERIMENTAL MODELS IN BIOLOGY (objectives) THE COURSE PROVIDES BASICS CONCERNING THE EXPERIMENTAL MODELS MOST COMMONLY USED IN BIOLOGICAL RESEARCH.
20401669-2 - MODULO 2 - Derived from 20401669 MODELLI SPERIMENTALI IN BIOLOGIA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) LABORATORY PRACTICES (0.5 CFU) WILL BE FIXED TOGETHER WITH THE STUDENTS WITH THE AIM OF ACQUIRING NEW TECHNIQUES ON SOME EXPERIMENTAL MODELS WIDELY USED IN BIOLOGICAL RESEARCH (reference books) TEXTBOOKS AND OTHER EDUCATIONAL MATERIAL FOR HOMEWORKS WILL BE SUGGESTED TO LEARNERS DURING THE COURSE.	,5	BIO/09	-	-	5	-	Related or supplementary learning activities	ITA
20401669-1 - MODULO 1 - Derived from 20401669 MODELLI SPERIMENTALI IN BIOLOGIA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) THE COURSE (6 CFU) IS DIVIDED INTO TWO MAIN PARTS. THE FIRST ONE (5.5 CFU) IS AIMED AT DESCRIBING THE HISTORICAL AND NORMATIVE FRAMEWORK. THE SECOND ONE IS PLANNED TO FOCUS THE STUDY ON A VARIETY OF BOTH IN VITRO AND IN VIVO EXPERIMENTAL MODELS, WHOSE EMPLOYMENT IS USEFUL IN EITHER BIOLOGY APPLIED TO HUMAN HEALTH OR CELLULAR/MOLECULAR BIOLOGY. STARTING POINTS FOR DISCUSSIONS WILL BE PROVIDED, IN ORDER TO ENGAGE THE LEARNERS FOR THE WRITING OF A REPORT THAT WILL BE GOAL OF EXAMINATION. LABORATORY PRACTICES (0.5 CFU) WILL BE FIXED TOGETHER WITH THE STUDENTS WITH THE AIM OF ACQUIRING NEW TECHNIQUES ON SOME EXPERIMENTAL MODELS WIDELY USED IN BIOLOGICAL RESEARCH (reference books) TEXTBOOKS AND OTHER EDUCATIONAL MATERIAL FOR HOMEWORKS WILL BE SUGGESTED TO LEARNERS DURING THE COURSE.	5,5	BIO/09	44	-	-	-	Related or supplementary learning activities	ITA
20401674 - CARTOGRAPHY AND G.I.S. APPLIED TO ECOLOGY (objectives) TO PROVIDE THE THEORETICAL CONCEPTS AND PRACTICAL TOOLS IN GEOGRAPHY, CARTOGRAPHY, AND STATISTICAL ANALYSIS FOR ECOLOGICAL ADVANCES, THROUGH THE USE OF CASE STUDIES AND PRACTICAL APPLICATIONS.
20401674-1 - MODULO 1 - SALVATI LUCA (syllabus) 1) Relational databases2) Introduction to GIS3) Spatial data formats4) Digital cartography (reference books) Slides and scientific articles (class-disseminated).MUNAFÒ M. 2010. RAPPRESENTARE IL TERRITORIO E L’AMBIENTE. BONANNO, ROMA-ACIREALE (textbook).	5	BIO/03	40	-	-	-	Related or supplementary learning activities	ITA
20401674-2 - MODULO 2 - SALVATI LUCA (syllabus) 5) Introduction to historical cartography6) Remote sensing theory and practice7) Geo-statistics and spatial statistics. (reference books) Slides and selected papers, and the following textbook:MUNAFÒ M. 2010. RAPPRESENTARE IL TERRITORIO E L’AMBIENTE. BONANNO, ROMA-ACIREALE (parte 2).	1	BIO/03	-	10	-	-	Related or supplementary learning activities	ITA
20401782 - MOLECULAR BIOTECHNOLOGY (objectives) THE AIM OF THE COURSE IS TO PROVIDE METHODOLOGIES AND TECHNOLOGIES KNOWLEDGE OF BASIC AND APPLIED ADVANCED RESEARCH IN MOLECULAR BIOTECHNOLOGIES.
20401786 - GENERAL ENTOMOLOGY (objectives) THE MAIN FORMATIVE TARGETS ARE: 1) THE ACQUISITION OF A BASIC KNOWLEDGE ON MORPHOLOGY, ANATOMY, PHYSIOLOGY AND EVOLUTION OF THE MAIN INSECT GROUPS. 2) THE ACQUISITION OF BOTH THEORETICAL AND PRACTICAL KNOWLEDGE ON SYSTEMATICS AND CLASSIFICATION OF THE HEXAPODA. 3) THE CONSTRUCTION OF A SOLID CULTURAL BACKGROUND FOR AN ADVANCED DISCUSSION ON CAUSES AND EFFECTS OF THE AMAZING EVOLUTIONARY SUCCESS AND DIVERSITY OF INSECTS AND ON THEIR IMPORTANCE IN BASIC AND APPLIED STUDIES. 4) THE ACQUISITION OF THE TOOLS FOR THE INSECT TAXONOMIC IDENTIFICATION, EXPECIALLY FOR THOSE ORDERS AND FAMILIES PRESENT IN THE ITALIAN FAUNA. 5) TO STIMULATE THE CURIOSITY AND THE ABILITY OF CRITICALLY OBSERVE THE NATURE. 6) THE SELF-EVALUATION BY THE STUDENT OF THE COMPETENCE WHITIN THE ANIMAL BIOLOGY, AND IN PARTICULAR IN THE ENTOMOLOGY.
20401787 - ETHNOBOTANY AND ETHNOZOOLOGY (objectives) ANALYSIS OF ECOLOGICAL AND CULTURAL RELATIONS BETWEEN HUMANS AND LIVING BEINGS, THROUGH AN HISTORICAL AND GEOGRAPHIC SURVEY AT DIFFERENT LEVELS OF CIVILIZATION. PERSPECTIVES OF THE RECOVERY OF POPULAR TRADITIONS.
20401787-2 - MODULO 2	1	BIO/05	-	10	-	-	Related or supplementary learning activities	ITA
20401787-1 - MODULO 1	5	BIO/03	40	-	-	-	Related or supplementary learning activities	ITA
20401788 - STRATEGIC ENVIRONMENTAL ASSESSMENT (objectives) To provide the basics in terms of technical, legal, scientific and cultural issues on environmental assessment tools, with particular reference to the Environmental Impact Assessment, the Strategic Environmental Assessment, the assessment of impacts, the indicators for the monitoring and reporting of environmental . The knowledge acquired by the students, integrated with the content of other courses within the degree course (Technical Cartographic and GIS, Statistics, Applied Ecology, Management of Ecosystems, Biodiversity, etc..) contributes to develop professional figures in environmental monitoring.
20401788-2 - MODULO 2	3	BIO/05	24	-	-	-	Related or supplementary learning activities	ITA
20401788-1 - MODULO 1	3	BIO/03	24	-	-	-	Related or supplementary learning activities	ITA
20401875 - METHODS AND TECHNIQUES OF EDUCATION AND PROMOTION OF NATURALISTIC AND ENVIRONMENTAL ISSUES (objectives) Students’ grow in knowledge, skills and abilities in order to become a professional in the fields of education and naturalistic and environmental dissemination. Making students aware of the professions related to dissemination and education in the field of nature and environment as potential job opportunities for specialists of management and protection of ecosystems.
20401875-2 - MODULO 2	3	BIO/07	24	-	-	-	Related or supplementary learning activities	ITA
20401875-1 - MODULO 1	3	BIO/07	24	-	-	-	Related or supplementary learning activities	ITA
20401992 - MICROBIAL BIOTECHNOLOGY LABORATORY (objectives) THE MAIN AIMS OF THE COURSE ARE: A) ACQUISITION OF APPROPRIATE METODOLOGIES AND LANGUAGES FOR THE ISOLATION, OBSERVATION AND DESCRIPTION OF INDUSTRIAL MICROORGANISMS B) ACQUISITION OF THE BASIC KNOWLEDGE FOR THE DRAFTING AND EXECUTION OF AN EXPERIMENTAL PROTOCOL
20402205 - MEDICAL PARASITOLOGY (objectives) TO PROVIDE STUDENTS WITH LEARNIG COMPETENCE IN THE FIELD OF GENERAL AND APPLIED PARASITOLOGY, INCLUDING A NUMBER OF LABORATORY TECHNIQUES NECESSARY FOR THE STUDY AND DIAGNOSIS OF THE MAIN PARASITIC DISEASES. - Derived from 20402205 PARASSITOLOGIA MEDICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 GRADONI LUIGI (syllabus) GENERAL CONCEPTS AND LIFE CYCLES OF THE MAIN HUMAN PARASITES TERMINOLOGY AND DEFINITIONS IN GENERAL PARASITOLOGY CLASSIFICATION OF HUMAN PARASITES (PROTOZOA, PLATELMINTHS, NEMATODES AND ARTHROPODS) MORPHOLOGICAL IDENTIFICATION OF PARASITES BIOCHEMICAL AND MOLECULAR TECHNIQUES APPLIED TO PARASITE IDENTIFICATION AND SYSTEMATICS TRANSMISSION PATTERNS THROUGH VECTORS: TRYPANOSOMATIDS, PLASMODIA, BABESIA, FILARIAL WORMS, SCHISTOSOMES TRANSMISSION PATTERNS THROUGH INGESTION: GIARDIA, AMOEBA, TOXOPLASMA, CRYPTOSPORIDIUM, OPISTHORCHIS, TAPEWORMS, TRICHINELLA, TOXOCARA, PINWORMS OTHER TRANSMISSION PATTERS: STRONGYLOIDES IMMUNITY TO PARASITES AND PARASITE’S EVASION PARASITIC DISEASES TERMINOLOGY AND DEFINITIONS IN EPIDEMIOLOGY, PATHOGENESIS, CLINICAL FEATURES, DIAGNOSIS AND TREATMENT MAJOR PARASITIC DISEASES ENDEMIC IN ITALY: LEISHMANIASIS, GIARDIASIS, TOXOPLASMOSIS, CYSTICERCOSIS, ECHINOCOCCOSIS/HYDATIDOSIS, TRICHINELLOSIS, TOXOCARIASIS, DIROFILARIASIS, OXYURIASIS, PEDICULOSIS MAJOR PARASITIC DISEASES IMPORTED INTO ITALY: AFRICAN TRYPANOSOMIASIS (SLEEPING SICKNESS), AMERICAN TRYPANOSOMIASIS (CHAGAS DISEASE), AMEBIASIS, MALARIA, SCHISTOSOMIASIS (reference books) DE CARNERI – PARASSITOLOGIA MEDICA E DIAGNOSTICA PARASSITOLOGICA – CASA EDITRICE AMBROSIANA, 2013 GABRIELLA CANCRINI – PARASSITOLOGIA MEDICA ILLUSTRATA – LOMBARDO EDITORE, 2012	6	MED/07	48	-	-	-	Related or supplementary learning activities	ITA
22402256 - EVOLUTIONARY PARASITOLOGY (objectives) Offering the students a new perspective in the study of parasitology, by means of an ecological- evolutionary and comparative approach. The intimate and intricate nature of the association between host and parasite, has traditionally been studied by giving emphasis on its pathogeniticy for non human animal and human hosts. In contrast, this course offers the student the opportunity to deepen topics such as adaptive strategies of parasitic life-style, the impact of parasitism on the community structure or else the role of a parasite in the trophic energy transfer in the community. Emphasis will be given to the host as key element in the parasite environment and, as such, its important role as a selective pressure. The student will be provided with a dynamic course made of lectures, workshops and tutorials on taxa parasites
22402257 - GENERAL AND APPLIED ANIMAL VIROLOGY (objectives) OBJECTIVS: TO ACQUIRE A SOLID FOUNDATION IN ANIMAL VIROLOGY AND THEIR APPLICATION.
20402025 - Bioindication and Environmental Monitoring (objectives) Acquisition of specific knowledge on bioindication and its applications, particularly with regard to plant and animal organisms used as biological indicators of the environmental status. Knowledge of the experimental methods and data processing for the environmental monitoring.
20402506 - MOLECULAR BASIS OF PLANT-ENVIRONMENT INTERACTION (objectives) TO INCREASE KNOWLEDGE CONCERNING FUNDAMENTAL PROCESSES UNDERLYING PLANT ACCLIMATION TO DIFFERENT ENVIRONMENTAL STRESSES, USEFUL IN DEVELOPING NEW STRATEGIES FOR IMPROVING CROP PRODUCTIVITY UNDER CHANGING ENVIRONMENTAL CONDITIONS IN THE CONTEXT OF SUSTAINABLE AGRICULTURE. BASIC KNOWLEDGE WILL BE PROVIDED ON PLANT EMPLOYMENT IN PHARMACOLOGICAL, NUTRACEUTICAL AND ENVIRONMENTAL FIELD.
20402506-2 - MODULO 2 - CONA ALESSANDRA (syllabus) Practical laboratoriesDetermination of amine oxidase enzyme activity and hydrogen peroxide production through spectrophotometric methods on maize and chickpea plant extracts.Observation under light microscopy of tissue-specific gene expression of copper amine oxidases (AtCuAO) after GUS-staining using 5-day-old PromAtCuAO-GUS-GFP Arabidopsis transgenic seedlings, fixed in 90% acetone and washed in phosphate buffer. (reference books) Introductory material and experimental procedure provided by the teacherThe Prof. receives every day by appointment via email: alessandra.cona@uniroma3.it	1	BIO/04	-	10	-	-	Related or supplementary learning activities	ITA
20402506-1 - MODULO 1 - CONA ALESSANDRA (syllabus) SIGNAL PERCEPTION AND TRANSDUCTION PATHWAYS IN PLANT CELLS: RECEPTORS, MEDIATORS AND MODALITY OF TRANSDUCTION. SIGNALING PATHWAYS UPON HORMONE OR LIGHT PERCEPTION. CELL WALL AT THE INTERFACE BETWEEN INTRACELLULAR AND EXTRACELLULAR ENVIRONMENT: CELL SURFACE SENSORS AND RECEPTORS. ROLE OF REACTIVE OXYGEN SPECIES IN SIGNAL TRANSDUCTION. PHENOTYPIC PLASTICITY IN RESPONSES TO ABIOTIC STRESSES (DROUGHT, FLOODING, SALT STRESS, HIGH AND LOW TEMPERATURE, HIGH LIGHT). SECONDARY METABOLISM AND DEFENCE STRATEGY AGAINST WOUNDING OR PATHOGEN ATTACK. INNATE IMMUNITY AND EFFECTOR TRIGGERED IMMUNITY. LOCAL AND SYSTEMIC DEFENCE RESPONSES. PLANT COMPOUNDS AS SOURCE OF DRUGS, NUTRACEUTICAL FOOD OR NATURAL HERBICIDES. BASIC KNOWLEDGE IN PHYTOREMEDIATION. (reference books) SCIENTIFIC ARTICLES WILL BE PROVIDED BY THE TEACHER AND DISCUSSED AT LESSONS.The professor receives every day by appointment via e-mail: alessandra.cona@uniroma3.it	5	BIO/04	40	-	-	-	Related or supplementary learning activities	ITA
20402507 - Diversity and Ecology of the Soil Fauna
20402507-1 - MODULO 1 - DI GIULIO ANDREA (syllabus) 1. General Introduction to the soil ecosystem. Definition of the soil and its functions. Factors and pedogenetic processes. Profile and composition of the soil. Physical and chemical characteristics. Cycles of nutrients in the soil. Organic matter decomposition and mineralization. Case study of the dead wood.2. Edaphic biodiversity. Micro, meso and macro-ecological networks at ground level. Viruses and soil microorganisms and their interaction with the soil fauna. Microflora and vegetation. Soil fauna: main adaptations to life in the soil. Functional groups and food webs. Edaphic zoocoenoses present in different types of terrestrial ecosystems and their interactions with other biological forms.3. Main soil fauna groups: Protozoa, Rotifera, Platyhelminthes, Nematodes, Tardigrades, Molluscs, Annelids, Arthropods, Cordata. Morphological, functional, physiological, behavioral and ecological adaptations to life in the soil. (reference books) Menta C., 2008. Guida alla conoscenza della biologia e dell'ecologia del suolo. A. Perdisa EditoreParisi V., 1974. Biologia e ecologia del suolo. Boringhieri, Torino.Office Hours: every day of the week by appointment by email (andrea.digiulio@uniroma3.it)	4	BIO/05	32	-	-	-	Related or supplementary learning activities	ITA
