Derived from
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20401821 IMMUNOLOGY in Biology for Molecular, Cellular and Physiopathological Research LM-6 N0 DI ROSA FRANCESCA
(syllabus)
LYMPHOID ORGANS: BONE MARROW, THYMUS, LYMPH NODES AND LYMPHATIC SYSTEM, SPLEEN, MUCOSE ASSOCIATED LYMPHOID SYSTEM. B LYMPHOCYTE DEVELOPMENT: SELECTION AND MATURATION OF B CELLS. IMMUNOGLOBULIN STRUCTURE AND IMMUNOGLOBULIN GENE REARRANGEMENT. T LYMPHOCYTE DEVELOPMENT: SELECTION AND MATURATION OF T CELLS. TCR STRUCTURE AND TCR GENE REARRANGEMENT. ANTIGEN PRESENTING CELLS AND INNATE IMMUNITY RECEPTORS. MHC: GENES AND PROTEINS. ANTIGEN PROCESSING. INDUCTION OF PRIMARY RESPONSE: DENDRITIC CELL ACTIVATION, INDUCTION OF ANTIGEN-SPECIFIC RESPONSE OF T AND B LYMPHOCYTES. CYTOKINES: GENERAL CHARACTERISTICS CYTOKINES REGULATING INNATE IMMUNITY, CYTOKINES REGULATING ANTIGEN-SPECIFIC IMMUNITY. IL-1 SUPERFAMILY, INFLAMMOSOME; TNF SUPERFAMILY. CHEMOKINES: GENERAL CHARACTERISTICS, INFLAMMATORY AND HOMEOSTATIC CHEMOKINES. IMMUNITY AGAINST INFECTIONS. IMMUNOLOGICAL MEMORY AND VACCINES. TOLERANCE AND AUTOIMMUNITY: CENTRAL AND PERIPHERAL TOLERANCE, BREKING OF TOLERANCE, AUTOIMMUNITY AND DISEASES. ALLERGIES: CAUSES AND TYPES OF HYPERSENSIBILITY DISEASES. PRIMARY AND SECONDARY IMMUNODEFICIENCIES: GENERAL CHARACTERISTICS, CLASSIFICATION, GENE THERAPY EXAMPLES. MAIN CONCEPTS ON ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS). TUMORS AND IMMUNITY: TUMORAL ANTIGENS, IMMUNE RESPONSE TO TUMORS, IMMUNOTHERAPY AND VACCINATION AGAINST TUMORS. TRANSPLANTATION: ANTI-GRAFT IMMUNE RESPONSE, EFFECTOR MECHANISMS, BIOTECHNOLOGICAL TOOLS FOR INTERVENTION.
(reference books)
K. MURPHY. , IMMUNOBIOLOGIA DI JANEWAY , 8° EDIZIONE, PICCIN, 2012. A.K. ABBAS, A. H. LICHTMAN, S. PILLAI , IMMUNOLOGIA CELLULARE E MOLECOLARE , 7° EDIZIONE, ELSEVIER MASSON, 2012. TAK. W. MAK, M. SAUNDERS, FONDAMENTI DI IMMUNOLOGIA, ZANICHELLI, 2012
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