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20401662 PHARMACOLOGY in Biology for Molecular, Cellular and Physiopathological Research LM-6 N0 TREZZA VIVIANA
(syllabus)
INTRODUCTION: NATURE OF DRUGS, DRUG NOMENCLATURE, DRUG CLASSIFICATION. CLINICAL AND PRECLINICAL PHARMACOLOGY. PRINCIPLES OF GENERAL PHARMACOLOGY- PHARMACOKINETICS: THE DYNAMICS OF DRUG ABSORPTION, DISTRIBUTION, BIOTRANSFORMATION AND ELIMINATION. MAIN PHARMACOKINETIC PARAMETERS. PHARMACODYNAMICS: MECHANISMS OF DRUG ACTION; DRUG RECEPTORS; DRUG-RECEPTOR INTERACTIONS; SIGNAL TRANSDUCTION MECHANISMS; AGONISTS AND ANTAGONISTS. NEUROTRANSMITTERS. SYSTEMATIC PHARMACOLOGY- MECHANISM OF ACTION, THERAPEUTIC EFFECTS AND SIDE EFFECTS OF THE MAIN CLASSES OF DRUGS: AUTONOMIC DRUGS; DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM; CARDIOVASCULAR DRUGS; ANTI-INFLAMMATORY DRUGS; BRONCHODILATORS AND OTHER DRUGS USED IN ASTHMA; DRUGS USED IN GASTROINTESTINAL DISORDERS; CANCER CHEMOTHERAPY; ANTIMICROBIC DRUGS.
(reference books)
Clark, Finkel, Rey, Whalen. “Pharmacology", Lippincott's Illustrated Reviews, 5th Edition
Power-point files of the lessons will be provided To get an appointment with the Professor, email to: viviana.trezza@uniroma3.it
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