20402507-2 - MODULO 2 - DI GIULIO ANDREA (syllabus) 4. Methods for studying soil fauna. Sampling methods. Extraction. Identification with use of dichotomous or interactive keys. Methods and tools for morphological, genetic and functional analyses.5. Use of soil biodiversity in environmental monitoring. Biological and ecotoxicological indices. Bioremediation and environmental recovery. Management and protection of soil fauna. Applications of soil fauna in agriculture and natural resource management.6. The course also includes practical lessons in the laboratory and in the field. During these classes, observations on the diversity of soil fauna in natural ecosystems will be conducted, illustrating methods of sampling and identification. (reference books) Menta C., 2008. Guida alla conoscenza della biologia e dell'ecologia del suolo. A. Perdisa EditoreParisi V., 1974. Biologia e ecologia del suolo. Boringhieri, Torino.Office Hours: every day of the week by appointment by email (andrea.digiulio@uniroma3.it)	2	BIO/05	-	20	-	-	Related or supplementary learning activities	ITA
20402509 - ECOLOGY AND MANAGEMENT OF COASTAL ECOSYSTEMS (objectives) MAJOR GOALS OF THIS COURSE ARE: TO ACQUIRE AN APPROPRIATE KNOWLEDGE OF THE BIODIVERSITY AND OF GENERAL PRINCIPLES OF THE ECOLOGY OF COASTAL ECOSYSTEMS AND THEIR RELATIONSHIP WITH OTHER ECOLOGICAL BRANCHES. OTHER GOAL OF THIS COURSE IS THE GROWTH OF A THOROUGH INTEREST TO ECOLOGICAL PROBLEMS DISCUSSING THE RELATIONSHIP BETWEEN MAN AND NATURE FOCUSING IN THE COASTAL ENVIRONMENT. THE COURSE IS ALSO INTENDED TO DEVELOP BASIC INSIGHTS FOR THE ACQUISITION, ORGANIZATION AND INTERPRETATION OF ECOLOGICAL DATA RECORDED IN COASTAL ECOSYSTEMS.
20402510 - INLAND AND MARINE WATER ECOLOGY (objectives) The main aim is to provide a solid knowledge on both abiotic and biotic features of ecological processes considered to be common in aquatic systems. A second goal is to develop identification ability of the main aquatic species of Mediterranean systems by a comparative analysis of the different life strategies and colonization patterns of extreme habitats, and the possibility to origin more and more structured multi-species assemblanges to start ecological series. During the course, it will be introduced methods and tools to perform aquatic investigations. Students will receive information to design and execute sampling sessions on plankton, benthos e nekton, to analyze and show findings. Finally students will learn to develop applicative aspects of work in diverse issues in the field of aquatic biomonitoring and hydrobiology.
20402510-1 - MODULO 1 - SCALICI MASSIMILIANO (syllabus) Cultural competences (Knowledge of:) The teaching aims to provide students with basic knowledge related to the evolution of the different ecological components, to assess the degree of functional adaptation to the habitat.Methodological skills (Know how to perform:) acquire and use experimental data related to hydrobiological studiesTeaching program:1) INTRODUCTORY LIMNOLOGY AND OCEANOGRAPHY: PHYSICAL-CHEMICAL PROPERTIES OF WATER (TEMPERATURE-DENSITY, TRANSPARENCY, SALT COMPOSITION, SALINITY, CONDUCTIVITY, HARDNESS); WATER BODY THERMAL BALANCE; AQUATIC MOVEMENTS (CURRENTS, TIDE, SEICHE); DISSOLVED OXYGEN AND REGULATING FACTORS; CARBON DIOXIDE, BICARBONATE, CARBONATE, BUFFER SYSTEM, MINERAL ACIDITY AND ALKALINITY; NUTRIENT CYCLES; ORGANIC MATTER, TOTAL SOLIDS, SUSPENDED MATERIAL, SEDIMENTS, BOD AND COD.2) AQUATIC LIFE: PLANCTON, NECTON E BENTHOS; CLASSIFICATION, METABOLISM AND LIFE CYCLES, COLLECTION METHODS AND TOOLS, ABUNDANCE AND BIOMASS ASSESSMENT; WATER COLUMN AND SEDIMENT ECOLOGY: PRIMARY PRODUCTION, SCRAPERS, SHREDDERS, AND SCAVENGERS: ENERGETIC FLOW IN FOOD PYRAMIDS AND WEBS; EXAMPLES OF SEA, COASTAL, LACUSTRINE, AND RIVER SYSTEMS (reference books) Bettinetti R., G. Crosa, S. Galassi. 2007. Ecologia delle acque interne. Edizioni CittàStudi.Cognetti G., Sarà M., Magazzù G. - Biologia Marina. Edizioni Calderini, Roma, 1999. 596 pagine.Notes and exercises will be providedProfessor receives every day from 17.00 to 19.00 by appointment via email:massimiliano.scalici@uniroma3.it	5	BIO/07	40	-	-	-	Related or supplementary learning activities	ITA
20402510-2 - MODULO 2 - SCALICI MASSIMILIANO (syllabus) Cultural competences (Knowledge of:) The teaching aims to provide students with basic knowledge related to the evolution of the different ecological components, to assess the degree of functional adaptation to the habitat.Methodological skills (Know how to perform:) acquire and use experimental data related to hydrobiological studiesTeaching program:1) INTRODUCTORY LIMNOLOGY AND OCEANOGRAPHY: PHYSICAL-CHEMICAL PROPERTIES OF WATER (TEMPERATURE-DENSITY, TRANSPARENCY, SALT COMPOSITION, SALINITY, CONDUCTIVITY, HARDNESS); WATER BODY THERMAL BALANCE; AQUATIC MOVEMENTS (CURRENTS, TIDE, SEICHE); DISSOLVED OXYGEN AND REGULATING FACTORS; CARBON DIOXIDE, BICARBONATE, CARBONATE, BUFFER SYSTEM, MINERAL ACIDITY AND ALKALINITY; NUTRIENT CYCLES; ORGANIC MATTER, TOTAL SOLIDS, SUSPENDED MATERIAL, SEDIMENTS, BOD AND COD.2) AQUATIC LIFE: PLANCTON, NECTON E BENTHOS; CLASSIFICATION, METABOLISM AND LIFE CYCLES, COLLECTION METHODS AND TOOLS, ABUNDANCE AND BIOMASS ASSESSMENT; WATER COLUMN AND SEDIMENT ECOLOGY: PRIMARY PRODUCTION, SCRAPERS, SHREDDERS, AND SCAVENGERS: ENERGETIC FLOW IN FOOD PYRAMIDS AND WEBS; EXAMPLES OF SEA, COASTAL, LACUSTRINE, AND RIVER SYSTEMS (reference books) Bettinetti R., G. Crosa, S. Galassi. 2007. Ecologia delle acque interne. Edizioni CittàStudi.Cognetti G., Sarà M., Magazzù G. - Biologia Marina. Edizioni Calderini, Roma, 1999. 596 pagine.Notes and exercises will be providedProfessor receives every day from 17.00 to 19.00 by appointment via email:massimiliano.scalici@uniroma3.it	1	BIO/07	-	10	-	-	Related or supplementary learning activities	ITA
20402511 - LABORATORY OF ELECTRON AND ION BEAM MICROSCOPY APPLIED TO BIOLOGICAL SYSTEMS (objectives) THE COURSE AIMS TO PROVIDE THE STUDENT WITH BASIC KNOWLEDGE AND TECHNICAL SKILLS IN ORDER TO APPROACH THE STUDY OF BIOLOGICAL SPECIMENS BY ULTRASTRUCTURAL MORFOLOGICAL METHODOLOGIES. MAIN OBJECTIVES INCLUDE LEARNING AND APPLYING:1) BASIC PRINCIPLES OF ELECTRON MICROSCOPY; 2) METHODOLOGIES OF SAMPLE PREPARATION (PROKARYOTES AND EUKARYOTES) FOR ULTRASTRUCTURAL ANALYSIS; 3) USAGE OF DEVICES FOR ULTRASTRUCTURAL INVESTIGATION (SCNANING, TRANSMISSION AND FOCUSING ION BEAM MICROSCOPY); 3) SOFTWARE FOR MICROSCOPIC IMAGE CAPTURING AND PROCESSING 4) QUALITATIVE INTERPRETATION AND QUANTITATIVE ANALYSIS OF ULTRASTRUCTURAL DATA. THE STUDENT WILL BE ABLE TO AUTONOMOUSLY CHOOSE AND ADJUST EXPERIMENTAL PROTOCOLS, SUITED TO DIFFERENT SAMPLE TYPES AND TO THE OBJECTIVE OF THE STUDY. KNOWLEDGE ACQUIRED DURING THE COURSE WILL ALLOW THE STUDENT TO CRITICALLY ANALYZE MORPHOLOGICAL RESULTS IN A FUNCTIONAL CONTEXT.
20402512 - METHODS AND TECHNIQUES IN VEGETATION ECOLOGY (objectives) MAJOR GOALS OF THIS COURSE ARE THE ACQUISITION OF KNOWLEDGE ON THE MAIN METHODS AND TECHNIQUES FOR THE STUDY OF VEGETATION: - ACQUIRE THE MASTERY OF THE STUDY METHODS OF VEGETATION; - INCREASE THE ABILITY TO INTERPRETING THE NATURAL AND ARTIFICIAL PHENOMENA WITH SPECIAL ATTENTION TO THE MECHANISMS OF TRANSFORMATION OF PLANT LANDSCAPES; - DEVELOP THE CAPACITY TO APPLICATION OF MOST APPROPRIATE METHODS FOR MONITORING OF THE PLANT COMMUNITIES FOR CONSERVATION AND MANAGEMENT PURPOSES; - INCREASE THE POSSIBILITIES OF INTERPRETATION OF EXPERIMENTAL DATA AND UNDERSTANDING OF SCIENTIFIC ARTICLES IN THE FIELDS OF PLANT ECOLOGY, GEOBOTANY AND APPLIED ECOLOGY.
20402519 - APPLIED CELLULAR NEUROBIOLOGY (objectives) THE AIMS OF THIS COURSE ARE: TO GAIN KNOWLEDGE OF THE SPECIALIZED CELLULAR ARCHITECTURE OF GLIA AND NEURONS; TO DEEPEN THE KNOWLEDGE OF CELLULAR AND MOLECULAR MECHANISMS INVOLVED IN CELL COMMUNICATION, SPECIAL EMPHASIS WILL BE GIVEN TO NITRIC OXIDE-REGULATED PATHWAYS. IN THIS COURSE STUDENTS CAN USE STATE OF THE ART EQUIPMENT AND LEARN CURRENT TECHNIQUES EMPLOYED IN CELL BIOLOGY RESEARCH LABS. MOREOVER STUDENTS ARE ALLOWED TO CRITICALLY DISCUSS THE SCIENTIFIC LITERATURE IN THE FIELD OF CELL BIOLOGY.
20402520 - PLANT BIOTECHNOLOGY FOR THE GENETIC IMPROVEMENT OF FOOD CROPS (objectives) THIS COURSE WILL PROVIDE STUDENTS WITH AN IN-DEPTH KNOWLEDGE OF PLANT TRANSFORMATION TECHNIQUES AND PLANT BIOTECHNOLOGY APPLICATIONS WITHIN AGRICULTURE AND PRODUCTION OF NEW MOLECULES. THIS COURSE WILL ALSO GIVE EDUCATION ON EMERGING TECHNOLOGIES, SUCH AS TRANSCRIPTOMICS, PROTEOMICS, METABOLOMICS, AND WILL DESCRIBE THEIR IMPORTANCE IN PLANT BIOTECHNOLOGY RESEARCH. ANOTHER IMPORTANT AIM OF THE COURSE IS TO PREPARE STUDENTS TO CONDUCT LABORATORY WORK AND RESEARCH IN THE SECTORS OF PLANT BIOTECHNOLOGY AND FOOD INDUSTRY, AS WELL AS TO CRITICALLY ANALYZE THE SCIENTIFIC INFORMATION
20402521 - MOLECULAR ENDOCRINOLOGY (objectives) ENDOCRINOLOGY IS USUALLY TAUGHT AT THE END OF STANDARD PHYSIOLOGY COURSES, BECAUSE THE ENDOCRINE SYSTEM REGULATES ALL THE OTHER ORGAN SYSTEMS. IN THIS RESPECT, LEARNING ABOUT ENDOCRINE SYSTEM HAS THE ADDED CHALLENGE OF INTEGRATING STUDENT KNOWLEDGE OF HORMONES AND THEIR ACTIONS WITH THE GENERAL FUNCTION OF A SPECIFIC ORGAN SYSTEM. THE MAIN OBJECTIVES OF THIS COURSE ARE TO ALLOW THE STUDENT TO GAIN A FOUNDATION OF KNOWLEDGE ABOUT THE ENDOCRINE SYSTEM AND INTEGRATIVE PHYSIOLOGY, TO BECOME REFINED IN THE CRITICAL ANALYSIS OF SCIENTIFIC PAPERS RELATED TO ENDOCRINE PHYSIOLOGY, TO DEVELOP PROBLEM SOLVING AND PUBLIC SPEAKING TECHNIQUES.
20402521-1 - MODULO 1 - Derived from 20402521 ENDOCRINOLOGIA MOLECOLARE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) INTRODUCTION TO ENDOCRINOLOGY (1 CFU) HISTORY, CHEMICAL NATURE OF HORMONES, EVOLUTION OF CHEMICAL SIGNALS. ENDOCRINE GLANDS, HORMONE SYNTHESIS AND RELEASE (ENDOCRINE, AUTOCRINE, PARACRINE, AND INTRACRINE ACTIONS, HORMONAL RHYTMS) MECHANISMS OF HORMONE ACTIONS (SIGNALLING FROM MEMBRANE AND INTRACELLULAR RECEPTORS)THE ENDOCRINE SYSTEM AND INTEGRATIVE PHYSIOLOGY (3 CFU) REPRODUCTIVE ENDOCRINOLOGY (FETAL GROWTH, PREGNANCY, MATERNAL ADAPTATION TO PREGNANCY)GROWTH (GROWTH FACTORS AND ONCOGENES IN FETAL GROWTH, POSTNATAL GROWTH, PUBERTY, HORMONESAND THE GENDER/SEX DIFFERENCES)AGEING (THEORIES, HORMONE REPLACEMENT THERAPIES, GERIATRIC ENDOCRINOLOGY) METABOLIC ENDOCRINOLOGY (REGULATION OF FOOD UPTAKE, REGULATION OF DIGESTIVE PROCESSES, OBESITY)HORMONES AND ENVIRONMENTAL INJURIES (1 CFU) STRESS ADAPTATION ENVIRONMENTAL ENDOCRINE DISRUPTORS DISORDERS OF THE ENDOCRINOLOGY SYSTEM (CELL GROWTH AND CANCER)CRITICAL ANALYSIS OF SCIENTIFIC LITERATURE (1 CFU) (reference books) SCIENTIFIC PUBLICATIONS WILL BE SUPPLIED IN THE CLASSROOM.	5,5	BIO/09	44	-	-	-	Related or supplementary learning activities	ITA
20402521-2 - MODULO 2 - Derived from 20402521 ENDOCRINOLOGIA MOLECOLARE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	,5	BIO/09	-	5	-	-	Related or supplementary learning activities	ITA
20402522 - DEVELOPMENTAL NEUROBIOLOGY (objectives) THE MAIN GOAL IS TO PROVIDE ADVANCED KNOWLEDGE IN DEVELOPMENTAL BIOLOGY, WITH SPECIAL REFERENCE TO THE NERVOUS SYSTEM. THE CELLULAR AND MOLECULAR MECHANISMS UNDERLYING NERVOUS TISSUE DIFFERENTIATION AND MORPHOGENESIS WILL BE ADDRESSED IN DIFFERENT IN VIVO MODELS. LIFE-LONG FUNCTIONAL IMPLICATIONS OF NEUROGENESIS AND PLASTICITY WILL BE EMPHASIZED. THE STUDENT WILL BE ABLE TO: 1) DESCRIBE DEVELOPMENTAL PROCESSES OF INVERTEBRATE AND VERTEBRATE NERVOUS SYSTEM; 2) RECOGNISE MOLECULAR PATHWAYS DIRECTING STEM CELLS TOWARDS NEURONAL/GLIAL CELL DIFFERENTIATION; 3) CORRELATE ONTOGENETIC ABNORMALITIES WITH SPECIFIC NEUROLOGICAL DISTURBANCES, INCLUDING INFANTILE DISEASES AND AGE-RELATED NEURODEGENERATION.
20402523 - MOLECULAR AND CELLULAR PHYSIOLOGY (objectives) ON THE BASIS OF THE MOST RECENT SCIENTIFIC LITERATURE, THE COURSE IS AIMED TO ALLOW THE STUDENTS TO UNDERSTAND SOME ASPECTS OF THE REGULATION OF CELLULAR FUNCTIONS

