SGURA ANTONELLA
(syllabus)
Basic knowledges on the Genetics of eucaryotes and procariotes. Knowledges on the methodology used in genetics, experimental model and experimental design.
DNA AS GENETIC MATERIAL; SEMICONSERVATIVE DNA REPLICATION IN PROKARYOTES (MESELSON AND STAHL EXPERIMENT) AND EUKARYOTES (TAYLOR’S EXPERIMENT); MENDELIAN GENETICS; GENOTYPE AND PHENOTYPE;PRINCIPLES OF SEGREGATION AND INDEPENDENT ASSORTMENT; DOMINANT AND RECESSIVE TRAITS; CHROMOSOMAL BASIS OF INHERITANCE; MEIOSIS AND MENDELIAN PRINCIPLES; SEX CHROMOSOME AND SEX DETERMINATION; EXTENTIONS OF AND DEVIATIONS FROM MENDELIAN GENETIC PRINCIPLES; MULTIPLE ALLELES; MODIFICATIONS OF DOMINANCE RELATIONSHIP; RICOMBINATION; GENETIC MAPPING IN EUKARYOTES. GENE MAPPING IN BACTERIA AND BACTERIOPHAGES; BENZER’S EXPERIMENTS; COMPLEMENTATION; TRANSLATION; THE GENETIC CODE; GENE FUNCTION; REGULATION OF GENE EXPRESSION IN BACTERIA; DNA MUTATIONS; VARIATIONS IN CHROMOSOME STRUCTURE AND NUMBER;QUANTITATIVE GENETICS; POPULATION GENETICS: THE HARDY WEINNBERG LAW; FORCES THAT CHANGE GENE FREQUENCIES IN POPULATIONS; EVOLUTION
Practical work in the lab, with dedicated slides on mitoses; Genetics association and genetic map of 3 genes
(reference books)
- P.J. RUSSEL GENETICA: UN APPROCCIO MOLECOLARE (PEARSONS ) - R.J. BROOKER. GENETICA, ANALISI E PRINCIPI. ( ZANICHELLI ) - D.P.SNUSTAD,M.J.SIMMONS PRINCIPI DI GENETICA
Students are received on fridays: 14.00-16.00
In order to deeply involve the students, during the lessons they are invited to solve easy exercises alone or in small groups
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