(objectives)
THE COURSE AIM TO PROVIDE A WIDER AND DEEPER OUTLOOK OF GENETICS TOPICS NOT ADDRESSED IN THE COURSE OF GENETICS. SPECIAL ATTENTION WILL BE PAIED TO THE ROLE OF HUMAN GENOME (AND EPIGENOME) IN THE REGULATION OF COMPLEX BIOLOGICAL PROCESSES AND IN THE INDIVIDUAL RESPONSE TO ENDOGENOUS AND EXOGENOUS FACTORS.
|
Code
|
20410171 |
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Module:
(objectives)
THE COURSE AIM TO PROVIDE A WIDER AND DEEPER OUTLOOK OF GENETICS TOPICS NOT ADDRESSED IN THE COURSE OF GENETICS. SPECIAL ATTENTION WILL BE PAIED TO THE ROLE OF HUMAN GENOME (AND EPIGENOME) IN THE REGULATION OF COMPLEX BIOLOGICAL PROCESSES AND IN THE INDIVIDUAL RESPONSE TO ENDOGENOUS AND EXOGENOUS FACTORS.
|
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Credits
|
5
|
Scientific Disciplinary Sector Code
|
BIO/18
|
Contact Hours
|
40
|
Type of Activity
|
Related or supplementary learning activities
|
Teacher
|
Berardinelli Francesco
(syllabus)
GENOME (ORGANIZATION, STRUCTURE AND FUNCTION, THE EXOME AND THE GENETIC REGULATION OF GENE TRANSCRIPTION). EPIGENOME (METHYLATION, HISTONE CODE, CHROMATIN 3D ARCHITECTURE, NON-CODING RNA). GENETIC MECHANISMS OF SEX DETERMINATION (HOW DOES SEX IS GENETICALLY DETERMINED, INACTIVATION OF X CHROMOSOME, SEX-DEPENDENT PHENOTYPIC EFFECTS). CELL CYCLE REGULATION. GENETIC OF AGING (GENETIC THEORIES OF AGING, GERONTOGENES AND GENES INVOLVED IN LONGEVITY, AGING IN ANIMAL MODELS, MOLECULAR AND CELLULAR AGING). CANCER GENETICS (ONCOGENES, ONCO-SUPPRESSOR GENES, CHROMOSOMAL REARRANGEMENTS INVOLVED IN CANCER, THE CANCER STEM CELLS THEORY). INDIVIDUAL GENETIC RESPONSE (PHARMACOGENETICS, NUTRIGENETICS AND NUTRIGENOMICS). MITOCHONDRIAL DNA (ORGANIZATION OF MITOCHONDRIAL DNA, EXTRANUCLEAR INHERITANCE). MOLECULAR EVOLUTION OF GENES AND GENOMES.
(reference books)
- ARTICOLI SCIENTIFICI E DISPENSE FORNITE DAL DOCENTE - TOM STRACHAN E ANDREW READ, GENETICA MOLECOLARE UMANA, ZANICHELLI - MICHEAL R. CUMMINGS, EREDITA’ PRINCIPI E PROBLEMATICHE DELLA GENETICA UMANA, EDISES - DANIEL L. HARTL ED ELIZABETH W. JONES, GENETICA ANALISI DI GENI E GENOMI, EDISES - M.A. JOBLING, M.E. HURLES E C. TYLER-SMITH, HUMAN EVOLUTIONARY GENETICS, GARLAND SCIENCE
Il professore riceve tutti martedì dalle 16.00 alle 17.00 previo appuntamento via mail: francesco.berardinelli@uniroma3.it
|
Dates of beginning and end of teaching activities
|
From to |
Delivery mode
|
Traditional
|
Attendance
|
not mandatory
|
Evaluation methods
|
Oral exam
|
|
|
Module:
(objectives)
THE COURSE AIM TO PROVIDE A WIDER AND DEEPER OUTLOOK OF GENETICS TOPICS NOT ADDRESSED IN THE COURSE OF GENETICS. SPECIAL ATTENTION WILL BE PAIED TO THE ROLE OF HUMAN GENOME (AND EPIGENOME) IN THE REGULATION OF COMPLEX BIOLOGICAL PROCESSES AND IN THE INDIVIDUAL RESPONSE TO ENDOGENOUS AND EXOGENOUS FACTORS.
|
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Credits
|
1
|
Scientific Disciplinary Sector Code
|
BIO/18
|
Contact Hours
|
-
|
Laboratory Hours
|
10
|
Type of Activity
|
Related or supplementary learning activities
|
Teacher
|
Berardinelli Francesco
(syllabus)
GENOME (ORGANIZATION, STRUCTURE AND FUNCTION, THE EXOME AND THE GENETIC REGULATION OF GENE TRANSCRIPTION). EPIGENOME (METHYLATION, HISTONE CODE, CHROMATIN 3D ARCHITECTURE, NON-CODING RNA). GENETIC MECHANISMS OF SEX DETERMINATION (HOW DOES SEX IS GENETICALLY DETERMINED, INACTIVATION OF X CHROMOSOME, SEX-DEPENDENT PHENOTYPIC EFFECTS). CELL CYCLE REGULATION. GENETIC OF AGING (GENETIC THEORIES OF AGING, GERONTOGENES AND GENES INVOLVED IN LONGEVITY, AGING IN ANIMAL MODELS, MOLECULAR AND CELLULAR AGING). CANCER GENETICS (ONCOGENES, ONCO-SUPPRESSOR GENES, CHROMOSOMAL REARRANGEMENTS INVOLVED IN CANCER, THE CANCER STEM CELLS THEORY). INDIVIDUAL GENETIC RESPONSE (PHARMACOGENETICS, NUTRIGENETICS AND NUTRIGENOMICS). MITOCHONDRIAL DNA (ORGANIZATION OF MITOCHONDRIAL DNA, EXTRANUCLEAR INHERITANCE). MOLECULAR EVOLUTION OF GENES AND GENOMES.
(reference books)
- ARTICOLI SCIENTIFICI E DISPENSE FORNITE DAL DOCENTE - TOM STRACHAN E ANDREW READ, GENETICA MOLECOLARE UMANA, ZANICHELLI - MICHEAL R. CUMMINGS, EREDITA’ PRINCIPI E PROBLEMATICHE DELLA GENETICA UMANA, EDISES - DANIEL L. HARTL ED ELIZABETH W. JONES, GENETICA ANALISI DI GENI E GENOMI, EDISES - M.A. JOBLING, M.E. HURLES E C. TYLER-SMITH, HUMAN EVOLUTIONARY GENETICS, GARLAND SCIENCE
Il professore riceve tutti martedì dalle 16.00 alle 17.00 previo appuntamento via mail: francesco.berardinelli@uniroma3.it
|
Dates of beginning and end of teaching activities
|
From to |
Delivery mode
|
Traditional
|
Attendance
|
not mandatory
|
Evaluation methods
|
Oral exam
|
|
|
|