Second semester

Course

Credits

Scientific Disciplinary Sector Code

Contact Hours

Exercise Hours

Laboratory Hours

Personal Study Hours

Type of Activity

Language

20401781 - WILDLIFE MANAGEMENT (objectives)

- BATTISTI CORRADO

BIO/07

Core compulsory activities

ITA

Optional group: OPZIONALI - (show)

20401076 - BIOTECNOLOGIE DEI MICRORGANISMI
20401081 - ETHOLOGY AND ANIMAL BEHAVIOUR (objectives) PROVIDING STUDENTS WITH CONCEPTUAL BASIS FOR: (a) UNDERSTANDING BIOLOGICAL BASIS OF BEHAVIOR (b) UNDERSTANDING BEHAVIOR AS AN EMERGENT PROPERTY OF THE SYSTEM “ORGANISM” (c) AN EVOLUTIONARY APPROACH TO THE STUDY OF BEHAVIOR. PROMPTING STUDENTS’ CRITICAL THINKING BY MEANS OF APPROPRIATE READINGS AND DISCUSSIONS. THEREFORE STUDENTS WILL BE GIVEN TOOLS TO CORRECTLY EVALUATE A SCIENTIFIC HYPOTHESIS, CHOOSE APPROPRIATE TOOLS OF INVESTIGATION AND INTERPRET RESULTS. - CAROSI MONICA (syllabus) Cultural skills (Knowledge of:) The course offers the conceptual bases for (A) understanding the biological bases of behaviour (B) understanding behaviour as an emergent property of the organism (C) an evolutionary approach to the study of behaviour . Methodological skills (Knowing how to perform:) acquire the critical thinking through readings and discussions, in order to correctly evaluate a research hypothesis, choose research tools and interpret results. SYLLABUS Ethology: historical outline. Classic and operant conditioning. The three Nobel awards, founders of modern ethology: K. Lorenz, K. Von Frisch, and N. Tinbergen. Sociobiology and behavioral ecology. The evolutionary approach to the study of behaviour. Levels of analysis in the study of behaviour: questions on “how” and “why”. The study of causation and ontogenesis (proximate causes), survival value and evolution (ultimate causes). (1) Behavioural control. Exogenous factors and endogenous factors. Sensory filtering. Stimuli and signals. Fixed action patterns, evocative stimuli, innate triggering mechanism. Biorhythms. The biological clock. The hormonal state. The behavioural decision: the motivation. Spatial orientation. Compasses. The olfactory map. (2) Ontogenesis of behaviour. Role of genes and the environment. Embryology and behaviour: pre-natal ontogeny. Embryonic development of motility, sensitivity and sensory-motor sequences. Neurogenesis. Embryo learning. Postnatal ontogenesis. Behavioural endocrinology. The interactive theory of development, the organisational-activational hypothesis: development organisation, sexualisation of the brain, neural activation. Pre and post-natal learning. Imprinting and hormonal control of imprinting. Non-associative, associative, and complex learning. Behavioural control: nervous system and hormonal system. (3) The adaptive value of behaviour. The comparative approach to the study of behaviour. Signal evolution and communication. Communication: definitions, honest communication and deception. Ritualisation. Natural and artificial selection. Hybridisation between lines. Behavioural characters and strategies. Optimal strategies and evolutionarily stable strategies. Predatory and anti-predatory strategies: the arms race. Mimicry. Reproductive and social behaviour. Optimal strategies, fitness and reproductive success. Sexuality and innovation. Sexual selection: partner choice and competition. Sexual selection and sexual dimorphism. Conflict strategies between sexes. Differential reproductive success of females and males. Parental investment. Mating systems and social life. Sociality and group life: costs and benefits of socializing; the kin selection; altruism and evolution. Game theory. (reference books) RECOMMENDED TEXTBOOKS: - Alcock, J. 2007. Etologia, un approccio evolutivo. Zanichelli - Manning, A. e Stamp Dawkins, M. 2003. Il comportamento animale. Bollati Boringhieri. - Krebs J.R. e Davies N.B. 2002. Ecologia e comportamento animale. Bollati Boringhieri TEXTBOOKS FOR FURTHER READINGS: - Bolhuis, J.J. & Giraldeau, l. 2005. The behavior of animals: mechanisms, function and evolution. - Campan, R. & Scapini, F. 2004. Etologia. Zanichelli - Nelson, N.J. 2002. An introduction to behavioral endocrinology. Sinauer Associates, Sunderland - Andersson, M 1994. Sexual selection. Princeton University Press - Mainardi, D. 1992. Dizionario di etologia. Einaudi - Martin, P. & Bateson, P. 2003. La misurazione del comportamento. Una guida introduttiva. Liguori editore All textbooks can be found in the library Students are provided with a document that lists for each lesson topic which textbook and which chapters are most relevant for the study, and for each topic it lists recent scientific papers for further study. Students are also provided with PDFs of lessons and of scientific papers suggested. The professor receives every day from 9.00 to 10.00 by appointment via email: monica.carosi@uniroma3.it	6	BIO/05	48	-	-	-	Related or supplementary learning activities	ITA
20401221 - METODOLOGIE MOLECOLARI IN GENETICA E CITOGENETICA
20401221-2 - MODULO 2 - Derived from 20401221 METODOLOGIE MOLECOLARI IN GENETICA E CITOGENETICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	3	BIO/18	-	-	30	-	Related or supplementary learning activities	ITA
20401221-1 - MODULO 1 - Derived from 20401221 METODOLOGIE MOLECOLARI IN GENETICA E CITOGENETICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	3	BIO/18	24	-	-	-	Related or supplementary learning activities	ITA
20401283 - GENETICA UMANA
20401283-2 - MODULO 2 - Derived from 20401283 GENETICA UMANA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	1	BIO/18	-	10	-	-	Related or supplementary learning activities	ITA
20401283-1 - MODULO 1 - Derived from 20401283 GENETICA UMANA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	5	BIO/18	40	-	-	-	Related or supplementary learning activities	ITA
20401653 - BIOCHEMISTRY AND MOLECULAR CLINICAL BIOLOGY (objectives) Main goals of the course are: i) to provide an overview of the activities of a clinical laboratory looking at the organizational context and current business; ii) to illustrate the various stages which are at the basis of main analytical methods, either molecular or biochemical, used in biomedical laboratories for modern diagnostic purposes; iii) to provide the key of Interpretation for the obtained results from a pathophysiological point of view. To promote a critical approach towards laboratori diagnosis. - Derived from 20401653 BIOCHIMICA E BIOLOGIA MOLECOLARE CLINICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 BARONI SILVIA (syllabus) • LABORATORY MEDICINE AND CLINICAL BIOCHEMISTRY BIOCHEMICAL TESTS AND LABORATORY MANAGEMENT PREANALYTICAL, ANALYTICAL AND BIOLOGICAL VARIABILITY REFERENCE VALUES • QUALITY CONTROL ASSURANCE • ANALYTICAL METHODS IMMUNOCHEMISTRY AND INTERFERENCES • LABORATORY ANDCARDIOVASCULAR DISEASES LIPIDS AND MARKERS OF CARDIAC DAMAGE • LABORATORY AND DIABETES MELLITUS • LABORATORY AND RENAL FUNCTION URINALYSIS • ACID-BASE BALANCE • LABORATORY AND NEUROLOGICAL DISEASES CEREBROSPINAL FLUID • LABORATORY AND ONCOLOGY • LABORATORY AND THYROID • LABORATORY AND MALE INFERTILITY • INTRODUCING CLINICAL MOLECULAR BIOLOGY (reference books) GIORGIO FEDERICI ET AL. MEDICINA DI LABORATORIO. MC GRAW-HILL. MILANO, 2008	6	BIO/12	48	-	-	-	Related or supplementary learning activities	ITA
20401656 - BIOGEOGRAPHY (objectives) AFTER THE COURSE, THE STUDENTS SHOULD BE ABLE TO: 1) DISCUSS THE HISTORICAL AND ECOLOGICAL FACTORS THAT AFFECTED THE GEOGRAPHICAL DISTRIBUTION OF ANIMALS AND PLANTS; 2) FORMULATE HYPOTHESES AND MODELS EXPLAINING THE SHAPE, SIZE AND POSITION OF THE GEOGRAPHIC RANGE OF A TAXON; 3) DISCUSS EVENTS OF RANGE EXPANSION OR CONTRACTION, DUE TO CLIMATIC CHANGES OR HABITAT TRANSFORMATION CAUSED BY HUMAN ACTIVITIES; 4) DESCRIBE THE FAUNA, FLORA AND VEGETATION OF EACH CONTINENT, IN RELATION TO PAST AND PRESENT GEOGRAPHICAL AND ECOLOGICAL FACTORS; 5) BUILD PREDICTIVE MODELS FOR BIODIVERSITY CONSERVATION AND MANAGEMENT, IN CONNECTION WITH CLIMATE CHANGES AND LANDSCAPE ALTERATION. - CARPANETO GIUSEPPE (syllabus) GENERAL BIOGEOGRAPHY (3 CFU). SCHOOLS AND METHODS FOR STUDYING THE GEOGRAPHICAL DISTRIBUTION OF THE ORGANISMS. RELATIONS AMONG BIOGEOGRAPHY, ECOLOGY, SYSTEMATICS AND EARTH SCIENCES. PALEOGEOGRAPHY AND THE THEORY OF CONTINENTAL DRIFT; PLEISTOCENE CHANGES IN CLIMATE AND COASTLINE SHAPE (GLACIAL/INTERGLACIAL AND PLUVIAL/INTERPLUVIAL PERIODS, MARINE REGRESSIONS AND TRANSGRESSIONS) WITH THEIR EFFECTS ON ANIMAL AND PLANT DISTRIBUTION. THE GEOGRAPHIC RANGE (DISPERSAL, COLONIZATION, BARRIERS, EXTINCTION). ISLAND BIOGEOGRAPHY AND FRAGMENTATION BIOLOGY. ENDEMIC AND RELIC SPECIES. VICARIANCE AND DISPERSAL. SIGNIFICANCE AND BORDERS OF THE BIOGEOGRAPHIC REGIONS, TRANSITIONAL ZONES AND BIOMES. ANALYSIS OF BIOGEOGRAPHICAL REGIONS AND TRANSITIONAL ZONES (3 CFU): OLOARCTIC REGION (PALEARCTIC AND NEARCTIC SUBREGIONS), AFROTROPICAL REGION, INDOMALAYAN REGION, AUSTRALIAN REGION. GEOGRAPHICAL AND ECOLOGICAL TRAITS OF EACH BIOGEOGRAPHICAL REGION AND BASIC KNOWLEDGE ON FAUNA, FLORA AND VEGETATION. EXAMPLES OF SPECIES AND TAXONOMIC GROUPS ENDEMIC TO DIFFERENT BIOMES FOR EACH REGION, WITH HYPOTHESES ON THEIR ORIGIN. STUDY CASES: MADAGASCAR AND NEW ZEALAND. (reference books) ZUNINO M & ZULLINI A, 2004. BIOGEOGRAFIA (SECONDA EDIZIONE). CASA EDITRICE AMBROSIANA, MILANO (MAIN TEXT) + DOCUMENTI ELETTRONICI DISTRIBUITI DAL DOCENTE. FOR A DEEPER INSIGHT: LOMOLINO MV ET AL., 2010. BIOGEOGRAPHY (FOURTH EDITION), SINAUER ASSOCIATES MORRONE JJ, 2009. EVOLUTIONARY BIOGEOGRAPHY: AN INTEGRATIVE APPROACH WITH CASE STUDIES. COLUMBIA UNIVERSITY PRESS. The professor receives every day from 15:00 to 18:30 by appointment via email: giuseppe.carpaneto@uniroma3.it	6	BIO/05	48	-	-	-	Related or supplementary learning activities	ITA
20401660 - CHIMICA ANALITICA
20401665 - MANAGEMENT AND PLANNING OF HISTORICAL GARDENS AND ARCHAEOLOGICAL SITES (objectives) STUDY THE RELATIONSHIP BETWEEN MAN & NATURE IN THE ANCIENT TIME. STUDY BIODETERIORATION RELATED TO THE VEGETATION IN THE ARCHAEOLOGICAL AREAS. ANALYSE HOW WAS THE PLANNING OF ARCHAEOLOGICAL PARKS IN ITALY AND DESCRIBE THE PROBLEMS OF MANAGEMENT. STUDY HISTORICAL PARKS, GIVING EXAMPLES FROM THE ASSYRO-BABYLONIANS, EGYPTIANS, GREEK-ROMANS, MEOIOEVAL TIMES TO MODERN AND CONTEMPORARY AGE. DESCRIBE THE PROBLEMS OF MANAGEMENTS OF HISTORICAL GARDENS. GIVE PRACTICAL FIELD EXAMPLES, VISITING AREAS SUCH AS COLOSSEUM AND HORTI FARNESIANI ON THE PALATINE, ARCHAEOLOGICAL AREAS IN THE APPIA ANTICA, AND OTHER HISTORICAL PARKS IN THE CENTRAL ITALY.
20401668 - ENVIRONMENTAL MICROBIOLOGY (objectives) THE MAIN AIMS OF THE COURSE ARE: 1) RECOGNIZE MAJOR GROUPS OF MICROORGANISMS AND UNDERSTAND FACTORS INFLUENCING THEIR ENVIRONMENTAL DISTRIBUTION AND INTERACTIONS WITH HIGHER ORGANISMS; 2) LEARN ABOUT ROLES PLAYED BY MICROBES IN SOIL FORMATION, MINERAL WEATHERING, CARBON AND NITROGEN CYCLING; 3) LEARN ABOUT CULTURE-BASED AND CULTURE-INDEPENDENT MICROBIOLOGICAL METHODS; 4) GAIN LITERACY IN CRITICAL READING AND ANALYSIS OF SCIENTIFIC LITERATURE IN THE FIELD OF ENVIRONMENTAL MICROBIOLOGY.
20401668-2 - MODULO 2 - CASALINO MARIA ASSUNTA (syllabus) DURING LESSONS, THE FOLLOWING TOPICS WILL BE COVERED - DISTRIBUTION AND ACTIVITY OF MICROORGANISMS IN MARINE, FRESHWATER AND TERRESTRIAL ECOSYSTEMS – EXTREME ENVIRONMENTS -THE ROLE OF BACTERIA IN CYCLING ORGANICS. THE MOST WELL-KNOWN AND IMPORTANT BIOGEOCHEMICAL CYCLES: CARBON, NITROGEN SULFUR AND IRON CYCLES-INTERACTION INVOLVIG MICRORGANISMS: COMPETITION, COMMENSALISM, MUTUALISM, PARASITISM, PREDACTION - SENSING AND ADAPTIVE RESPONSES OF BACTERIA TO CHANGES IN DIFFERENT ENVIRONMENTAL CONDITIONS (CHANGES IN TEMPERATURE, NUTRIENTS, PH, CONCENTRATIONS OF IONS) - COMMUNICATION IN BACTERIA THROUGH THE EXCHANGE OF CHEMICAL SIGNAL MOLECULES: -APPLICATION OF MOLECULAR TECHNOLOGIES CURRENTLY AVAILABLE FOR THE STUDY OF THE COMPOSITION AND DIVERSITY OF MICROBIAL COMMUNITIES (reference books) TEACHING MATERIAL:- SELECTED TOPICS WILL BE AVAILABLE ON BROCK BIOLOGY OF MICROORGANISMS TEXTBOOK BY MADIGAN, MARTINKO AND PARKER - SPECIFIC RESEARCH PAPERS WILL BE PROVIDED DURING THE COURSE	,5	BIO/19	-	-	5	-	Related or supplementary learning activities	ITA
