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20410314 GENETICA DEI SISTEMI COMPLESSI in Biology for Molecular, Cellular and Physiopathological Research LM-6 Berardinelli Francesco
(syllabus)
GENOME (ORGANIZATION, STRUCTURE AND FUNCTION, THE EXOME AND THE GENETIC REGULATION OF GENE TRANSCRIPTION). EPIGENOME (METHYLATION, HISTONE CODE, CHROMATIN 3D ARCHITECTURE, NON-CODING RNA). GENETIC MECHANISMS OF SEX DETERMINATION (HOW DOES SEX IS GENETICALLY DETERMINED, INACTIVATION OF X CHROMOSOME, SEX-DEPENDENT PHONOTYPIC EFFECTS). CELL CYCLE REGULATION. GENETIC OF AGING (GENETIC THEORIES OF AGING, GERONTOGENES AND GENES INVOLVED IN LONGEVITY, AGING IN ANIMAL MODELS, MOLECULAR AND CELLULAR AGING). CANCER GENETICS (ONCOGENES, ONCO-SUPPRESSOR GENES, CHROMOSOMAL REARRANGEMENTS INVOLVED IN CANCER, THE CANCER STEM CELLS THEORY). INDIVIDUAL GENETIC RESPONSE AND PHARMACOGENETICS.
(reference books)
- SCIENTIFIC ARTICLES AND DISPENSES PROVIDED BY THE PROFESSOR - TOM STRACHAN E ANDREW READ, GENETICA MOLECOLARE UMANA, ZANICHELLI - MICHEAL R. CUMMINGS, EREDITA’ PRINCIPI E PROBLEMATICHE DELLA GENETICA UMANA, EDISES - DANIEL L. HARTL ED ELIZABETH W. JONES, GENETICA ANALISI DI GENI E GENOMI, EDISES - M.A. JOBLING, M.E. HURLES E C. TYLER-SMITH, HUMAN EVOLUTIONARY GENETICS, GARLAND SCIENCE
The professor receives every Tuesday from 16.00 to 17.00 by appointment via email: francesco.berardinelli@uniroma3.it
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