(objectives)
PROVIDE THE STUDENT KNOWLEDGE THEORY AND PRACTICES THAT MAKE COMPETENT AND CAPABLE OF APPLIED TECHNOLOGIES OF CLASSIC CYTOGENETICS (VARIOUS TYPES OF BANDING) THAT MOST OF MODERN TECHNOLOGY (FISH, CGH) IN HIGHER ORGANISMS EUKARYOTES.
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Code
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20401221 |
Language
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ITA |
Type of certificate
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Profit certificate
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Module: |
Code
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20401221-2 |
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Credits
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3
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Scientific Disciplinary Sector Code
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BIO/18
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Contact Hours
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-
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Laboratory Hours
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30
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Type of Activity
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Related or supplementary learning activities
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Derived from
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20401221 MOLECULAR GENETIC AND CYTOGENETIC TECHNIQUES in Biology for Molecular, Cellular and Physiopathological Research LM-6 (professor to define)
(syllabus)
THE COURSE IN TWO PARTS, A THEORY AND PRACTICE (IN ITALICS AND BOLD) STRONGLY ASSOCIATED WITH EACH OTHER.
- THE FIRST STUDY ON CHROMOSOME, HAPLOID, DIPLOID, CELL CYCLE, MITOSIS, MEIOSIS AND THE BEGINNING OF CYTOGENETICS - STRUCTURAL ELEMENTS OF CHROMOSOME EUKARYOTIC DNA ORGANIZATION IN CHROMOSOMES, CHROMOSOME SCAFFOLD AND NUCLEAR MATRIX, EUCHROMATIN AND HETEROCHROMATIN. X-CHROMOSOME INACTIVATION COMPLEXITY 'GENOME EUKARYIOTIC - USE OF DATABASES AS A SUPPORT TO TRIAL IN GENETICS
- SETTING UP PREPARATIONS METAPHASE
- THE CENTROMERE, THE CENTROMERIC DNA FROM YEAST MAN, HUMAN SATELLITE DNA, CENTROMERE PROTEINS CONSTITUENT. CENTROMERE PROTEINS OPTIONAL
- IMMUNOLOGICAL AND MOLECULAR TECHNIQUES TO HIGHLIGHT THE CENTROMERIC REGIONS
- TELOMERE STRUCTURE: TELOMERIC SEQUENCE AND THE ROLE OF TELOMERIC PROTEIN, FUNCTION: MITOTIC CLOCK AND MAINTAINING THE STABILITY 'GENOMICS.
- MOLECULAR TECHNIQUES TO HIGHLIGHT THE TELOMERES
- FORENSIC GENETICS AND DETERMINATION OF PATERNITY ' - STRUCTURAL CHROMOSOME ABERRATIONS AND NUMERICAL ORIGINATE 'de novo' (LEUKEMIA) OR TRANSMITTED BY HEREDITARY (GENETIC SYNDROMES)
- BANDING TECHNIQUES MODERN AND TECHNIQUES TO PUT IN EVIDENCE AND CHROMOSOMES KARYOTYPES - TECHNIQUES IN MOLECULAR GENETIC DIAGNOSIS OF LEUKEMIA
* TWO EXERCISES MAY BE CARRIED OUT AT THE HOSPITAL STRUCTURE OF GENERAL HOSPITAL OF TOR VERGATA
(reference books)
T.D.POLLARD, W.C.EARNSHAW: CELL BIOLOGY, SAUNDERS, 2002 CAPITOLO 12: CHROMOSOME ORGANIZATION CHAPTER 13: DNA PACKAGING IN CHROMATIN AND CHROMOSOMES
SUMNER A.T.: CHROMOSOMES: ORGANIZATION AND FUNCTION, BLACKWELL, 2003 CHAPTER 7: CONSTITUTIVE HETEROCHROMATIN
TURNER B. M. CHROMATIN AND GENE REGULATION, BLACKWELL SCIENCE, 2001 CHAPTER 12: MECHANISMS OF DOSAGE COMPENSATION, P. 249-261.