20401668-1 - MODULO 1 - CASALINO MARIA ASSUNTA (syllabus) DURING LESSONS, THE FOLLOWING TOPICS WILL BE COVERED - DISTRIBUTION AND ACTIVITY OF MICROORGANISMS IN MARINE, FRESHWATER AND TERRESTRIAL ECOSYSTEMS – EXTREME ENVIRONMENTS -THE ROLE OF BACTERIA IN CYCLING ORGANICS. THE MOST WELL-KNOWN AND IMPORTANT BIOGEOCHEMICAL CYCLES: CARBON, NITROGEN SULFUR AND IRON CYCLES-INTERACTION INVOLVIG MICRORGANISMS: COMPETITION, COMMENSALISM, MUTUALISM, PARASITISM, PREDACTION - SENSING AND ADAPTIVE RESPONSES OF BACTERIA TO CHANGES IN DIFFERENT ENVIRONMENTAL CONDITIONS (changes in temperature, nutrients, pH, concentrations of ions) - COMMUNICATION IN BACTERIA THROUGH THE EXCHANGE OF CHEMICAL SIGNAL MOLECULES: -APPLICATION OF MOLECULAR TECHNOLOGIES CURRENTLY AVAILABLE FOR THE STUDY OF THE COMPOSITION AND DIVERSITY OF MICROBIAL COMMUNITIES (reference books) TEACHING MATERIAL:- SELECTED TOPICS WILL BE AVAILABLE ON BROCK BIOLOGY OF MICROORGANISMS TEXTBOOK BY MADIGAN, MARTINKO AND PARKER - SPECIFIC RESEARCH PAPERS WILL BE PROVIDED DURING THE COURSE	5,5	BIO/19	44	-	-	-	Related or supplementary learning activities	ITA
20401669 - EXPERIMENTAL MODELS IN BIOLOGY (objectives) THE COURSE PROVIDES BASICS CONCERNING THE EXPERIMENTAL MODELS MOST COMMONLY USED IN BIOLOGICAL RESEARCH.
20401671 - GENERAL PATHOLOGY (objectives) Aims of the course: • To acquire the basic knowledge on the human disease causes and their pathogenic mechanisms. • To interpret the pathogenetic and physiopathogenic mechanisms of the human diseases. • To know the operations turned to the analysis of the pathogenetic and physiopathogenic mechanisms of the human diseases and to interpret their results. - Derived from 20401671 PATOLOGIA GENERALE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 MAINIERO FABRIZIO (syllabus) GENERAL AETIOLOGY. CONCEPTS OF HEALTH, PATHOLOGICAL PROCESS AND DISEASE; AETIOLOGY, PATHOGENESIS, EVOLUTION, DISEASE COURSE, OUTCOME. ENVIRONMENTAL DISEASES. DISEASES CAUSED BY PHYSICAL AND CHEMICAL AGENTS INFECTIOUS DISEASES. DISEASES CAUSED BY BIOLOGICAL AGENTS. BACTERIAL ESOTOXINS AND ENDOTOXINS. NEW MECHANISMS OF INFECTIOUS PATHOLOGY. GENETIC DISEASES. DISEASES CAUSED BY GENETIC MUTATIONS. TRANSMISSIONS OF GENETIC DISEASES. TRANSMISSIONS OF MULTIFACTORIAL DISEASES. MAIN HUMAN DISEASES CAUSED BY KARYOTYPIC ANOMALIES. PATHOLOGY OF THE CELL: MECHANISMS OF CELL DAMAGE AND ADAPTIVE CELL REACTIONS. MOLECULAR MECHANISMS OF CELL DAMAGE. HYPOXIC DAMAGE. OXIDATIVE STRESS: FREE RADICAL ORIGIN, LIPIDIC PEROXIDATION, PROTEIN AND DNA OXIDATION. ADAPTIVE CELL REACTIONS: HYPERTROPHY, HYPERPLASIA, ATROPHY. PHENOTYPIC CHANGES: METAPLASIA, DISPLASIA, ANAPLASIA. CELL DEGENERATION: HYDROPIC DEGENERATION; VACUOLAR DEGENERATION; EXCESSIVE DEPOSIT OF INTRACELLULAR MATERIAL, STEATOSIS. CELL DEATH: CELL NECROSIS AND APOPTOSIS. AGING. INFLAMMATION. BASIC CONCEPTS: ACUTE AND CHRONIC INFLAMMATION; VASCULAR AND TISSUE INVOLVEMENT IN INFLAMMATION. RECEPTORS OF INNATE IMMUNITY AND INFLAMMATION. TRANSCRIPTIONAL PROGRAM IN INFLAMMATION. INFLAMMATORY CELLS. CHEMICAL MEDIATORS OF INFLAMMATION: CELLULAR AND HUMORAL ORIGIN. ACUTE INFLAMMATION: VASCULAR PHENOMENA, EXTRACELLULAR FLUIDS AND OEDEMA, DIFFERENT TYPES OF ACUTE INFLAMMATION. CHRONIC INFLAMMATION: GRANULOMA FORMATION. BODY GRANULOMAS. IMMUNOLOGICAL GRANULOMAS. SYSTEMIC EFFECTS OF INFLAMMATION AND THEIR REGULATION: ACUTE PHASE PROTEINS, RATE OF ERYTHROSEDIMENTATION, LEUKOCYTOSIS. PHYSIOPATHOLOGY OF TERMOREGULATION: FEVER. REGULATION OF INFLAMMATORY PROCESS. REPAIR. PHASES OF TISSUE DAMAGE REPAIR. ANGIOGENESIS AND ANGIOGENETIC FACTORS. FIBROBLAST PROLIFERATION, EXTRACELLULAR MATRIX DEPOSITION AND INVOLVED FACTORS. REMODELLING. WOUND HEALING. HEALING OF FIRST AND SECOND INTENTION. PATHOLOGICAL ASPECTS OF WOUND HEALING: KELOIDS. REGENERATION: MODELS OF TISSUE REGENERATION. STEM CELLS. ONCOLOGY: DEFINITIONS AND CLASSIFICATIONS. DEFINITIONS OF TUMORS AND PRE-CANCEROUS CONDITIONS. MORPHOLOGICAL AND BIOCHEMICAL CHARACTERISTICS OF NEOPLASTIC CELLS. HISTOGENETIC TUMOR CLASSIFICATIONS. CLINCIAL CRITERIA OF TUMOR CLASSIFICATIONS: GRADING AND STAGING. MOLECULAR AND GENETIC BASIS OF CANCER. PHYSIOPATHOLOGY OF CELL PROLIFERATION AND DIFFERENTIATION AND GROWTH FACTORS. PHYSICAL, CHEMICAL, VIRAL AND ORMONAL CANCEROGENESIS. IMMUNITY, INFLAMMATION AND TUMORS. ONCOGENES AND THEIR ACTIVATION. ONCOSUPPRESSOR GENES. GENOMIC INSTABILITY. HEREDITARY TUMORS. NEOPLASTIC PROCESS: INITIATION, PROMOTION AND PROGRESSION. MOLECULAR BASIS OF INVASIVENESS. METASTATIC SPREAD. FAVORING FACTORS FOR METASTATIC GROWTH. PRIMARY METABOLIC DISEASES. BASIC CONCEPTS OF AMINOACID METABOLISM AND PHENYLKETONURIA, GLUCIDIC METABOLISM AND DIABETES, LIPIDIC METABOLISM AND DYSLIPIDEMIAS. GENERAL PATHOPHYSIOLOGY: PATHOPHYSIOLOGY OF METABOLISM (AMINO ACIDS, PURINE AND PIRIMIDINICHE, LIPID AND DYSLIPIDEMIA). GENERAL PHYSIOPATHOLOGY OF HAEMATOPOIEC ORGANS AND HAEMOSTASIS. (reference books) PATOLOGIA GENERALE, G.M. PONTIERI ET AL., VOL I, VOL II, PICCIN, 2010 PATOLOGIA GENERALE-PATOLOGIA D’ORGANO E MOLECOLARE, R. RUBIN ET AL, PICCIN, 2014 PATOLOGIA GENERALE CON ELEMENTI DI FISIOPATOLOGIA. ROBBINS, ED. EDRA 2013 FURTHER READING LE BASI PATOLOGICHE DELLE MALATTIE, ROBBINS, VIII ED., VOL I, ELSEVIER, 2010 (IX EDIZIONE IN USCITA NEL 2015) PATOLOGIA, STEVENS, J. LOWE, III ED., CASA ED. AMBROSIANA, 2010	6	MED/04	48	-	-	-	Related or supplementary learning activities	ITA
20401674 - CARTOGRAPHY AND G.I.S. APPLIED TO ECOLOGY (objectives) TO PROVIDE THE THEORETICAL CONCEPTS AND PRACTICAL TOOLS IN GEOGRAPHY, CARTOGRAPHY, AND STATISTICAL ANALYSIS FOR ECOLOGICAL ADVANCES, THROUGH THE USE OF CASE STUDIES AND PRACTICAL APPLICATIONS.
20401777 - PUBLIC HEALTH (objectives) General objectives At the end of the course the student will be able to design epidemiological studies to address public health problems and to identify activities to prevent chronic and infectious diseases. Specific objectives - to know the major mortality and morbidity indicators - to identify the more appropriate epidemiological study to describe the burden of major diseases in the population and to assess the relation between diseases and possible risk factors associated to them - to interpret epidemiological data - to discuss the importance of the health education and health promotion - to list and discuss problems related to water supply, sanitation and waste management - to argue about necessary controls/monitoring to protect the environment and the community - to design health promotion programmes - Derived from 20401777 IGIENE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 TRAMA ANNALISA	6	MED/42	48	-	-	-	Related or supplementary learning activities	ITA
20401782 - MOLECULAR BIOTECHNOLOGY (objectives) THE AIM OF THE COURSE IS TO PROVIDE METHODOLOGIES AND TECHNOLOGIES KNOWLEDGE OF BASIC AND APPLIED ADVANCED RESEARCH IN MOLECULAR BIOTECHNOLOGIES.
20401782-2 - MODULO 2 - Derived from 20401782 BIOTECNOLOGIE MOLECOLARI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) 1. BASIC TECHNOLOGIES OF GENE ANALYSIS; RESTRICTION ENZYMES; ELECTROPHORETIC ANALYSIS. 2. VECTORS; CLONING. 3. PCR; REAL TIME PCR; PCR APPLICATIONS. 4. GENETIC VARIABILITY APPLIED TO FORENSIC SCIENCE 5. GENE IDENTIFICATION; GENOMIC LIBRERIES AND cDNA LIBRERIES; YEAST TWO HYBRID SYSTEM 6. MUTAGENESIS. 7. RECOMBINANT PROTEIN PRODUCTION AND PURIFICATION. 8. FROM SANGER SEQUENCING TO NEXT-GENERATION SEQUENCING. 9. POST-GENOMICS ANALYSIS; TRANSCRIPTOMIC ANALYSIS; REPORTER GENES. 10. PROTEOMIC ANALYSIS. 11. PRODUCTION AND ANALYSIS OF TRANSGENIC PLANTS. 12. GENETIC MODIFICATION OF ANIMAL CELLS; TRANSGENIC ANIMALS CONSTRUCTION. 13. GENE TRAPPING; GENE TARGETING. 14. ANIMAL CLONING; GENE THERAPY. 15. THE CRISPR-CAS SYSTEM: EMERGING TECHNOLOGY AND APPLICATION AND APPLICATIONS. (reference books) Recommended textbooks:1. ANALISI DEI GENI E GENOMI, REECE, EDISES.2. DNA RICOMBINANTE, J.D.WATSON, A.A. CAUDY, R.M. MYERS E J.A. WITKOWSKI, ZANICHELLI.Lecture slides will be provided.The professor receives every day from 10.00 to 11.00 by appointment via e-mail: manuela.cervelli@uniroma3.it	1	BIO/11	-	10	-	-	Related or supplementary learning activities	ITA
20401782-1 - MODULO 1 - Derived from 20401782 BIOTECNOLOGIE MOLECOLARI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) 1.BASIC TECHNOLOGIES OF GENE ANALYSIS; RESTRICTION ENZYMES; ELECTROPHORETIC ANALYSIS. 2. VECTORS; CLONING. 3. PCR; REAL TIME PCR; PCR APPLICATIONS. 4. GENETIC VARIABILITY APPLIED TO FORENSIC SCIENCE 5. GENE IDENTIFICATION; GENOMIC LIBRERIES AND cDNA LIBRERIES; YEAST TWO HYBRID SYSTEM 6. MUTAGENESIS. 7. RECOMBINANT PROTEIN PRODUCTION AND PURIFICATION. 8. PROTEOMICS 9. GENOME PROJECT SEQUENCING 10. POST-GENOMICS ANALYSIS; TRANSCRIPTOMIC ANALYSIS. 11. REPORTER GENES. 12. GENETIC MODIFICATION OF PLANT. 13. GENETIC MODIFICATION OF ANIMAL CELLS. 14. GENETIC MODIFICATION OF ANIMALS; GENE TRAPPING; GENE TARGETING; ANIMAL CLONING. 15.GENE THERAPY. (reference books) ANALYSIS OF GENES AND GENOMES. RICHARD J. REECE. JOHN WILEY & SONS Ltd. RECOMBINANT DNA, GENES AND GENOMES – A SHORT COURSE. J.D.WATSON, A.A. CAUDY, R.M. MYERS E J.A. WITKOWSKIW.H. FREEMAN AND COMPANY	5	BIO/11	40	-	-	-	Related or supplementary learning activities	ITA
20401786 - GENERAL ENTOMOLOGY (objectives) THE MAIN FORMATIVE TARGETS ARE: 1) THE ACQUISITION OF A BASIC KNOWLEDGE ON MORPHOLOGY, ANATOMY, PHYSIOLOGY AND EVOLUTION OF THE MAIN INSECT GROUPS. 2) THE ACQUISITION OF BOTH THEORETICAL AND PRACTICAL KNOWLEDGE ON SYSTEMATICS AND CLASSIFICATION OF THE HEXAPODA. 3) THE CONSTRUCTION OF A SOLID CULTURAL BACKGROUND FOR AN ADVANCED DISCUSSION ON CAUSES AND EFFECTS OF THE AMAZING EVOLUTIONARY SUCCESS AND DIVERSITY OF INSECTS AND ON THEIR IMPORTANCE IN BASIC AND APPLIED STUDIES. 4) THE ACQUISITION OF THE TOOLS FOR THE INSECT TAXONOMIC IDENTIFICATION, EXPECIALLY FOR THOSE ORDERS AND FAMILIES PRESENT IN THE ITALIAN FAUNA. 5) TO STIMULATE THE CURIOSITY AND THE ABILITY OF CRITICALLY OBSERVE THE NATURE. 6) THE SELF-EVALUATION BY THE STUDENT OF THE COMPETENCE WHITIN THE ANIMAL BIOLOGY, AND IN PARTICULAR IN THE ENTOMOLOGY.
20401786-2 - MODULO 2 - DI GIULIO ANDREA (syllabus) Classification: diagnostic characters at the level of orders and outline of the most important families, with particular regard to the Italian fauna and the aspects of biology and ecology. Phylogeny of insects.Esapodi Apterigoti: COLLEMBOLA, PROTURA, DIPLURA, MICROCORYPHIA, ZYGENTOMA. Paleotteri: EPHEMEROPTERA, ODONATA. Polineotteri (orthopteroid orders): PLECOPTERA, EMBIOPTERA, DICTYOPTERA, ISOPTERA, GRYLLOBLATTODEA, DERMAPTERA, PHASMIDA, ORTOPTERA, ZORAPTERA, MANTOFASMATODEA. Paraneoptera (emitteroid orders): PSOCOPTERA, PHTHIRAPTERA, THYSANOPTERA, HETEROPTERA. Homoptera. Oligoneotteri: MECOPTERA, TRICHOPTERA, LEPIDOPTERA, DIPTERA, SIPHONAPTERA, MEGALOPTERA, RAPHIDIOPTERA, PLANIPENNIA, COLEOPTERA, STREPSIPTERA, HYMENOPTERA. (reference books) P.J. Gullan & P.S. Cranston “Lineamenti di Entomologia” Zanichelli R.G. Davies “Lineamenti di Entomologia” Zanichelli G. Grimaldi “Evolution of the Insects”R.F. Chapman “The Insects: structure and function” Hodder & Stoughton, London C. Gillot “Entomology” Plenum Press, New York O.W. Richards & R.G. Davies “Imm’s general textbook of entomology” Chapman & Hall, London Vol. I e II M. Chinery “Guida agli insetti d’Europa” Muzzio Office Hours: every day of the week by appointment by email (andrea.digiulio@uniroma3.it)	2	BIO/05	-	20	-	-	Related or supplementary learning activities	ITA
