Università Roma Tre

INTRODUCTION: NATURE OF DRUGS, DRUG NOMENCLATURE, DRUG CLASSIFICATION. CLINICAL AND PRECLINICAL PHARMACOLOGY.
PRINCIPLES OF GENERAL PHARMACOLOGY- PHARMACOKINETICS: THE DYNAMICS OF DRUG ABSORPTION, DISTRIBUTION, BIOTRANSFORMATION AND ELIMINATION. MAIN PHARMACOKINETIC PARAMETERS. PHARMACODYNAMICS: MECHANISMS OF DRUG ACTION; DRUG RECEPTORS; DRUG-RECEPTOR INTERACTIONS; SIGNAL TRANSDUCTION MECHANISMS; AGONISTS AND ANTAGONISTS. NEUROTRANSMITTERS.
SYSTEMATIC PHARMACOLOGY- MECHANISM OF ACTION, THERAPEUTIC EFFECTS AND SIDE EFFECTS OF THE MAIN CLASSES OF DRUGS: AUTONOMIC DRUGS; DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM; CARDIOVASCULAR DRUGS; ANTI-INFLAMMATORY DRUGS; BRONCHODILATORS AND OTHER DRUGS USED IN ASTHMA; DRUGS USED IN GASTROINTESTINAL DISORDERS; CANCER CHEMOTHERAPY; ANTIMICROBIC DRUGS.
PRINCIPLES OF TOXICOLOGY

S.G. CELLA, DI GIULIO AM., GORIO A., SCAGLIONE F. FARMACOLOGIA GENERALE E SPECIALE PER LE LAUREE SANITARIE, PICCIN, 2010;
F. ROSSI, V. CUOMO, C. RICCARDI “FARMACOLOGIA. PRINCIPI DI BASE ED APPLICAZIONI TERAPEUTICHE”, ED. MINERVA MEDICA, TORINO, 2005;
KATZUNG B.C.: "FARMACOLOGIA GENERALE E CLINICA" ED. PICCIN, PADOVA, 2003.
MATERIALE DIDATTICO FORNITO DAL DOCENTE.

KATZUNG B.C.: "BASIC AND CLINICAL PHARMACOLOGY”, 9TH EDITION
RANG H.P., DALE M.M., RITTER J.M., FLOWER R.: “PHARMACOLOGY”, 6TH EDITION