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Teacher
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AFFABRIS ELISABETTA
(syllabus)
Module 1:The course describes and compares the replication cycles of different animal viruses that infect vertebrate hosts to gain insight into: origin of viruses, structure, evolution, virus-cell interactions, host defense mechanisms and strategies of viral immunoevasion, methods of detection, identification and titration, antiviral drugs and profilaxis of viral infections. In particular, it will be described viruses of the following viral families: picornaviridae, ortomixoviridae, paramixoviridae, rabdoviridae, retroviridae, hepadnaviridae, flaviviridae, parvoviridae, poliomaviridae, papillomaviridae, adenoviridae, herpesviridae, poxviridae. Students will be able to apply the acquired knowledge to understand in-depth texts and experimental data related to the discipline.
(reference books)
WHERE TO STUDY:
Adopted text book:
- Leonard Norkin – Virology: Molecular Biology and Pathogenesis - ASM (American Society for Microbiology) Press
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- Fields virology, Vth edition, 2007- D.M.Knipe and P.M.Howley editors-in-chief -Lippincot Williams & Wilkins publishers, cap.16 Viral vectors and their applications (to study adenoviral, adeno-associated, retroviral and lentiviral vectors + oncolitic adenoviruses)
- Stéphanie Durand and Andrea Cimarelli - The Inside Out of Lentiviral Vectors - Viruses 2011, 3, 132-159.
It is available a CD with supplementary materials at the box office of “segreteria didattica biologia“
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Università Roma Tre