Università Roma Tre

THE COURSE CONCERNS THE GENERAL UNDERSTANDING OF THE MOLECULAR MECHANISMS WHICH REGULATE THE BIOLOGICAL PROCESSES OCCURRING WITHIN A CELL, WITH PARTICULAR EMPHASYS ON GENETIC STRUCTURE, ORGANIZATION AND GENE EXPRESSION. THE MOST ADVANCED MOLECULAR BIOLOGY METHODOLOGIES UTILIZED IN BASIC AND APPLIED SCIENCE WILL BE TAKEN INTO CONSIDERATION. THE COURSE IS DIVIDED INTO THE FOLLOWING ISSUES: GENOME CONTENT; GENOME SEQUENCES AND GENE NUMBER; GENE FAMILIES AND REPETITIVE SEQUENCES; MESSENGER RNA; PROTEIN SYNTHESIS; GENETIC CODE USAGE; TRANSCRITION; OPERONS; PHAGE BIOGENESIS; REPLICON; EXTRACHROMOSAL REPLICONS; REPLICATION; RECOMBINATION; TRANSPOSONS; RTEROVIRUS AND RETROTRANSPOSONS; PROMOTERS AND ENHANCERS; TRANSCRIPTION REGULATION IN EUKARYOTS; RNA MATURATION AND SPLICING; CATALYTIC RNA; CHROMOSOMES; NUCLEOSOMES AND CHROMATIN; EPIGENETIC EFFECTS.

TEXTBOOK: ZLATANOVA E VAN HOLDE - BIOLOGIA MOLECOLARE - STRUTTURA E DINAMICA DI GENOMI E PROTEOMI - ZANICHELLI.