20401786-1 - MODULO 1 - DI GIULIO ANDREA (syllabus) 1) Introduction: aim of the course; entomology in the history of Zoology and more generally in the history of science; role of entomology in modern biological disciplines; basic and applied entomology; relationships of insects with man and the environment.2) Generalities on Arthropods; phylogenesis problems of Arthropods; insects in the evolution of terrestrial Arthropods; general information on the Atelocerata, and in particular on the Hexapods; outline of paleontology of insects; insect origin; significance of the evolutionary success of insects.3) Insects as land animals; exoskeleton; structure of the integument and cuticle; chemical and physical colors. External anatomy: regions of the body; sclerites; primary and secondary segmentation; appendices and wings.4) Movement: musculature and endoskeleton; the race; the jump; origin and mechanics of flight; adaptations to aquatic life and importance of surface forces, swimming; the excavation; raptorial and phoretic limbs.5) Breathing; breathing in the aquatic environment; water reabsorption; excretion; adaptations to temperature changes.6) Nutrition: cephalic appendages and mouthparts; anatomy and physiology of the digestive system; food strategies.7) Circulatory system.8) Reproduction: structure and functional morphology of the segments and genital appendages; reproductive systems and reproductive behaviors; parthenogenesis; pedogenesis; polyembryony; meaning of heterogony; eggs; sperm.9) Embryonic and postembryonic development: growth and metamorphosis; types of larvae and types of metamorphosis; diapause; physiology; endocrine glands.10) Communication in insects. Nervous system: components and functioning. Endocrine system: hormones and endocrine organs. Exocrine glands. Perception of the environment. Compound eyes. Vision. Ocelli. Mechanoreceptors. Coloration. Light production. Mechanical communication: production of sound and vibrations of the substrate. Chemical communication: pheromones and secretions of interspecific significance.11) Intraspecific relationships; parental care; society; interspecific relationships; predation; parasitism.12) Orientation; migrations; dispersion.13) Aspects of applied entomology: medical entomology, agricultural entomology, entomology in environmental assessment, insect conservation, urban entomology, veterinary entomology, entomology applied to conservation of cultural heritage. (reference books) P.J. Gullan & P.S. Cranston “Lineamenti di Entomologia” Zanichelli R.G. Davies “Lineamenti di Entomologia” Zanichelli G. Grimaldi “Evolution of the Insects”R.F. Chapman “The Insects: structure and function” Hodder & Stoughton, London C. Gillot “Entomology” Plenum Press, New York O.W. Richards & R.G. Davies “Imm’s general textbook of entomology” Chapman & Hall, London Vol. I e II M. Chinery “Guida agli insetti d’Europa” Muzzio Office Hours: every day of the week by appointment by email (andrea.digiulio@uniroma3.it)	4	BIO/05	32	-	-	-	Related or supplementary learning activities	ITA
20401787 - ETHNOBOTANY AND ETHNOZOOLOGY (objectives) ANALYSIS OF ECOLOGICAL AND CULTURAL RELATIONS BETWEEN HUMANS AND LIVING BEINGS, THROUGH AN HISTORICAL AND GEOGRAPHIC SURVEY AT DIFFERENT LEVELS OF CIVILIZATION. PERSPECTIVES OF THE RECOVERY OF POPULAR TRADITIONS.
20401788 - STRATEGIC ENVIRONMENTAL ASSESSMENT (objectives) To provide the basics in terms of technical, legal, scientific and cultural issues on environmental assessment tools, with particular reference to the Environmental Impact Assessment, the Strategic Environmental Assessment, the assessment of impacts, the indicators for the monitoring and reporting of environmental . The knowledge acquired by the students, integrated with the content of other courses within the degree course (Technical Cartographic and GIS, Statistics, Applied Ecology, Management of Ecosystems, Biodiversity, etc..) contributes to develop professional figures in environmental monitoring.
20401821 - IMMUNOLOGY (objectives) to deeply understand cellular and molecular mechanisms of immune response and their role in health and disease. - Derived from 20401821 IMMUNOLOGIA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 DI ROSA FRANCESCA (syllabus) LYMPHOID ORGANS: BONE MARROW, THYMUS, LYMPH NODES AND LYMPHATIC SYSTEM, SPLEEN, MUCOSE ASSOCIATED LYMPHOID SYSTEM. B LYMPHOCYTE DEVELOPMENT: SELECTION AND MATURATION OF B CELLS. IMMUNOGLOBULIN STRUCTURE AND IMMUNOGLOBULIN GENE REARRANGEMENT. T LYMPHOCYTE DEVELOPMENT: SELECTION AND MATURATION OF T CELLS. TCR STRUCTURE AND TCR GENE REARRANGEMENT. ANTIGEN PRESENTING CELLS AND INNATE IMMUNITY RECEPTORS. MHC: GENES AND PROTEINS. ANTIGEN PROCESSING. INDUCTION OF PRIMARY RESPONSE: DENDRITIC CELL ACTIVATION, INDUCTION OF ANTIGEN-SPECIFIC RESPONSE OF T AND B LYMPHOCYTES. CYTOKINES: GENERAL CHARACTERISTICS CYTOKINES REGULATING INNATE IMMUNITY, CYTOKINES REGULATING ANTIGEN-SPECIFIC IMMUNITY. IL-1 SUPERFAMILY, INFLAMMOSOME; TNF SUPERFAMILY. CHEMOKINES: GENERAL CHARACTERISTICS, INFLAMMATORY AND HOMEOSTATIC CHEMOKINES. IMMUNITY AGAINST INFECTIONS. IMMUNOLOGICAL MEMORY AND VACCINES. TOLERANCE AND AUTOIMMUNITY: CENTRAL AND PERIPHERAL TOLERANCE, BREKING OF TOLERANCE, AUTOIMMUNITY AND DISEASES. ALLERGIES: CAUSES AND TYPES OF HYPERSENSIBILITY DISEASES. PRIMARY AND SECONDARY IMMUNODEFICIENCIES: GENERAL CHARACTERISTICS, CLASSIFICATION, GENE THERAPY EXAMPLES. MAIN CONCEPTS ON ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS). TUMORS AND IMMUNITY: TUMORAL ANTIGENS, IMMUNE RESPONSE TO TUMORS, IMMUNOTHERAPY AND VACCINATION AGAINST TUMORS. TRANSPLANTATION: ANTI-GRAFT IMMUNE RESPONSE, EFFECTOR MECHANISMS, BIOTECHNOLOGICAL TOOLS FOR INTERVENTION. (reference books) K. MURPHY. , IMMUNOBIOLOGIA DI JANEWAY , 8° EDIZIONE, PICCIN, 2012. A.K. ABBAS, A. H. LICHTMAN, S. PILLAI , IMMUNOLOGIA CELLULARE E MOLECOLARE , 7° EDIZIONE, ELSEVIER MASSON, 2012. TAK. W. MAK, M. SAUNDERS, FONDAMENTI DI IMMUNOLOGIA, ZANICHELLI, 2012	6	MED/04	48	-	-	-	Related or supplementary learning activities	ITA
20401875 - METHODS AND TECHNIQUES OF EDUCATION AND PROMOTION OF NATURALISTIC AND ENVIRONMENTAL ISSUES (objectives) Students’ grow in knowledge, skills and abilities in order to become a professional in the fields of education and naturalistic and environmental dissemination. Making students aware of the professions related to dissemination and education in the field of nature and environment as potential job opportunities for specialists of management and protection of ecosystems.
20401990 - CELLULAR BIOCHEMISTRY (objectives) The aim of the course is to introduce students to the “inorganic biofactors”, starting from their biochemical role to the analysis of their impact on human health. In the second part of the course we will focus on the “omics”, which represents a broad discipline of science (from trascriptomics to metabolomics) intended for analyzing system biology and for characterizing the biochemical events associated to transcripts, proteins and metabolites variations in fluids, organs and tissues. - Derived from 20401990 BIOCHIMICA CELLULARE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 DI MASI ALESSANDRA, POLTICELLI FABIO (syllabus) HEME-PROTEINS. HEME METABOLISM AND RELATED DISEASES. HEME BIOSYNTHESIS AND RELATED DISEASES. IRON METABOLISM AND RELATED DISEASES. INORGANIC BIOFACTORS: OXYGEN, CARBON MONOXIDE, NITROGEN MONOXIDE, HYDROGEN SULFIDE. BIOCHEMICAL AND CELLULAR ROLES OF THE INORGANIC BIOFACTORS. ROLE IOF THE INORGANIC BIOFACTORS IN HUMANN DISEASES ONSET. THE THERAPEUTIC USE OF THE INORGANIC BIOFACTORS. REACTIVE OXYGEN AND NITROGEN SPECIES. MITOCHONDRIAL DISEASES. THE ENERGETIC MATTER OF CANCER CELLS. THE METABOLIC REQUIREMENTS OF CANCER CELLS: THE WARBURG EFFECT. (reference books) SCIENTIFIC PAPERS SUPPLIED BY THE TEACHER. Support texts: Siliprandi & Tettamanti "Biochimica Medica - strutturale, metabolica e funzionale" Ed. Piccin - Chiurchiù & Maccarrone "I radicali liberi e la loro rilevanza in biomedicina: dai meccanismi molecolari alle prospettive terapeutiche" Ed Piccin RECEPTION TIME: Monday 10 am	6	BIO/10	48	-	-	-	Related or supplementary learning activities	ITA
20401992 - MICROBIAL BIOTECHNOLOGY LABORATORY (objectives) THE MAIN AIMS OF THE COURSE ARE: A) ACQUISITION OF APPROPRIATE METODOLOGIES AND LANGUAGES FOR THE ISOLATION, OBSERVATION AND DESCRIPTION OF INDUSTRIAL MICROORGANISMS B) ACQUISITION OF THE BASIC KNOWLEDGE FOR THE DRAFTING AND EXECUTION OF AN EXPERIMENTAL PROTOCOL
20401992-2 - MODULO 2 - Derived from 20401992 LABORATORIO DI BIOTECNOLOGIE DEI MICRORGANISMI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) DURING THE LABORATORY PRACTICES AND THE CORRESPONDING THEORETIC LESSONS, THE FOLLOWING TOPICS WILL BE COVERED:- ISOLATION OF MICROORGANISMS OF INDUSTRIAL RELEVANCE FROM THE ENVIRONMENT, PREPARATION OF GROWTH MEDIA AND CULTIVATION TECHNIQUES- SELECTION AND SCREENING OF GENETIC MUTANTS- GENETIC TRANSFER PROCESSES (CONJUGATION AND TRANSFORMATION)THE FOLLOWING TOPICS WILL BE COVERED IN ADDITIONAL THEORETIC LESSONS: - DEVELOPMENT OF INNOVATIVE THERAPEUTIC STRATEGIES BASED ON BIOTECHNOLOGICAL PROCESSES- DEVELOPMENT OF BIOSENSORS AND REPORTER SYSTEMS FOR THE IDENTIFICATION OF NEW DRUGS- APPLICATION OF SYNTHETIC BIOLOGY TO MICROBIAL BIOTECHNOLOGY- PROPERTIES OF THE REGULATORY NETWORKS AND THEIR APPLICATION TO BIOTECHNOLOGICAL PROCESSES (reference books) TEACHING MATERIAL:- SELECTED TOPICS WILL BE AVAILABLE ON SUGGESTED MICROBIOLOGY AND MICROBIAL BIOTECHNOLOGY BOOKS- SPECIFIC RESEARCH PAPERS AND EXPERIMETAL PROTOCOLS WILL BE PROVIDED DURING THE LABORATORY PRACTICES AND THE THEORETIC LESSONS	3	CHIM/11	-	30	-	-	Related or supplementary learning activities	ITA
20401992-1 - MODULO 1 - Derived from 20401992 LABORATORIO DI BIOTECNOLOGIE DEI MICRORGANISMI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) Programma (ENG)The course aims at providing to the student:- adequate knowledge and understanding on advanced methodologies in microbial biotechnology, appropriate methodologies and communication skills for the isolation, observation, description and engineering of industrial microorganisms;- adequate applied knowledge for drafting and executing experimental protocols, and for retrieving and critically reviewing relevant scientific literature from on-line databases (making judgements).ProgrammeDuring the laboratory practices and the corresponding theoretic lessons, the following topics will be covered:- isolation of microorganisms of industrial relevance from the environment, preparation of growth media and cultivation techniques;- transposon–based mutagenesis (generation and screening of mutant libraries);- genetic transfer processes (conjugation and transformation);- use of whole-cell bacterial biosensors for gauging specific molecules produced by other microorganisms.The following topics will be covered in additional theoretic lessons: - development of innovative therapeutic strategies based on biotechnological processes;- development of biosensors and reporter systems for the identification of new drugs;- application of synthetic biology to microbial biotechnology;- properties of the regulatory networks and their application to biotechnological processes. (reference books) Selected topics will be available on suggested Microbiology and Microbial Biotechnology books, as indicated in the following reference list. Specific research papers and experimental protocols will be provided during theoretic lessons on advanced research topics and laboratory practices. Innovative teaching will be promoted by cloud-sharing of power-point presentations illustrating the main topics of the course. Moreover, students will be encouraged to make use of web-based resources and databases to autonomously increase their knowledge on specific advanced topics. Students can be received at the best of their convenience if an appointment has been fixed at the end of the lessons or by email.	3	CHIM/11	24	-	-	-	Related or supplementary learning activities	ITA
