Università Roma Tre

INTRODUCTION: NATURE OF DRUGS, DRUG NOMENCLATURE, DRUG CLASSIFICATION. CLINICAL AND PRECLINICAL PHARMACOLOGY.
PRINCIPLES OF GENERAL PHARMACOLOGY- PHARMACOKINETICS: THE DYNAMICS OF DRUG ABSORPTION, DISTRIBUTION, BIOTRANSFORMATION AND ELIMINATION. MAIN PHARMACOKINETIC PARAMETERS. PHARMACODYNAMICS: MECHANISMS OF DRUG ACTION; DRUG RECEPTORS; DRUG-RECEPTOR INTERACTIONS; SIGNAL TRANSDUCTION MECHANISMS; AGONISTS AND ANTAGONISTS. NEUROTRANSMITTERS.
SYSTEMATIC PHARMACOLOGY- MECHANISM OF ACTION, THERAPEUTIC EFFECTS AND SIDE EFFECTS OF THE MAIN CLASSES OF DRUGS: AUTONOMIC DRUGS; DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM; CARDIOVASCULAR DRUGS; ANTI-INFLAMMATORY DRUGS; BRONCHODILATORS AND OTHER DRUGS USED IN ASTHMA; DRUGS USED IN GASTROINTESTINAL DISORDERS; CANCER CHEMOTHERAPY; ANTIMICROBIC DRUGS.
PRINCIPLES OF TOXICOLOGY