CLEVELAND D.W., MAO, SULLIVAN: CENTROMERE AND KINETOCHORES: FROM EPIGENETICS TO MITOTIC CHECKPOINT SIGNALING, CELL, 112, 407- 421. (2003)
WATRIN E. AND LEGAGNEUX V. INTRODUCTION TO CHROMOSOME DYNAMICS AT MITOSIS. BIOLOGY OF THE CELL 95 507-513 (2003)
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Dates of beginning and end of teaching activities
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From 01/03/2016 to 20/06/2016 |
Attendance
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not mandatory
|
|
|
Module: |
Code
|
20401221-1 |
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Credits
|
3
|
Scientific Disciplinary Sector Code
|
BIO/18
|
Contact Hours
|
24
|
Type of Activity
|
Related or supplementary learning activities
|
Derived from
|
20401221 MOLECULAR GENETIC AND CYTOGENETIC TECHNIQUES in Biology for Molecular, Cellular and Physiopathological Research LM-6 (professor to define)
(syllabus)
THE COURSE IN TWO PARTS, A THEORY AND PRACTICE (IN ITALICS AND BOLD) STRONGLY ASSOCIATED WITH EACH OTHER.
- THE FIRST STUDY ON CHROMOSOME, HAPLOID, DIPLOID, CELL CYCLE, MITOSIS, MEIOSIS AND THE BEGINNING OF CYTOGENETICS - STRUCTURAL ELEMENTS OF CHROMOSOME EUKARYOTIC DNA ORGANIZATION IN CHROMOSOMES, CHROMOSOME SCAFFOLD AND NUCLEAR MATRIX, EUCHROMATIN AND HETEROCHROMATIN. X-CHROMOSOME INACTIVATION COMPLEXITY 'GENOME EUKARYIOTIC - USE OF DATABASES AS A SUPPORT TO TRIAL IN GENETICS
- SETTING UP PREPARATIONS METAPHASE
- THE CENTROMERE, THE CENTROMERIC DNA FROM YEAST MAN, HUMAN SATELLITE DNA, CENTROMERE PROTEINS CONSTITUENT. CENTROMERE PROTEINS OPTIONAL
- IMMUNOLOGICAL AND MOLECULAR TECHNIQUES TO HIGHLIGHT THE CENTROMERIC REGIONS
- TELOMERE STRUCTURE: TELOMERIC SEQUENCE AND THE ROLE OF TELOMERIC PROTEIN, FUNCTION: MITOTIC CLOCK AND MAINTAINING THE STABILITY 'GENOMICS.
- MOLECULAR TECHNIQUES TO HIGHLIGHT THE TELOMERES
- FORENSIC GENETICS AND DETERMINATION OF PATERNITY ' - STRUCTURAL CHROMOSOME ABERRATIONS AND NUMERICAL ORIGINATE 'de novo' (LEUKEMIA) OR TRANSMITTED BY HEREDITARY (GENETIC SYNDROMES)
- BANDING TECHNIQUES MODERN AND TECHNIQUES TO PUT IN EVIDENCE AND CHROMOSOMES KARYOTYPES - TECHNIQUES IN MOLECULAR GENETIC DIAGNOSIS OF LEUKEMIA
* TWO EXERCISES MAY BE CARRIED OUT AT THE HOSPITAL STRUCTURE OF GENERAL HOSPITAL OF TOR VERGATA
(reference books)
T.D.POLLARD, W.C.EARNSHAW: CELL BIOLOGY, SAUNDERS, 2002 CAPITOLO 12: CHROMOSOME ORGANIZATION CHAPTER 13: DNA PACKAGING IN CHROMATIN AND CHROMOSOMES
SUMNER A.T.: CHROMOSOMES: ORGANIZATION AND FUNCTION, BLACKWELL, 2003 CHAPTER 7: CONSTITUTIVE HETEROCHROMATIN
TURNER B. M. CHROMATIN AND GENE REGULATION, BLACKWELL SCIENCE, 2001 CHAPTER 12: MECHANISMS OF DOSAGE COMPENSATION, P. 249-261.
CLEVELAND D.W., MAO, SULLIVAN: CENTROMERE AND KINETOCHORES: FROM EPIGENETICS TO MITOTIC CHECKPOINT SIGNALING, CELL, 112, 407- 421. (2003)
WATRIN E. AND LEGAGNEUX V. INTRODUCTION TO CHROMOSOME DYNAMICS AT MITOSIS. BIOLOGY OF THE CELL 95 507-513 (2003)
|
Dates of beginning and end of teaching activities
|
From 01/03/2016 to 20/06/2016 |
Attendance
|
not mandatory
|
|
|
|