20402204 - BIO-ORGANIC CHEMISTRY (objectives) The course will address the chemical transformations shared by organic chemistry and biological systems. Indeed, although the functional group elaborations are formally the same, the followed reaction pathways result to be quite different with respect to the experimental conditions of both organic syntheses and biological processes. In such a context, the enzymatic action modes in living systems will be compared with the key role performed by temperature, pressure, pH, catalysts and solvents. Keeping this in mind, a few of the most well-known chemical reaction mechanisms will be studied, underlining, step by step, the main similarities and distinctions with the analogous biological transformations - Derived from 20402204 CHIMICA BIOORGANICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 GASPERI TECLA (syllabus) Cultural skills: the course aims to provide students with the chemical basis of the structure, the properties, and the reactivity of biological molecules, as well as the main notions for understanding the logic that regulates bio-organic chemistry processes. Methodological skills: at the end of the course, the student will be able to analyze and discuss the catalytic mechanism of the most important classes of enzymes, as well as to understand the importance of the organic chemistry applied to the study of biological systems, to biocatalysis, and to the development of biologically active molecules. Introduction to Bio-organic Chemistry (A short overview about the most common functional groups involved in biological processes, highlighting their main features). Organic chemistry mechanisms to explain key steps in pivotal biological pathways: • Electrophilic Addition Reactions:  regioselective epoxidation of alkenes; the action of squalene epoxidase in squalene/lanosterol transformation. • Nucleophilic Substitution Reactions  bimolecular Nucleophilic Substitution Reaction (SN2): the S-adenosylmethionine (SAM) role in the methyltransferase-catalyzed reactions;  carbocation chemistry in the nucleophilic substitution reaction (SN1): the IPP isomerase. • Elimination reactions:  β-elimination reaction and the enolase role in the synthesis of the phosphoenol pyruvate (PEP). • Nucleophilic Carbonyl Addition Reactions  imine and enamine formation; how Schiff bases act in the PLP-dependent enzymatic catalysis;  acetals and sucrose synthase;  Michael additions and the histidine ammonia-lyase function. • Isomerization and epimerization:  keto-enol tautomerism and ribose-5-phosphate isomerase catalysis;  Inversion and retention of the stereochemical configuration: the glucosidase mechanism. • Carbonyl condensation reactions:  aldol condensation promoted by aldolases (classes I and II)  Claisen condensation and the acetyl synthase function in the fatty acids synthesis. • Acyl Nucleophilic Substitutions:  the hydrolysis of esters and the mechanism of Human Pancreatic Lipase;  esterification reactions and the synthesis of triacylglycerols by means of acyl-CoA synthetase and acyltransferase;  amide bond formation; asparagine synthetase vs glutamine synthetase;  the hydrolysis of amides and the chymotrypsin action mode. • Oxidations and reductions  metal hydride and the reduction of the ketone carbonyl group in acetoacetyl ACP due to the β-keto thioester reductase;  Baeyer-Villinger oxidation and the hydroxyacetophenone monooxygenase;  ozonolysis reactions and the dioxygenase enzyme activity. • Carboxylation reactions:  Grignard reactions in CO2 atmosphere; mechanisms of both the pyruvate carboxylase and Ribulose-1,5-bisphosphate carboxylase oxygenase (RuBiscO);  the decarboxylation reaction in both malonic and acetoacetic synthesis; the key role of thiamine pyrophosphate (TPP) in the 1-deoxy-D-xylulose 5-phosphate synthase catalysis. • Noteworthy examples: pyruvate dehydrogenase complex, the kynurenine catalysis and the tryptophan metabolism; anomalous features in in histidine metabolism. (reference books) Textbook: John McMurry, Tadhg Begley in “Chimica Bio-Organica”, Zanichelli Ed. spa Others: T.W. Graham Solomons; Craig B. Fryhle in “Organic Chemistry”, 10th Edition, Wiley. John McMurry in “Chimica Organica”, Piccin-Nuova Libreria Papers from the current literature Notes from the teacher The teacher receives Tuesday from 17.00 to 19.00 by appointment via e-mail: tecla.gasperi@uniroma3.it	6	CHIM/06	48	-	-	-	Related or supplementary learning activities	ITA
22402256 - EVOLUTIONARY PARASITOLOGY (objectives) Offering the students a new perspective in the study of parasitology, by means of an ecological- evolutionary and comparative approach. The intimate and intricate nature of the association between host and parasite, has traditionally been studied by giving emphasis on its pathogeniticy for non human animal and human hosts. In contrast, this course offers the student the opportunity to deepen topics such as adaptive strategies of parasitic life-style, the impact of parasitism on the community structure or else the role of a parasite in the trophic energy transfer in the community. Emphasis will be given to the host as key element in the parasite environment and, as such, its important role as a selective pressure. The student will be provided with a dynamic course made of lectures, workshops and tutorials on taxa parasites
22402256-1 - MODULO 1 - MANCINI EMILIANO	5	BIO/05	40	-	-	-	Related or supplementary learning activities	ITA
22402256-2 - MODULO 2 - MANCINI EMILIANO	1	BIO/05	-	10	-	-	Related or supplementary learning activities	ITA
22402257 - GENERAL AND APPLIED ANIMAL VIROLOGY (objectives) OBJECTIVS: TO ACQUIRE A SOLID FOUNDATION IN ANIMAL VIROLOGY AND THEIR APPLICATION.
22402257-1 - MODULO 1 - Derived from 22402257 VIROLOGIA ANIMALE GENERALE ED APPLICATA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) THE COURSE DESCRIBES AND COMPARES THE REPLICATION CYCLES OF DIFFERENT ANIMAL VIRUSES THAT INFECT VERTEBRATE HOSTS TO GAIN INSIGHT INTO: ORIGIN OF VIRUSES, STRUCTURE, EVOLUTION, VIRUS-CELL INTERACTIONS, HOST DEFENSE MECHANISMS AND STRATEGIES OF VIRAL IMMUNOEVASIONS, METHODS OF DETECTION, IDENTIFICATION AND TITRATION, ANTIVIRAL DRUGS AND PROFILAXIS OF VIRAL INFECTIONS. IN PARTICULAR, IT WILL BE DESCRIBED VIRUSES OF THE FOLLOWING VIRAL FAMILIES: PICORNAVIRIDAE, ORTOMIXOVIRIDAE, PARAMIXOVIRIDAE, RABDOVIRIDAE, RETROVIRIDAE, HEPADNAVIRIDAE, FLAVIVIRIDAE, PARVOVIRIDAE, POLIOMAVIRIDAE, PAPILLOMAVIRIDAE, ADENOVIRIDAE, HERPESVIRIDAE, POXVIRIDAE. IN ADDITION INTRODUCTION TO APPLIED VIROLOGY WILL BE PROVIDED (i.e., VACCIN DEVELOPMENT, VIRAL VECTORS AND ONCOLYTIC VIRUSES) (reference books) WHERE TO STUDY:-EDWARD K.WAGNER E MARTINEZ J.HEWLETT - BASIC VIROLOGY - BLACKWELL SCIENCE - THIRD EDITION –-FLINT S.J., ENQUIST L.W., KRUG R.M., RACANIELLO V.R., SKALKA A.M. - PRICIPLES OF VIROLOGY - ASM (AMERICAN SOCIETY FOR MICROBIOLOGY) PRESS - ADENOVIRAL, ADENO-ASSOCIATED, RETROVIRAL AND LENTIVIRAL VECTORS + ONCOLITIC ADENOVIRUSES:FIELDS VIROLOGY, VTH EDITION, 2007- D.M.KNIPE AND P.M.HOWLEY EDITORS-IN-CHIEF -LIPPINCOT WILLIAMS & WILKINS PUBLISHERS, CAP.16 VIRAL VECTORS AND THEIR APPLICATIONS - It is available a CD with supplementary material at the box office of segreteria didattica biologia INTERNET ADDRESS:HTTP://MICROBIOLOGYBYTES.COM (CLICK ON SITEMAP): strongly recommendedHTTP://WWW.VIROLOGY.WS/HTTP://WWW.ASM.ORG, HTTP://WWW.ASV.ORG, HTTP://WWW.CDC.ORGHTTP://WWW.VIROLOGY.NETIN DEPTH BOOKS AVAILABLE AT THE LIBRARY OF SCIENCE & TECHNOLOGY:- Fields Virology, Vth edition, 2007-D.M.Knipe, P.M.Howley, D.E.Griffin, R.A. Lamb and M.A.Martin editors-Lippincot Williams & Wilkins Publishers-Topley & Wilson's Microbiology and microbial infections, 2010 - Wiley-Interscience –VOL.VIROLOGY:	5	BIO/19	40	-	-	-	Related or supplementary learning activities	ITA
22402257-2 - MODULO 2 - Derived from 22402257 VIROLOGIA ANIMALE GENERALE ED APPLICATA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) THE COURSE DESCRIBES AND COMPARES THE REPLICATION CYCLES OF DIFFERENT ANIMAL VIRUSES THAT INFECT VERTEBRATE HOSTS TO GAIN INSIGHT INTO: ORIGIN OF VIRUSES, STRUCTURE, EVOLUTION, VIRUS-CELL INTERACTIONS, HOST DEFENSE MECHANISMS AND STRATEGIES OF VIRAL IMMUNOEVASIONS, METHODS OF DETECTION, IDENTIFICATION AND TITRATION, ANTIVIRAL DRUGS AND PROFILAXIS OF VIRAL INFECTIONS. IN PARTICULAR, IT WILL BE DESCRIBED VIRUSES OF THE FOLLOWING VIRAL FAMILIES: PICORNAVIRIDAE, ORTOMIXOVIRIDAE, PARAMIXOVIRIDAE, RABDOVIRIDAE, RETROVIRIDAE, HEPADNAVIRIDAE, FLAVIVIRIDAE, PARVOVIRIDAE, POLIOMAVIRIDAE, PAPILLOMAVIRIDAE, ADENOVIRIDAE, HERPESVIRIDAE, POXVIRIDAE. IN ADDITION INTRODUCTION TO APPLIED VIROLOGY WILL BE PROVIDED (i.e., VACCIN DEVELOPMENT, VIRAL VECTORS AND ONCOLYTIC VIRUSES) (reference books) WHERE TO STUDY:-EDWARD K.WAGNER E MARTINEZ J.HEWLETT - BASIC VIROLOGY - BLACKWELL SCIENCE - THIRD EDITION –-FLINT S.J., ENQUIST L.W., KRUG R.M., RACANIELLO V.R., SKALKA A.M. - PRICIPLES OF VIROLOGY - ASM (AMERICAN SOCIETY FOR MICROBIOLOGY) PRESS - ADENOVIRAL, ADENO-ASSOCIATED, RETROVIRAL AND LENTIVIRAL VECTORS + ONCOLITIC ADENOVIRUSES:FIELDS VIROLOGY, VTH EDITION, 2007- D.M.KNIPE AND P.M.HOWLEY EDITORS-IN-CHIEF -LIPPINCOT WILLIAMS & WILKINS PUBLISHERS, CAP.16 VIRAL VECTORS AND THEIR APPLICATIONS - It is available a CD with supplementary material at the box office of segreteria didattica biologia INTERNET ADDRESS:HTTP://MICROBIOLOGYBYTES.COM (CLICK ON SITEMAP): strongly recommendedHTTP://WWW.VIROLOGY.WS/HTTP://WWW.ASM.ORG, HTTP://WWW.ASV.ORG, HTTP://WWW.CDC.ORGHTTP://WWW.VIROLOGY.NETIN DEPTH BOOKS AVAILABLE AT THE LIBRARY OF SCIENCE & TECHNOLOGY:- Fields Virology, Vth edition, 2007-D.M.Knipe, P.M.Howley, D.E.Griffin, R.A. Lamb and M.A.Martin editors-Lippincot Williams & Wilkins Publishers-Topley & Wilson's Microbiology and microbial infections, 2010 - Wiley-Interscience –VOL.VIROLOGY:	1	BIO/19	-	10	-	-	Related or supplementary learning activities	ITA
20402024 - BIOCHEMICAL PHYSICS (objectives) THE COURSE AIMS TO PROVIDE THE STUDENT WITH BASIC KNOWLEDGE ON THERMODYNAMICS AND KINETICS OF BIOLOGICAL PROCESSES, PARTICULARLY IN RELATIONSHIP WITH THE EXPERIMENTAL ACTIVITY IN THE LABORATORY. - Derived from 20402024 BIOCHIMICA FISICA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 ANTONINI GIOVANNI (syllabus) Cultural competences (Knowledge of :) The Course aims to provide students with basic knowledge relating to thermodynamics and the kinetics of biological processes, particularly in relation to experimental activities in the laboratory. Methodological skills (Know How to:) acquire and use experimental data relating to: to the study of interactions between proteins and ligands, enzyme kinetics and kinetic of binding Program: 1) Study of the interaction between receptors and ligands: methods at equilibrium and transient kinetics: a) At equilibrium (thermodynamic parameters: Kd: dissociation constant at equilibrium, cooperativity, number of binding sites) b) Rapid kinetics (kinetic parameters: k: velocity constants) 2) Study of enzymatic activity: steady state kinetics a) In Steady State (when [ES] is almost constant during experimental observation) b) In the presence of inhibitors 3) Time-resolved optical spectroscopy and complex kinetics (reference books) Recommended textbooks: M. C. Bonaccorsi di Patti et al. Metodologie Biochimiche - Casa Editrice Ambrosiana Ninfa/Ballou Metodologie di base per la Biochimica e la Biotecnologia - ed. Zanichelli Reed et al. Metodologie di Base per le Scienze Biomolecolari- ed. Zanichelli P. Silvestroni, Fondamenti di chimica - Casa Editrice Ambrosiana D.M. Etter Introduction to MATLAB 7– Pearson Education, Inc. Software to use EXCEL (Office) or CALC (Open Office) * (for linear methods) MATLAB (Mathworks) or OCTAVE (GNU Octave) * (for spectral analysis and non-linear methods) GEPASI (P. Mendes et al.) * Or COPASI (Copasi dev. Group) * (for complex reactions) (*) indicates free software Lecture notes and calculation exercises will be provided The professor receives every day from	6	BIO/11	48	-	-	-	Related or supplementary learning activities	ITA
20402025 - Bioindication and Environmental Monitoring (objectives) Acquisition of specific knowledge on bioindication and its applications, particularly with regard to plant and animal organisms used as biological indicators of the environmental status. Knowledge of the experimental methods and data processing for the environmental monitoring.
20402025-1 - MODULO 1 - CESCHIN SIMONA (syllabus) Bioindication: basic concepts. Main ecological characteristics of a bioindicator. Two ways of bioindicate: react and accumulate. The homeostasis of the bioindicators. Times and ecological relevance of the bioindicator responses to environmental changes. Meaning of stress and stressor.Bioindication at different levels of biological organization. Integrity and functionality of the ecosystem. Check of the plant and animal communities status and evaluation of the environmental quality. Two types of ecosystem approach: the theories of the Top-down and Buttom-Up.Bioindication and environmental monitoring. Bioindication in aquatic, terrestrial and aerial environmental. Main examples of application of the bioindication procedures. Assessment of the environmental quality through ecological and biotic indices. Experimental and standard techniques for the biomonitoring. The Bioindication in Italy. Main European and national directives. National and international institutional bodies for the environmental monitoring. (reference books) Pdfs of the lessons performed during the course and the book: Bioindicatori ambientali, 1998, edited by F. Sartori, Graphic Arts Juri Iodice, Sannazzaro (PV).The teacher receives Mon, Wed, Fri from 9.00 to 10.00 by appointment via email: simona.ceschin@uniroma3.it	5,5	BIO/02	44	-	-	-	Related or supplementary learning activities	ITA
20402025-2 - MODULO 2 - CESCHIN SIMONA (syllabus) Bioindication: basic concepts. Main ecological characteristics of a bioindicator. Two ways of bioindicate: react and accumulate. The homeostasis of the bioindicators. Times and ecological relevance of the bioindicator responses to environmental changes. Meaning of stress and stressor.Bioindication at different levels of biological organization. Integrity and functionality of the ecosystem. Check of the plant and animal communities status and evaluation of the environmental quality. Two types of ecosystem approach: the theories of the Top-down and Buttom-Up.Bioindication and environmental monitoring. Bioindication in aquatic, terrestrial and aerial environmental. Main examples of application of the bioindication procedures. Assessment of the environmental quality through ecological and biotic indices. Experimental and standard techniques for the biomonitoring. The Bioindication in Italy. Main European and national directives. National and international institutional bodies for the environmental monitoring. (reference books) Pdfs of the lessons performed during the course and the book: Bioindicatori ambientali, 1998, edited by F. Sartori, Graphic Arts Juri Iodice, Sannazzaro (PV).The teacher receives Mon, Wed, Fri from 9.00 to 10.00 by appointment via email: simona.ceschin@uniroma3.it	,5	BIO/02	-	5	-	-	Related or supplementary learning activities	ITA
20402506 - MOLECULAR BASIS OF PLANT-ENVIRONMENT INTERACTION (objectives) TO INCREASE KNOWLEDGE CONCERNING FUNDAMENTAL PROCESSES UNDERLYING PLANT ACCLIMATION TO DIFFERENT ENVIRONMENTAL STRESSES, USEFUL IN DEVELOPING NEW STRATEGIES FOR IMPROVING CROP PRODUCTIVITY UNDER CHANGING ENVIRONMENTAL CONDITIONS IN THE CONTEXT OF SUSTAINABLE AGRICULTURE. BASIC KNOWLEDGE WILL BE PROVIDED ON PLANT EMPLOYMENT IN PHARMACOLOGICAL, NUTRACEUTICAL AND ENVIRONMENTAL FIELD.
20402507 - Diversity and Ecology of the Soil Fauna
20402508 - NATURAL PRODUCTS AND ENVIRONMENTAL CHEMISTRY (objectives) THE COURSE AIMS AT GIVING: 1) A GENERAL KNOWLEDGE OF THE BIOSYNTHETIC PATHWAYS OF SECONDARY METABOLISM; 2) INFORMATION ABOUT THE MAIN NATURAL PRODUCTS DERIVED FROM MICROORGANISM, PLANTS AND ANIMALS AND THEIR ROLE IN NATURAL ENVIRONMENT; 3) KNOWLEDGE ON THE STRUCTURE/BIOLOGICAL ACTIVITY RELATIONSHIP OF THE MAIN SECONDARY METABOLITES USED IN PHARMACEUTICAL AND HEALTHCARE INDUSTRY. 4) ATTAINMENT OF THE BASIC EDUCATIONAL BACKGROUND NECESSARY TO UNDERSTAND THE CHEMICAL EQUILIBRIA THAT REGULATE THE ORIGINS, THE TRANSPORT, THE TRANSFORMATIONS AND THE EFFECTS OF THE ENVIRONMENTAL CHEMICAL SPECIES, EITHER OF NATURAL OR HUMAN ORIGIN. - TOFANI DANIELA (syllabus) INTRODUCTION TO NATURAL PRODUCTS CHEMISTRY. MAIN FEATURES OF SECONDARY METABOLISM. ACETATE PATHWAY. PROSTAGLANDINS, AROMATIC POLYKETIDES, ANTHRAQUINONES, CANNABINOIDS, AFLATOXINS. SHIKIMATE PATHWAY. SHIKIMIC ACID BIOSYNTHESIS. CINNAMIC ACIDS. LIGNINES. PHENYLPROPANOIDS. BENZOIC ACIDS. COUMARINS. FLAVONOIDS. TANNINS. ISOFLAVONES. TERPENOID QUINONES. MEVALONATE PATHWAY. MEVALONIC ACID BIOGENESIS. BIOSYNTHESIS OF DIFFERENT CLASSES OF TERPENES. IRIDOIDS. GIBBERELLINS. HORMONES. ANIMAL AND HUMAN STEROIDS. PHYTOSTEROLS. ALKALOIDS: DEFINITION AND NOMENCLATURE. BIOSYNTHESIS AND BIOLOGICAL ACTIVITY OF THE MAIN CLASSES OF NATURAL ALKALOIDS: COCAINE, NICOTINE, CURARE, MORPHINE, LOGANIN, LYSERGIC ACID, CONIINE. CARBOHYDRATES: GENERALITIES. CYANOGENIC GLYCOSIDES. STREPTOMYCINS. PEPTIDIC SECONDARY METABOLITES. INTERFERONS. OPIOID PEPTIDES. PEPTIDE TOXINS: RICIN AND BOTULIN. PENICILLINS. INTRODUCTION TO ENVIRONMENTAL CHEMISTRY. THE SPHERES IN WHICH THE EARTH IS DIVIDED. THE ATMOSPHERE: OZONE LAYER FORMATION AND DEPLETION; CFCS AND HALONS. OXIDANT AND POLLUTANTS SPECIES. THE GREENHOUSE EFFECT. THE KYOTO’S PROTOCOL. THE HYDROSPHERE: PHYSICAL AND CHEMICAL PROPERTIES OF WATER AND WATER BODIES. TIC, TOC, TC. EASY TO OXIDIZE ORGANIC POLLUTANTS (COD, BOD5) AND PERSISTENT ORGANIC POLLUTANTS (POP). SHORT AND LONG TERM TOXICITY (LD50 AND LOD50). NOEL AND ADI. BIOACCUMULATION AND BIO-MAGNIFICATION. METABOLISM OF A FEW PESTICIDES. (reference books) P.M. DEWICK : MEDICINAL NATURAL PRODUCTS. A BIOSYNTHETIC APPROACH. THIRD EDITION. WILEY.. C. BAIRD, M. CANN “ENVIRONMENTAL CHEMISTRY”, FIFTH EDITION. SLIDES OF THE LESSONS AND ADDITIONAL MATERIAL (PW PROTECTED) ARE AVAILABLE ON LINE AT THE ADDRESS: HTTP://HOST.UNIROMA3.IT/CENTRI/CISDIC/INDEX.HTM	6	CHIM/06	48	-	-	-	Related or supplementary learning activities	ITA
20402509 - ECOLOGY AND MANAGEMENT OF COASTAL ECOSYSTEMS (objectives) MAJOR GOALS OF THIS COURSE ARE: TO ACQUIRE AN APPROPRIATE KNOWLEDGE OF THE BIODIVERSITY AND OF GENERAL PRINCIPLES OF THE ECOLOGY OF COASTAL ECOSYSTEMS AND THEIR RELATIONSHIP WITH OTHER ECOLOGICAL BRANCHES. OTHER GOAL OF THIS COURSE IS THE GROWTH OF A THOROUGH INTEREST TO ECOLOGICAL PROBLEMS DISCUSSING THE RELATIONSHIP BETWEEN MAN AND NATURE FOCUSING IN THE COASTAL ENVIRONMENT. THE COURSE IS ALSO INTENDED TO DEVELOP BASIC INSIGHTS FOR THE ACQUISITION, ORGANIZATION AND INTERPRETATION OF ECOLOGICAL DATA RECORDED IN COASTAL ECOSYSTEMS.
20402509-1 - MODULO 1	2	BIO/03	16	-	-	-	Related or supplementary learning activities	ITA
20402509-3 - MODULO 3	2	BIO/03	-	20	-	-	Related or supplementary learning activities	ITA
20402509-2 - MODULO 2	2	BIO/05	16	-	-	-	Related or supplementary learning activities	ITA
20402510 - INLAND AND MARINE WATER ECOLOGY (objectives) The main aim is to provide a solid knowledge on both abiotic and biotic features of ecological processes considered to be common in aquatic systems. A second goal is to develop identification ability of the main aquatic species of Mediterranean systems by a comparative analysis of the different life strategies and colonization patterns of extreme habitats, and the possibility to origin more and more structured multi-species assemblanges to start ecological series. During the course, it will be introduced methods and tools to perform aquatic investigations. Students will receive information to design and execute sampling sessions on plankton, benthos e nekton, to analyze and show findings. Finally students will learn to develop applicative aspects of work in diverse issues in the field of aquatic biomonitoring and hydrobiology.
20402511 - LABORATORY OF ELECTRON AND ION BEAM MICROSCOPY APPLIED TO BIOLOGICAL SYSTEMS (objectives) THE COURSE AIMS TO PROVIDE THE STUDENT WITH BASIC KNOWLEDGE AND TECHNICAL SKILLS IN ORDER TO APPROACH THE STUDY OF BIOLOGICAL SPECIMENS BY ULTRASTRUCTURAL MORFOLOGICAL METHODOLOGIES. MAIN OBJECTIVES INCLUDE LEARNING AND APPLYING:1) BASIC PRINCIPLES OF ELECTRON MICROSCOPY; 2) METHODOLOGIES OF SAMPLE PREPARATION (PROKARYOTES AND EUKARYOTES) FOR ULTRASTRUCTURAL ANALYSIS; 3) USAGE OF DEVICES FOR ULTRASTRUCTURAL INVESTIGATION (SCNANING, TRANSMISSION AND FOCUSING ION BEAM MICROSCOPY); 3) SOFTWARE FOR MICROSCOPIC IMAGE CAPTURING AND PROCESSING 4) QUALITATIVE INTERPRETATION AND QUANTITATIVE ANALYSIS OF ULTRASTRUCTURAL DATA. THE STUDENT WILL BE ABLE TO AUTONOMOUSLY CHOOSE AND ADJUST EXPERIMENTAL PROTOCOLS, SUITED TO DIFFERENT SAMPLE TYPES AND TO THE OBJECTIVE OF THE STUDY. KNOWLEDGE ACQUIRED DURING THE COURSE WILL ALLOW THE STUDENT TO CRITICALLY ANALYZE MORPHOLOGICAL RESULTS IN A FUNCTIONAL CONTEXT.
20402511-1 - MODULO 1 - Derived from 20402511 LABORATORIO DI MICROSCOPIA ELETTRONICA E IONICA PER LO STUDIO DI SISTEMI BIOLOGICI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	3	BIO/05	8	20	-	-	Related or supplementary learning activities	ITA
20402511-2 - MODULO 2 - Derived from 20402511 LABORATORIO DI MICROSCOPIA ELETTRONICA E IONICA PER LO STUDIO DI SISTEMI BIOLOGICI in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	3	BIO/06	8	20	-	-	Related or supplementary learning activities	ITA
20402512 - METHODS AND TECHNIQUES IN VEGETATION ECOLOGY (objectives) MAJOR GOALS OF THIS COURSE ARE THE ACQUISITION OF KNOWLEDGE ON THE MAIN METHODS AND TECHNIQUES FOR THE STUDY OF VEGETATION: - ACQUIRE THE MASTERY OF THE STUDY METHODS OF VEGETATION; - INCREASE THE ABILITY TO INTERPRETING THE NATURAL AND ARTIFICIAL PHENOMENA WITH SPECIAL ATTENTION TO THE MECHANISMS OF TRANSFORMATION OF PLANT LANDSCAPES; - DEVELOP THE CAPACITY TO APPLICATION OF MOST APPROPRIATE METHODS FOR MONITORING OF THE PLANT COMMUNITIES FOR CONSERVATION AND MANAGEMENT PURPOSES; - INCREASE THE POSSIBILITIES OF INTERPRETATION OF EXPERIMENTAL DATA AND UNDERSTANDING OF SCIENTIFIC ARTICLES IN THE FIELDS OF PLANT ECOLOGY, GEOBOTANY AND APPLIED ECOLOGY.
20402512-1 - MODULO 1 - CUTINI MAURIZIO (syllabus) DEFINITION AND PROPERTIES OF PLANT COMMUNITIES. DISCRETE AND CONCRETE COMMUNITIES. ZONES AND BANDS OF VEGETATION. ZONALITY, AZONALITY AND EXTRAZONALITY. VEGETATION DYNAMICS AND POTENTIAL NATURAL VEGETATION. GROWTH FORMS AND PLANT TRAITS. ANALYSES OF THE FUNCTIONAL DIVERSITY AND GRIME’S STRATEGIES (C-S-R). DIVERSITY ANALYSES: GENERAL CONCEPT, ALGORITHMS CALCULATION, RAREFACTION CURVE, ABUNDANCE/DOMINANCE RANK, RE’NY CURVES. SAMPLING METHODS OF THE PLANT COMMUNITIES (RANDOM AND SYSTEMATIC SAMPLING). SIZE AND DISTRIBUTION OF SAMPLES. ABUNDANCE MEASURES. ORIGIN AND DEVELOPMENT OF THE PHYTOSOCIOLOGY (SYN- AND GEOSYNPHYTOSOCIOLOGY). GENERAL CONCEPT OF THE VEGETATION MAPPING. VEGETATION AND HABITAT INTERPRETATION (EUNIS AND ALL. I OF THE 92/43/CEE DIRECTIVE). HABITATS MONITORING, EUROPEAN AND NATIONAL RED LISTS OF HABITAT. MULTITEMPORAL ANALYSIS, ANTHROPIC IMPACT AND EFFECT OF VEGETATION. (reference books) BRECKLE S.W., 2002. Walter’s Vegetation of the Earth.Springer. VAN DER MAAREL E. (Ed.), 2005. Vegetation Ecology. Blackwell Publishing.	2	BIO/03	16	-	-	-	Related or supplementary learning activities	ITA
20402512-2 - MODULO 2 - ACOSTA ALICIA TERESA ROSARIO	2	BIO/03	16	-	-	-	Related or supplementary learning activities	ITA
20402512-3 - MODULO 3 - CUTINI MAURIZIO (syllabus) DEFINITION AND PROPERTIES OF PLANT COMMUNITIES. STRUCTURAL AND PHYSIOGNOMICAL CHARACTER OF VEGETATION. DISCRETE AND CONCRETE COMMUNITIES. ZONES AND BANDS OF VEGETATION. CONCEPT OF ZONALITY, AZONALITY AND EXTRAZONALITY. VEGETATION DYNAMICS AND POTENTIAL NATURAL VEGETATION.GROWTH FORMS AND PLANT TRAITS. ANALYSES OF THE FUNCTIONAL DIVERSITY AND GRIME’S STRATEGIES (C-S-R). DIVERSITY ANALYSES: GENERAL CONCEPT, ALGORITHMS CALCULATION, RAREFACTION CURVE, ABUNDANCE/DOMINANCE RANK, RE’NY CURVES. SAMPLING METHODS OF THE PLANT COMMUNITIES (RANDOM AND SYSTEMATIC SAMPLING). SIZE AND DISTRIBUTION OF SAMPLES. ABUNDANCE MEASURES. ORIGIN AND DEVELOPMENT OF THE PHYTOSOCIOLOGY AND SYMPHYTOSOCIOLOGY. GENERAL CONCEPT OF THE VEGETATION MAPPING. VEGETATION AND HABITAT INTERPRETATION (EUNIS AND ALL. I OF THE 92/43/CEE DIRECTIVE. HABITATS MONITORING, EUROPEAN AND NATIONAL RED LISTS OF HABITAT. MULTITEMPORAL ANALYSIS, ANTHROPIC IMPACT AND EFFECT OF VEGETATION. (reference books) BRECKLE S.W., 2002. Walter’s Vegetation of the Earth.Springer. VAN DER MAAREL E. (Ed.), 2005. Vegetation Ecology. Blackwell Publishing.	2	BIO/03	-	20	-	-	Related or supplementary learning activities	ITA
20402518 - TOXICOLOGY (objectives) THE COURSE AIMS TO PROVIDE PRECISE INFORMATION ON THE TOXICODYNAMIC AND TOXICOKINETIC MECHANISMS THAT ARE BEHIND THE TOXIC EFFECTS PRODUCED BY DIFFERENT NATURAL AND SYNTHESISED XENOBIOTICS, AND ON THE PROCESS OF EVALUATION OF TOXICOLOGICAL RISKS. - Derived from 20402518 TOSSICOLOGIA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 N0 TREZZA VIVIANA (syllabus) GENERAL PRINCIPLES. AIMS AND FIELDS OF TOXICOLOGY. CLASSIFICATION OF TOXIC AGENTS. MECHANISMS OF MOLECULAR AND CELL TOXICITY. RISK EVALUATION. TOXICOKINETICS: ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION OF TOXIC AGENTS. ADVERSE DRUG REACTIONS, DRUG INTERACTIONS AND PRINCIPLES OF PHARMACOVIGILANCE. ANTIDOTES AND THEIR CLASSIFICATION. EXPERIMENTAL EVALUATION OF TOXIC EFFECTS IN IN VITRO AND IN VIVO MODELS AND DATA EXTRAPOLATION. SYSTEM AND ORGAN TOXICOLOGY. DEVELOPMENTAL AND FEEDING TOXICOLOGY. CLASSES OF TOXIC COMPOUNDS: METALS, PHYTODRUGS, NATURAL TOXINS. PSYCHOACTIVE AND DOPING DRUGS. (reference books) CASARETT & DOULL'S “ESSENTIALS OF TOXICOLOGY”, SECOND EDITION, MCGRAW HILL Power-point files of the lessons will be provided To get an appointment with the Professor, email to: viviana.trezza@uniroma3.it	6	BIO/14	48	-	-	-	Related or supplementary learning activities	ITA
20402519 - APPLIED CELLULAR NEUROBIOLOGY (objectives) THE AIMS OF THIS COURSE ARE: TO GAIN KNOWLEDGE OF THE SPECIALIZED CELLULAR ARCHITECTURE OF GLIA AND NEURONS; TO DEEPEN THE KNOWLEDGE OF CELLULAR AND MOLECULAR MECHANISMS INVOLVED IN CELL COMMUNICATION, SPECIAL EMPHASIS WILL BE GIVEN TO NITRIC OXIDE-REGULATED PATHWAYS. IN THIS COURSE STUDENTS CAN USE STATE OF THE ART EQUIPMENT AND LEARN CURRENT TECHNIQUES EMPLOYED IN CELL BIOLOGY RESEARCH LABS. MOREOVER STUDENTS ARE ALLOWED TO CRITICALLY DISCUSS THE SCIENTIFIC LITERATURE IN THE FIELD OF CELL BIOLOGY.
20402519-1 - MODULO 1 - Derived from 20402519 NEUROBIOLOGIA CELLULARE APPLICATA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	4	BIO/06	32	-	-	-	Related or supplementary learning activities	ITA
20402519-2 - MODULO 2 - Derived from 20402519 NEUROBIOLOGIA CELLULARE APPLICATA in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	2	BIO/06	-	20	-	-	Related or supplementary learning activities	ITA
20402520 - PLANT BIOTECHNOLOGY FOR THE GENETIC IMPROVEMENT OF FOOD CROPS (objectives) THIS COURSE WILL PROVIDE STUDENTS WITH AN IN-DEPTH KNOWLEDGE OF PLANT TRANSFORMATION TECHNIQUES AND PLANT BIOTECHNOLOGY APPLICATIONS WITHIN AGRICULTURE AND PRODUCTION OF NEW MOLECULES. THIS COURSE WILL ALSO GIVE EDUCATION ON EMERGING TECHNOLOGIES, SUCH AS TRANSCRIPTOMICS, PROTEOMICS, METABOLOMICS, AND WILL DESCRIBE THEIR IMPORTANCE IN PLANT BIOTECHNOLOGY RESEARCH. ANOTHER IMPORTANT AIM OF THE COURSE IS TO PREPARE STUDENTS TO CONDUCT LABORATORY WORK AND RESEARCH IN THE SECTORS OF PLANT BIOTECHNOLOGY AND FOOD INDUSTRY, AS WELL AS TO CRITICALLY ANALYZE THE SCIENTIFIC INFORMATION
20402520-2 - MODULO 2 - Derived from 20402520 BIOTECNOLOGIE PER IL MIGLIORAMENTO GENETICO DELLE PIANTE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	1,5	BIO/04	-	15	-	-	Related or supplementary learning activities	ITA
20402520-1 - MODULO 1 - Derived from 20402520 BIOTECNOLOGIE PER IL MIGLIORAMENTO GENETICO DELLE PIANTE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) THREE ARE THE MAIN ARGUMENTS OF THE COURSE: GENE TRANSFER TECHNIQUES; APPLICATIONS OF PLANT BIOTECHNOLOGY; ANALYSIS OF RISKS AND BENEFITS OF PLANT GENETIC MANIPULATION.IN DETAIL, DURING THE COURSE THE FOLLOWING ARGUMENTS ARE DISCUSSED:TECHNIQUES FOR GENE TRANSFER INTO THE NUCLEAR AND CHLOROPLASTIC GENOME; TECHNIQUES FOR IN VITRO CULTURE OF PLANT CELLS; USE OF SELECTABLE GENE MARKERS AND REPORTER GENES; STRATEGIES TO REMOVE SELECTABLE GENE MARKERS FROM TRANSGENIC PLANTS; INDUCIBLE EXPRESSION OF TRANSGENES IN PLANTS; TRANSIENT EXPRESSION OF GENES IN PLANTS; GENE SILENCING IN PLANTS; ‘GENE TARGETING’ IN PLANTS; GENOME EDITINGIN IN PLANTS; PLANTS WITH IMPROVED NUTRITIONAL VALUE; PRODUCTION OF ANTIBODIES AND VACCINES IN TRANSGENIC PLANTS; BIOTECHNOLOGICAL STRATEGIES TO OBTAIN PLANTS RESISTANT TO HERBICIDES, PATHOGENS AND ENVIRONMENTAL STRESSES; PLANTS WITH INCREASED PHOTOSYNTHETIC RATE; BIOSAFETY AND BIOETHICAL ISSUES RELATED TO PLANT BIOTECHNOLOGY; EMERGING TECHNOLOGIES AND PLANT BIOTECHNOLOGY. (reference books) -Recommended textbooks:1. BIOCHEMISTRY AND MOLECULAR BIOLOGY OF PLANTS (2000) BUCHANAN B.B, GRUISSEM W., JONES R.L., AMERICAN SOCIETY OF PLANT PHYSIOLOGISTS, ROCKVILLE, MARYLAND.2. BIOLOGIA CELLULARE E BIOTECNOLOGIE VEGETALI (2011) COZZOLINO S., DI SANSEBASTIANO G.P., FORNI C., GENRE A., LANFRANCO L., MICCHELI A., PASQUA G., TRAINOTTI L., VALLETTA A.3. HANDBOOK OF PLANT BIOYECHNOLOGY (2004) CHRISTOU P., KLEE H., HOBOKEN, (N.J.), WILEY.4. PLANT BIOTECHNOLOGY AND TRANSGENIC PLANTS (2002) OKSMAN-CALDENTEY K.-M., BARZ W.H., NEW YORK, DEKER.-Scientific articles published in international journals (pdf files will be provided).-Lecture notes will be provided.	4,5	BIO/04	36	-	-	-	Related or supplementary learning activities	ITA
20402521 - MOLECULAR ENDOCRINOLOGY (objectives) ENDOCRINOLOGY IS USUALLY TAUGHT AT THE END OF STANDARD PHYSIOLOGY COURSES, BECAUSE THE ENDOCRINE SYSTEM REGULATES ALL THE OTHER ORGAN SYSTEMS. IN THIS RESPECT, LEARNING ABOUT ENDOCRINE SYSTEM HAS THE ADDED CHALLENGE OF INTEGRATING STUDENT KNOWLEDGE OF HORMONES AND THEIR ACTIONS WITH THE GENERAL FUNCTION OF A SPECIFIC ORGAN SYSTEM. THE MAIN OBJECTIVES OF THIS COURSE ARE TO ALLOW THE STUDENT TO GAIN A FOUNDATION OF KNOWLEDGE ABOUT THE ENDOCRINE SYSTEM AND INTEGRATIVE PHYSIOLOGY, TO BECOME REFINED IN THE CRITICAL ANALYSIS OF SCIENTIFIC PAPERS RELATED TO ENDOCRINE PHYSIOLOGY, TO DEVELOP PROBLEM SOLVING AND PUBLIC SPEAKING TECHNIQUES.
20402522 - DEVELOPMENTAL NEUROBIOLOGY (objectives) THE MAIN GOAL IS TO PROVIDE ADVANCED KNOWLEDGE IN DEVELOPMENTAL BIOLOGY, WITH SPECIAL REFERENCE TO THE NERVOUS SYSTEM. THE CELLULAR AND MOLECULAR MECHANISMS UNDERLYING NERVOUS TISSUE DIFFERENTIATION AND MORPHOGENESIS WILL BE ADDRESSED IN DIFFERENT IN VIVO MODELS. LIFE-LONG FUNCTIONAL IMPLICATIONS OF NEUROGENESIS AND PLASTICITY WILL BE EMPHASIZED. THE STUDENT WILL BE ABLE TO: 1) DESCRIBE DEVELOPMENTAL PROCESSES OF INVERTEBRATE AND VERTEBRATE NERVOUS SYSTEM; 2) RECOGNISE MOLECULAR PATHWAYS DIRECTING STEM CELLS TOWARDS NEURONAL/GLIAL CELL DIFFERENTIATION; 3) CORRELATE ONTOGENETIC ABNORMALITIES WITH SPECIFIC NEUROLOGICAL DISTURBANCES, INCLUDING INFANTILE DISEASES AND AGE-RELATED NEURODEGENERATION.
20402522-1 - MODULO 1 - Derived from 20402522 NEUROBIOLOGIA DELLO SVILUPPO in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	5	BIO/06	40	-	-	-	Related or supplementary learning activities	ITA
20402522-2 - MODULO 2 - Derived from 20402522 NEUROBIOLOGIA DELLO SVILUPPO in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) Main goal of the course is to provide advanced knowledge in developmental biology, with special reference to vertebrate nervous system. The cellular and molecular mechanisms underlying nervous tissue differentiation and morphogenesis will be addressed in different in vivo and in vitro models. Life-long functional implications of neurogenesis and plasticity will be emphasized. Upon completion of the course, the student will acquire: 1) Knowledge of neurodevelopmental processes of vertebrate nervous system; 2) Knowledge of the principal molecular pathways of neurogenesis; 3) Ability to correlate ontogenetic abnormalities with specific neurological disturbances, including infantile diseases and age-related neurodegeneration;4) Competence in recognizing mammalian neurodevelopmental stages, by observation of synthetic models or histological slides;5) Competence in utilizing morphological techniques (immunohistochemistry, immunofluorescence, electron microscopy), to characterize mammalian brain at different stages.Program of lectures and lab sessionsOverview of developmental processes of pluricellular organisms. Germ cell layers. Ectodermal derivation of neural tissue in invertebrates e vertebrates. Specification of neuroectoderm and neurulation process in vertebrates. Primary neurulation: cellular e molecular mechanisms of neural plate, folds, furrow, and tube formation. Secondary neurulation. Neural tube defects in mammals: genetic and environmental causes of anencephaly and spina bifida. Morphogenesis and differentiation of the encephalon and spinal cord. Role of cell death in the morphogenesis of the central nervous system: apoptotic and autophagic pathways. Neural crest: specification and regionalization. Cell migration and differentiation of cephalic, cardiac, trunk, vagal e sacral neural crest. Multipotency e plasticity of neural crest cells. Layering of cortical structures in the cerebrum and cerebellum. Congenital diseseases associated with defects to neuronal migration: the case of peroxisomal disorders. Neural stem cells: neuronal and glial differentiation. Adult neurogenesis in mammals: the subventricular and subgranular zones. The concept of stem cell niche. Regulatory pathways of the neurogenic niche. Neurogenesis and neurodegeneration in the senescent brain. Age-related neurodegenerative diseases: common and specific features. Protein aggregates, role of apoptotic and autophagic pathways, and stem cell-based therapies against neurodegeneration. (reference books) GILBERT: "DEVELOPMENTAL BIOLOGY", SINAUER ASSOCIATES, INC.SANES ET AL.: "DEVELOPMENT OF THE NERVOUS SYSTEM", ELSEVIER INC.	1	BIO/06	-	10	-	-	Related or supplementary learning activities	ITA
20402523 - MOLECULAR AND CELLULAR PHYSIOLOGY (objectives) ON THE BASIS OF THE MOST RECENT SCIENTIFIC LITERATURE, THE COURSE IS AIMED TO ALLOW THE STUDENTS TO UNDERSTAND SOME ASPECTS OF THE REGULATION OF CELLULAR FUNCTIONS
20402523-1 - MODULO 1 - Derived from 20402523 FISIOLOGIA CELLULARE E MOLECOLARE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire)	5	BIO/09	40	-	-	-	Related or supplementary learning activities	ITA
20402523-2 - MODULO 2 - Derived from 20402523 FISIOLOGIA CELLULARE E MOLECOLARE in BIOLOGIA PER LA RICERCA MOLECOLARE, CELLULARE E FISIOPATOLOGICA (DM 270) LM-6 (docente da definire) (syllabus) MECHANISMS OF CELL FUNCTION REGULATION: PHOSPHORYLATION- AND UBIQUITINATION-BASED INTRACELLULAR SIGNALLING; TYROSIN-KINASES AND NUCLEAR RECEPTORS AS MODULATORS OF CELLULAR FUNCTIONS (2,5 CFU).REGULATION OF THE MOLECULAR MECHANISMS OF ENDOCYTOSIS, CELL CYCLE, GENE TRANSCRIPTION, CELL MOTILITY AND CELL MIGRATION (2,5 CFU).REGULATION OF SOME ASPECTS OF THE LIPID AND SUGAR METABOLISM WITH PARTICOLAR FOCUS ON SOME SPECIFIC REGULATORY ENZYMES (AMPK, CHOLESTEROL SENSORS) (1 CFU). (reference books) NO REFERENCE BOOK. MATERIAL IS SUPPLIED DURING LECTURES BY THE PROFESSOR.	1	BIO/09	-	10	-	-	Related or supplementary learning activities	ITA

Optional group: ALTRO - (show)

20410001 - A SCELTA DELLO STUDENTE

120

Elective activities

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20402230 - PROVA FINALE

420

Final examination and foreign language test

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